In a paper in Expert Review of Molecular Diagnostics, Maria Francesca Cordeiro, MD, and colleagues demonstrated that algorithm-aided detection of apoptosing retinal cells can identify early endothelial neovascular activity.
This method predicted onset of wet age-related macular degeneration several months in advance with a specificity of 79% to 90% and sensitivity greater than 80%.
In a previous study, the same method showed efficacy in predicting glaucomatous progressive disease. This way of testing the eye could be the answer to the unmet need of diagnosing AMD early, before significant
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