Author: Healio ophthalmology

Bilateral, contralateral multifocal IOLs yield similar intermediate, distance visual acuity

Bilateral implantation of a multifocal IOL was non-inferior to contralateral implantation of different multifocal IOLs in terms of intermediate and distance visual acuity, according to a study. However, bilateral implantation did not yield comparable near vision.“These results suggest that contralateral implantation might have a higher likelihood than bilateral implantation of patients attaining spectacle independence over a wide range of distances,” the study authors said.

Advances in regenerative medicine may alter treatment of corneal endothelial diseases

The last decade has seen significant advances in the field of corneal surgery. Various lamellar keratoplasty techniques have been refined, and endothelial keratoplasty in the form of Descemet’s stripping automated endothelial keratoplasty has now become the standard for endothelial diseases. Worldwide, DSAEK is now one of the most common techniques for endothelial transplant, with excellent functional outcomes.However, Descemet’s membrane endothelial keratoplasty, with its better functional results and faster visual recovery, is now challenging DSAEK. The concern with DMEK is the handling of the delicate Descemet’s membrane and endothelium and the (Read more...)

Alcon, PowerVision enter strategic alliance to develop accommodating IOL

Alcon has entered into a strategic alliance with PowerVision, according to an Alcon press release.PowerVision has developed an accommodating IOL that has shown the ability in pilot studies to change focus through fluid-driven shape-changing technology. The IOL is for cataract patients with presbyopia, and it is implanted in the capsular bag and utilizes the eye’s natural accommodating muscles to transport fluid in the IOL.

Physician behaviors hinder patients in navigating out-of-pocket costs

Recent qualitative findings published in Health Affairs showed that physicians struggled to help patients factor out-of-pocket expenses into their medical decisions.“Health care consumers cannot expect to make savvy financial decisions if their doctors do not engage with them in productive conversations about the pros and cons of their health care alternatives, including the financial costs,” Peter A. Ubel, MD, professor in the Sanford School of Public Policy at Duke University, told Healio Internal Medicine. “Some physicians say they are reluctant to do so because money talk would contaminate the doctor-patient (Read more...)

Keranova raises €4 million in series A funding for prototype in automated surgery

Keranova reported a series A funding investment of 4 million to finance development of prototype ophthalmic surgical equipment, according to a press release.The technological innovation “allows for a substantial reduction in manual intervention in favor of automation and precision,” which reduces operator-dependent risk, according to the release.

Physicians lack clarity on FDA approvals, ‘breakthrough therapy’

Physicians demonstrated limited understanding of the FDA approval process and the meaning of the “breakthrough therapy” designation, according to recent research in JAMA.“Although the term ‘breakthrough’ leads consumers to overly optimistic beliefs about drug effectiveness, it is not known how physicians understand this term — or more generally, what FDA approval means,” Aaron S. Kesselheim, MD, JD, MPH, of the division of pharmacoepidemiology and pharmacoeconomics at Brigham and Women’s Hospital, and colleagues wrote. “A national survey of board-certified internists and specialists revealed substantial deficits in knowledge of the meaning of (Read more...)

Twice-daily dose of trabodenoson may lower IOP in glaucoma patients

Twice-daily 50 µg to 500 µg ocular doses of trabodenoson were well-tolerated, according to a study, and at 500 µg, a dose-related decrease in IOP was seen in patients with primary open-angle glaucoma or ocular hypertension.The multicenter, randomized, double-masked, placebo-controlled, dose-escalation phase 2 study included 141 patients who were administered 50 µg, 100 µg or 200 µg unilateral topical twice-daily trabodenoson (Inotek Pharmaceuticals) or placebo for 14 days, or 500 µg trabodenoson or placebo for 28 days.

VIDEO: New generation of ophthalmologists embrace technological advancements in glaucoma

BASSANO DEL GRAPPA, Italy — At the Bassano Ophthalmology Meeting, OSN Europe Editorial Board Member Stefano Gandolfi, MD, relates one of the commendable “pros” of the meeting: a cross-generational discussion on technological advancements in the management of complications in glaucoma surgery, which included skills and insights of senior ophthalmologists and of new-generation surgeons.

Bowman’s layer transplantation may be safer surgery for patients with advanced keratoconus

For most eyes with advanced keratoconus, penetrating keratoplasty is a bad option. It permanently weakens the cornea, precipitates cataracts, promotes glaucoma, provides an often uneven and unstable refractive surface, presents the constant risk of allograft reaction and graft rejection, and — perhaps worst of all — produces many unhappy patients, particularly if the surgery was elective and not emergently required.Nevertheless, PK so far remains the most common surgical treatment worldwide for patients with advanced keratoconus. And while alternatives to conventional PK have emerged, including deep anterior lamellar keratoplasty and new (Read more...)