Tag: Nanomedicine

Neurons Grow on Crosslinks of Carbon Nanotubes

Carbon nanotubes have a host of interesting properties. They are biocompatible and electrically conductive, so have been investigated as a possible material for growing nerve tissues. To make carbon nanotubes cooperate as desired, novel forms are required and researchers at SISSA (International School for Advanced Studies) and University of Trieste (Read more...)

LipoGlo Makes Bad Cholesterol Glow Inside Zebrafish

So-called “bad cholesterol” is a molecular complex of fat and protein. Specifically, the protein is Apolipoprotein-B, or ApoB, and the fat is cholesterol. While ApoB helps fat molecules to move around the blood vasculature, it is also what makes cholesterol stick to vessel walls, forming dangerous plaques that are one of the main causes (Read more...)

Artificial Protein Switch for Smart Cell Therapies

Researchers from University of California, San Francisco and the University of Washington have developed a new artificial protein switch, dubbed LOCKR. Their work demonstrates that the new switch can be used to control many intracellular processes, including mediating molecular traffic inside a cell, degrading specific proteins, and causing a cell (Read more...)

Using Microparticles to Measure Oxygen in Tissues

The field of tissue engineering is rapidly progressing, in large part thanks to hydrogel scaffolds that provide a comfortable home for new cells. A major issue that researchers bump against is tracking how well oxygen reaches freshly grown cells within such scaffolds, which can indicate how well the new cells are generally functioning. Now, researc (Read more...)

Self-Powered Microrobots Deliver Drugs to Tumors in the Gut

Treating tumors within the GI system is often a difficult challenge, frequently requiring invasive surgery. Scientists at Caltech have now developed self-propelled microrobots that can deliver drugs to precise spots within the intestines, and that can let clinicians monitor and control their activity. Besides drug delivery, the microrobots have the (Read more...)

Thin Microgels Encapsulate and Protect Therapeutic Cells

Cell-based therapies, such as those involving the delivery of stem cells, require a way to encapsulate cells inside a protective package in order for them to not be destroyed and washed out by the body. There have been successful attempts to contain therapeutic cells within hydrogels, but the resulting materials were bulky and could not […]

New Nanoparticles Help Spinal Cords to Heal Following Injury

When people damage their spinal cords, a lot of the long-term consequences often stem from the body’s overreaction to the injury. That’s because the blood-brain barrier protecting the spinal cord becomes compromised and overly aggressive immune cells flood in. Now, a team from the University of Michigan has developed a way of using intr (Read more...)

Tiny Nanowire Probes Measure Intracellular Electrical Activity

Researchers at the University of Surrey and Harvard University have developed tiny nanoprobes that can measure electrical signals inside cells, such as neurons and cardiac cells. Unlike previous technology for intracellular electrophysiology, the nanoprobes cause minimal destruction to the cells, and could pave the way for human-machine interfaces (Read more...)

Superhydrophic “Nanoflowers” for Biomedical Applications

Researchers from Texas A&M University have developed new nanomaterial with superhydrophobic properties. Their recent publication demonstrates that by controlling atomic-scale defects in their nanomaterial, they could use it to repel water and blood on glass, paper, and other common materials. This exciting development can lead to self-cleaning (Read more...)

Crystallized Drugs to Protect Implants from Immune Attack

Implantable medical devices that intimately interact with the human body are often subject to the immune system’s foreign body response (FBR). This creates scarring around the implants, reducing their functionality over time. Now, scientists at MIT have developed a way to embed crystallized immunosuppressant drugs into implantable devices so (Read more...)

Nano-emulsions for Drug Delivery Through Skin

Researchers from MIT have developed a new chemical nanoemulsion that can help deliver drugs through the skin. Their work demonstrates that, only by using a handful of FDA-approved materials, they can create nano-sized emulsions which turn to gels when they come in contact with the body. These nano-emulsions may have interesting properties for drug (Read more...)

Magnetic Nanoclusters For Tumor Destruction

A wide variety of magnetic nanoparticles have been developed by researchers. These devices can be injected into tumors and, using a magnetic field, made to heat up and kill cancer cells. One major challenge with using such nanoparticles is that they are usually expected to be injected using a syringe directly into a tumor, but […]

Tiny Implant Driven by Bluetooth Delivers Drugs Inside Body

Many drugs come with complicated dosing regimens, making it difficult for patients to keep track of when it is time to take the next pill. Those taking drugs for hypertension, rheumatism, and other conditions can have very personalized schedules that require accurate timing. Researchers at Houston Methodist hospital have now developed an implantabl (Read more...)

Microrobot Developed for Delivery of Stem Cells to the Brain

Researchers from Daegu Gyeongbuk Institute of Science and Technology (DGIST) in South Korea have developed a new microrobot that can precisely deliver therapeutic cells to very specific parts of the brain. Their work, recently published in Science Robotics, demonstrates that neural stem cells can be cultured and differentiated on their robot and th (Read more...)

Contrast Agent Uses Heart’s Electricity to Activate Itself

Imaging the heart for signs of disease is still quite rudimentary. While CT, ultrasound, and PET (positron-emission tomography) scanners generate impressive looking graphics, they’re a long way from giving doctors a true representation of the anatomy and function of the heart and nearby vasculature. Contrast agents are widely used to allow th (Read more...)

Molecular Motors Drill Through Cancer Cells

A couple of years ago a team of U.S. and U.K. scientists came up with a way of making molecular motors that can drill through cancer cells, destroying them in the process. The researchers, from Rice University, Durham University, and North Carolina State University, used an ultraviolet (UV) light source to energize these motors, but […]