Corneal collagen cross-linking (CXL) helps control keratoconus progression in all age groups, but it works best in adults under 40, new data suggest. The procedure involves a photo-oxidative reaction, catalyzed by riboflavin, that stiffens the cornea. …
Category: Cornea
Bandage contact lenses under development as drug delivery vehicles
WAIKOLOA, Hawaii — Bandage contact lenses, which provide pain relief and comfort from exposed nerve endings that occur with corneal maladies such as corneal abrasions from corneal dystrophies, neurotrophic keratopathy, bullous keratopathy and postsurgical states, may also be developed into drug delivery vehicles, a speaker said here. “The motivating factor for this development is that the eye, the cornea in particular, has a very strong bioprotective mechanism. It allows low permeability of medicine to get into the eye. We know that the tear fluid that drains into the nasal cavity (Read more...)
DMEK minimizes drawbacks of PK
WAIKOLOA, Hawaii — Endothelial keratoplasty procedures only replace the part of the cornea that is dysfunctional, making them potentially safer and yielding better visual results compared with penetrating keratoplasty, a speaker said here.“As we get more experience, we are becoming more exact in the way that we do the tissue replacement,” Francis W. Price Jr., MD, said at Hawaiian Eye 2013.
Novel Technique Using Stem Cells Revives Damaged Eye
Treating blindness caused by burns using limbal stem cells harvested from the undamaged eye of the same patient has now become cheaper, easier and safer. Results of a pilot study of the SLET (simplified technique of limbal transplantation) technique co…
Denali Concrete Management Inc. Announces The Commencement Of Patient Enrollment For The Phase 3 Dry Eye Syndrome Study
Denali Concrete Management Inc. (OTCBB: DCMG) announced that it has commenced patient enrollment for a phase 3 clinical study of the safety and efficacy of CF101, daily administered orally, in patients with moderate-to-severe Dry Eye Syndrome. This mul…
Status of Strategic Partnership Discussions Related to RGN-259 Ophthalmic Eye Drop
ROCKVILLE, Md.–(BUSINESS WIRE)–RegeneRx Biopharmaceuticals, Inc. (OTC Bulletin Board: RGRX) (“the Company” or “RegeneRx”) is updating stockholders on the status of strategic discussions related to its ophthalmic drug candidate, RGN-259. Since…
Breakthrough In Treatment To Prevent Blindness
A UCSF study shows a popular treatment for a potentially blinding eye infection is just as effective if given every six months versus annually. This randomized study on trachoma, the leading cause of infection-caused blindness in the world, could poten…
New Dry Eye Treatments in the Pipeline
OSN: Several promising treatments are in the pipeline for dry eye, which is an “epidemic” and can drive patients to drink. Secretagogues stimulate the eye to produce its own tears, like Restasis. One is called Lancovutide which was originally used in cystic fibrosis. Rebamipide’s mechanism is to increase the mucin level in tears, which makes […]
Avedro Update: Company Completes U.S. Phase III Study of Microwave Treatment for Progressive Keratoconus and Ectasia after Refractive Surgery
I have been following the progress of Avedro since I first learned about the formation of the company back in May 2009. Now the company has announced completion of the one-year follow up visits of patients enrolled in its two…
Corneal Tissue Can Be Shared for Transplant
Ophthalmology: Today, surgeons often use just part of the cornea for transplant- either the anterior (front) part or posterior part. Transplanting the entire cornea is becoming less common. This study demonstrated something that would seem logical- instead of throwing out the rest of the unused cornea, it can be used for a transplant in another […]
New Method Attacks Bacterial Infections on Contact Lenses
Researchers at National Jewish Health and the University of Texas Southwestern Medical Center have discovered a new method to fight bacterial infections associated with contact lenses. The method may also have applications for bacterial infections as…
Mimetogen Pharmaceuticals Announces Initiation Of Phase II Clinical Trial Of Novel NGF Mimetic In Patients With Dry Eye
Mimetogen Pharmaceuticals Inc., a clinical-stage biotechnology company focused on developing novel small molecule compounds that mimic the effects of neurotrophins, today announced that it has initiated the first human clinical trial evaluating MIM-D…
BioSynthetic Corneas A Reality?
Mechanisms of Corneal Allergic Reaction: New Options for Treatment
What are the most current and effective treatments for corneal allergic reactions? Expert Review of Ophthalmology
Corneal Cross-Linking in Children With Keratoconus Improves Visual Acuity
Corneal collagen cross-linking appears to be safe and effective for children with progressive keratoconus. Medscape Medical News
Pediatric Corneal Graft Failure Related to Procedure Type
In children, about 1 in 7 penetrating corneal grafts fail, mainly because of irreversible rejection, but the underlying condition is also influential, Australian researchers report in an October 7th online paper in Ophthalmology. Reuters Health Infor…
Corneal cross-linking for treatment of keratoconus
New abstract in the Health Technology Assessment (HTA) Database from the Centre for Reviews and Dissemination
Contact Lenses: A Safe Option When Used Properly
For 40 million Americans, using contact lenses to improve vision is a way of life. While a good number adhere to the medical guidelines for wearing contacts, according to the American Optometric Association’s (AOA) annual American Eye-Q® survey, many …