The 5-Year Incidence of Bleb-Related Infection and Its Risk Factors after Filtering Surgeries with Adjunctive Mitomycin C: Collaborative Bleb-Related Infection Incidence and Treatment Study 2 – Corrected Proof

Purpose: To report the 5-year incidence of bleb-related infection after mitomycin C–augmented glaucoma filtering surgery and to investigate the risk factors for infections.Design: Prospective, observational cohort study.Participants: A total of 1098 eyes of 1098 glaucoma patients who had undergone mitomycin C–augmented trabeculectomy or trabeculectomy combined with phacoemulsification and intraocular lens implantation performed at 34 clinical centers.Methods: Patients were followed up at 6-month intervals for 5 years, with special attention given to bleb-related infections. The follow-up data were analyzed via Kaplan-Meier survival analysis and the Cox proportional hazards model.Main Outcome Measures: Incidence of bleb-related infection over 5 years and risk factors (Read more...)

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