VIVID, VISTA: BCVA better with aflibercept than laser for treatment of DME

ORLANDO, Fla. — Intravitreal aflibercept for diabetic macular edema continues to perform better than laser with regard to best corrected visual acuity, according to a presenter giving 2-year subgroup analysis data of the VIVID and VISTA DME studies here at the Association for Research in Vision and Ophthalmology meeting. Four hundred six patients in the VIVID study and 466 patients in the VISTA study were divided into three arms: those who underwent laser photocoagulation plus sham injection, those who received five monthly intravitreal injections of 2 mg Eylea(aflibercept, Regeneron) followed (Read more...)

Central corneal thickness in glaucoma patients lower with use of prostaglandins

ORLANDO, Fla. — Central corneal thickness was reduced in glaucomatous eyes treated with prostaglandins alone or with combined beta blockers, prostaglandins and carbonic anhydrase inhibitors, according to a poster presented here at the Association for Research in Vision and Ophthalmology meeting. A total of 405 eyes with ocular hypertension, suspected glaucoma, perimetric glaucoma or no glaucoma were followed with standard automated perimetry, 24-hour IOP profile, optic disc photography and optical coherence pachymetry (Heidelberg Engineering) in a trial evaluating diagnostic and prognostic validity of morphometric, sensory and hemodynamic diagnostic procedures in (Read more...)

Fluorescence shows promise for detecting amyloid β in retinas of Alzheimer’s patients

ORLANDO, Fla. — Thioflavin S staining in the ex vivo retina, detected by polarimetry, showed an 84.2% sensitivity and 72.2% specificity in detecting Alzheimer’s disease, according to a poster presented here at the Association for Research in Vision and Ophthalmology meeting. Laura Emptage, a research assistant in the Campbell Labs at the University of Waterloo, and colleagues explained in their poster that because amyloid β is overexpressed in the brains of those with Alzheimer’s disease — and typically detected post-mortem — it is an accepted marker of the disease.