Uncategorized

Interval of injury, vitrectomy a risk factor for proliferative vitreoretinopathy

by  • 

Ocular trauma is associated with a high risk of proliferative vitreoretinopathy and poor postoperative visual outcomes, according to a study. The study included 179 eyes with trauma and proliferative vitreoretinopathy (PVR). A control group comprised 221 eyes with trauma and no PVR. Average follow-up was 11 months in the PVR group and 11.3 months in the control group, except for patients who had primary enucleation or evisceration. The average interval between injury and vitrectomy was 62.6 days in the PVR group and 16.8 days in the control group.

Read more →

Peer-reviewed

Imaging of the Macula Indicates Early Completion of Structural Deficit in Autosomal-Dominant Optic Atrophy – Corrected Proof

by  • 

Purpose: Optical coherence tomography (OCT) enables 3-dimensional imaging of the retina, including the layer of ganglion cells that supplies the optic nerve with its axons. We tested OCT as means of diagnosing and phenotyping autosomal-dominant optic atrophy (ADOA).Design: Cross-sectional study.Participants: The study included 49 patients with OPA1 exon 28 (2826delT) ADOA (age, 8.6–71.5 years; best-corrected visual acuity [BCVA], 20/700–20/20) and 51 mutation-free first-degree relatives as healthy controls (BCVA 20/25–20/10).Methods: Participants underwent routine examination, including automated perimetry, and OCT with segmentation of the perifoveal retinal ganglion cell–inner plexiform layer (GC-IPL) and the peripapillary retinal nerve fiber layer (RNFL).Main Outcome Measures: Perifoveal (Read more...)