Purpose: To assess baseline and follow-up characteristics of choroidal neovascularization (CNV) lesions in age-related macular degeneration in relation to the development of subfoveal subretinal fibrosis.Design: Retrospective, observational case series…
Mutations Identified in High-Grade Myopia
Mutations implicate altered copper metabolism in high-grade myopia. Medscape Medical News
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GEFAL results support CATT, IVAN findings
SEATTLE — Like the CATT and IVAN trials, the French Evaluation Group Avastin Versus Lucentis found also that bevacizumab is non-inferior to ranibizumab, the GEFAL investigators reported here.“We found that, for our primary outcome, which is visual acuity, bevacizumab is non-inferior to ranibizumab,” study author Laurent Kodjikian, MD, PhD, said in a press briefing at the Association for Research in Vision and Ophthalmology meeting. The mean visual acuity difference between the two drugs was 1.89 letters, which is clinically meaningless, Kodjikian said.
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Novel VEGFR/PDGFR inhibitor well-tolerated in treatment of wet AMD
A new treatment for neovascular age-related macular degeneration was well-tolerated and showed potential efficacy, according to a news release.At the Association for Research in Vision and Ophthalmology meeting, Xcovery Vision released preliminary data…
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Nonpenetrating brachytherapy device shows positive early safety, efficacy results
SEATTLE — A new brachytherapy approach has been shown to increase best corrected visual acuity and was well-tolerated in a small group of patients with age-related macular degeneration, according to a poster presentation here. Kamaljit S. Balaggan, MBBS, and colleagues presented a poster at the Association for Research in Vision and Ophthalmology meeting on the early results with the SMD-1 novel episcleral brachytherapy device developed by SalutarisMD. The class 1 medical device delivers 24 Gy of radiation for 5.5 minutes to the macula through a probe placed adjacent to the (Read more...)
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ARMOR study shows multi-drug resistance continues to be a challenge
SEATTLE — Four-year results of the ARMOR study showed that a number of isolates are resistant to common ophthalmic antibiotics, and methicillin-resistant Staphylococcus aureus and methicillin-resistant coagulase-negative staphylococci isolate resistance to multiple ophthalmic drugs remains high, according to a poster here. The Antibiotic Resistance Monitoring in Ocular Microorganisms (ARMOR) study to date has looked at 455 isolates from 25 clinical sites, according to a poster by Wolfgang Haas, PhD, and colleagues at the Association for Research in Vision and Ophthalmology meeting.