On October 12, California Governor Jerry Brown vetoed California Senate Bill 598, which had passed the State Assembly and State Senate with strong bipartisan support. If enacted, Senate Bill 598 would have allowed biosimilars approved by the FDA as in…
What therapies other than corticosteroids are being used in the treatment of inflammatory eye disease, and which ones are currently in translation from the lab to clinical use? BMC Ophthalmology
How effective is combined cataract surgery with implantation of the GTS-400-iStent, and does it help to keep intraocular pressure in check? The British Journal of Ophthalmology
Purpose: To evaluate the efficacy of intravitreal bevacizumab for prevention of macular edema after plaque radiotherapy of uveal melanoma.Design: Retrospective, single-center, nonrandomized, interventional comparative study.Participants: Patients with uveal melanoma treated with plaque radiotherapy were divided into 2 groups: a bevacizumab group and a control group.Intervention: The bevacizumab group received intravitreal bevacizumab injection at the time of plaque removal and every 4 months thereafter for 2 years (total, 7 injections). The control group had no intravitreal bevacizumab injection. Both groups had periodic follow-up with ophthalmoscopy and optical coherence tomography (OCT).Main Outcome Measures: Development of OCT-evident macular edema.Results: There were 292 patients (Read more...)
Purpose: To report postoperative complications in eyes that underwent 25-gauge high-speed pars plana vitrectomy (25G HS-PPV) alone or combined with phaco-vitrectomy surgery for epiretinal membrane, vitreomacular traction, or macular hole.Design: Retros…
Purpose: Fetal mice require light exposure in utero during early gestation for normal vascular development in the eye. Because angiogenic abnormalities in retinopathy of prematurity (ROP) are manifested in preterm infants, we investigated whether day l…