Dr Jeffrey Weber assesses the benefit of immunotherapies in two rare subtypes of melanoma and finds that rates of survival and duration of response trail well behind those associated with cutaneous melanoma. Medscape Oncology
Tag: Hematology-Oncology
Therapeutic Options for Retinoblastoma
Over the past decade, localized chemotherapy and targeted drugs have become therapeutic options for retinoblastoma. Cancer Control: Journal of the Moffitt Cancer Center
Researchers Make Progress in Unraveling Uveal Melanoma
Two studies from the University of Miami Miller School of Medicine shed light on physiological and genetic factors associated with uveal melanoma (UM). Reuters Health Information
New Strategies but Modest Benefit in Uveal Melanoma
New therapies being tried in uveual melanoma include combination everolimus, pasireotide long-acting release, and the MEK inhibitor trametinib. Medscape Medical News
Experts Weigh In on 21st Century Cures Act
Experts highlight the pros and cons of the 21st Century Cures Act. Medscape Oncology
Emperor’s Mukherjee on the Three Laws of Medicine
Eric Topol speaks with author Siddhartha Mukherjee about his latest book, The Laws of Medicine, and how uncertainty, imperfections, priors, outliers, and biases affect these laws. Medscape
Chemosurgery Appears No Less Safe Than Enucleation in Advanced Eye Cancer
Ophthalmic artery chemosurgery (OAC) for advanced-stage retinoblastoma appears at least as safe as enucleation, according to New York-based researchers. Reuters Health Information
Mukherjee and Hudis on ‘Emperor’s’ Journey to PBS
Oncologists Cliff Hudis, past president of ASCO, and Sid Mukherjee talk about the PBS documentary adapted from Mukherjee’s Pulitzer Prize-winning book, The Emperor of All Maladies. Medscape Oncology
Ipilimumab in Uveal Melanoma: Long-Lasting Responses in 25%
The first trial of ipilimumab in patients with uveal melanoma has shown some long-lasting responses in a patient population with poor prognosis. Medscape Medical News
3D Printer Makes Mask in Hours for Eye Cancer Patients
Miami researchers can make flexible, customized prostheses at a fraction of the usual cost for patients whose eye cancer has left a hollow socket. Medscape Medical News
Targeted Retinoblastoma Management
This new study explores the outcomes of several methods of chemotherapy delivery for the targeted treatment of retinoblastoma. Current Opinion in Ophthalmology
Selumetinib Yields Modest Benefits in Rare Eye Cancer
The first randomized controlled trial of the MEK inhibitor selumetinib finds modest improvement in clinical outcomes of advanced uveal melanoma but high rates of adverse effects. Medscape Medical News
Legalize Medical Marijuana, Doctors Say in Survey
A majority of doctors say that medical marijuana should be legalized nationally and that it can deliver real benefits to patients, a new survey by WebMD/Medscape finds WebMD Health News
For Ocular Melanoma Mets to Liver, Fotemustine Disappoints
For patients with uveal melanoma (UM) metastases in the liver, response rates and progression-free survival are only slightly better if fotemustine is given through the hepatic artery rather then intravenously, new data show. Reuters Health Information
Taking the Boards: A Frisking, Then a Mugging
Dr. John Marshall found board certification ‘really hard,’ partly because questions had no right answer. He asks: Are boards a fair measure of a practicing physician’s skills and knowledge base? Medscape Oncology
Bevacizumab May Bring Back Vision in Optic Pathway Gliomas
Bevacizumab treatment of children with optic pathway gliomas (OPG) appears to produce marked recovery of vision, according to a new report of four cases. Reuters Health Information
Lampalizumab Appears Safe for Dry Macular Degeneration
No significant safety signals emerged after the first-ever use of anti-factor D for dry age-related macular degeneration, results of the MAHALO trial show. Medscape Medical News
Palladium-103 Radiation Effective for Small Choroidal Melanoma
Palladium-103 plaque radiation therapy was effective for treating small choroidal melanomas in a retrospective study. Reuters Health Information
Genomic Medicine Just Hit the Accelerator
Eric Topol, MD, talks about the Supreme Court ruling disallowing patenting of genes, as well as new initiatives for advancing the sharing of genetic data. Medscape Internal Medicine
Breakthrough in Rare Eye Cancer: First Drug That Works
For the first time, a systemic therapy has shown clinical activity in a rare eye cancer, metastatic uveal melanoma, for which there is no standard treatment. Medscape Medical News