A Method to Estimate the Amount of Neuroretinal Rim Tissue in Glaucoma: Comparison with Current Methods for Measuring Rim Area – Accepted Manuscript

Abstract: Purpose: To test whether the minimum rim area assessed by spectral domain optical coherence tomography (SD-OCT), based on the shortest distance from Bruch’s Membrane Opening (BMO) to the inner limiting membrane, corresponds more closely to retinal nerve fiber layer (RNFL) thickness and visual field mean deviation (MD) than current rim measures in early glaucoma.Design: Prospective cross-sectional study.Methods: 221 participants with non-endstage glaucoma or high-risk ocular hypertension performed standard automated perimetry, and received SD-OCT and confocal scanning laser ophthalmoscopy (CSLO) scans, on the same day. Rim area measured by CSLO was compared with three SD-OCT rim measures from radial B-scans: (Read more...)