Uncategorized
Advances in epi-on techniques may establish new gold standard in corneal cross-linking
In the lively debate over the protocols for corneal collagen cross-linking, epithelium-on techniques have a special place. A transepithelial treatment has advantages in terms of noninvasiveness and safety, but the barrier effect of the epithelium, attenuating riboflavin penetration, UV light absorption and oxygen diffusion, seemed difficult to overcome. Recent developments, however, have brought the epithelium-on option back to the forefront. If the promising results that have been recently documented are confirmed in the long term by larger-scale clinical trials, the transepithelial approach