Announcement on Proposed Conversion of Japanese Subsidiary into the Holding Company of Acucela Inc. through Triangular Merger, Application for Listing of Shares as a Domestic Company, and Partial Amendment to the Bylaws of Acucela Inc.

SEATTLE–(BUSINESS WIRE)–Acucela Inc. (located in Seattle, Washington, U.S.A.; the “Company”) (TOKYO:4589), a clinical stage ophthalmology company that specializes in identifying and developing novel therapeutics to treat and slow the progression of sight-threatening ophthalmic diseases, has unanimously resolved at its board of directors meeting held on March 28, 2016 (Pacific Daylight Time) to (i) convert Acucela Japan Kabushiki Kaisha (the “Japan Holding Company”), which was established as a


Minimal regression seen after intrastromal astigmatic keratotomy

Femtosecond laser-assisted cataract surgery with and without non-penetrating femtosecond laser intrastromal astigmatic keratotomy both yielded “small but statistically significant” regressions in surgically induced astigmatism over time, according to a study.The prospective study included 263 eyes that underwent femtosecond laser-assisted cataract surgery; 87 eyes underwent concurrent intrastromal astigmatic keratotomy (ISAK) and a comparator group of 176 eyes did not.