Tag: Nanomedicine

3D Liquid-Cell Electron Microscopy Imaging Now Possible

Electron microscopy revealed a world that exists at scales smaller than the wavelength of light. Advancements in this field have allowed scientists to visualize ever more objects and processes, but actually seeing living cells in 3D and within a liquid environment has been impossible. Now, a team of researchers from Penn State University, Virginia (Read more...)

Peptide Particles Ferry Drugs Across Blood-Brain Barrier

Most drugs, genetic materials, and other therapeutic agents are very difficult to use inside the brain because of the blood-brain barrier. There have been attempts to use ultrasound and microbubbles to create temporary passages through the barrier, including as a possible therapy for Alzheimer’s disease, but this is approach is not easy or id (Read more...)

Light Activated Compound Kills Hypoxic Tumors

Photodynamic therapy is a technique that relies on photosensitizer chemicals to generate reactive species that kill cancer cells. These compounds can be delivered into tumors and then light is used to activate them. One of the main reasons for the slow adoption of this technology is that tumors are usually oxygen deprived and the photosensitizers [ (Read more...)

Minimally Invasive Biopsies Provide Maximum Pathology Data

Current pathology techniques for analyzing biopsy tissues are lacking in their ability to detect cancer in small samples. Being able to rapidly study the distribution of protein expression within cells, gathered from minuscule samples, could be an important tool for early diagnosis and monitoring of cancer. Now, researchers at National University o (Read more...)

Bacterial Swarmbots to Produce Biologic Drugs

Biologics, being a group of drugs synthesized from biological sources, are often produced using bacteria. The manufacturing processes are usually slow and laborious, though they do benefit from economies of scale. Producing small quantities of biologics is typically limited to research labs, and even there it is limited in scope. Researchers at Duk (Read more...)

Magnetically Controlled Microbots for Drug Delivery and Hyperthermia Therapy in Cancer

Researchers in Daegu Gyeongbuk Institute of Science and Technology in South Korea have developed biodegradable microrobots that can be magnetically controlled to deliver drugs and provide hyperthermia treatment at the site of a tumor. This latest research effort attempts to provide a delivery option for two different therapy pypes by creating biode (Read more...)

Nanoscale Light Manipulation for Detection of Tiny Pathogens

Viruses are so small that to be able to detect them using light you need instruments that work on the nanoscale. Sensors so perfect are very hard to make, as most manufacturing processes disrupt nanoscale structures. Now, a team at Purdue University has developed a way to combine 3D plasmonic nanoarrays, special light manipulation devices, [&hellip (Read more...)

Plugging Holes in Blood Vessels Caused by Nanoparticle Therapy

While targeting nanoparticles to attack cancer cells can be effective at reducing primary tumors, they tend to create tiny holes within blood vessel walls that let some cancer cells escape and metastasize elsewhere. This is a serious side effect that may limit the usefulness of many nanoparticle-based cancer therapies in the long run, so researcher (Read more...)

Gold Nanostars Help Design New Nanomedicines

Researchers from Northwestern University have developed a novel way to track how nanoparticles interact with cancer cells and whether they reach their tagets. The team’s work shows that if a nanoparticle targets cancer cells, it undergoes more rotational and translational movement compared to nanoparticles that cannot target cancer cells effe (Read more...)

Neurons Grow on Crosslinks of Carbon Nanotubes

Carbon nanotubes have a host of interesting properties. They are biocompatible and electrically conductive, so have been investigated as a possible material for growing nerve tissues. To make carbon nanotubes cooperate as desired, novel forms are required and researchers at SISSA (International School for Advanced Studies) and University of Trieste (Read more...)

LipoGlo Makes Bad Cholesterol Glow Inside Zebrafish

So-called “bad cholesterol” is a molecular complex of fat and protein. Specifically, the protein is Apolipoprotein-B, or ApoB, and the fat is cholesterol. While ApoB helps fat molecules to move around the blood vasculature, it is also what makes cholesterol stick to vessel walls, forming dangerous plaques that are one of the main causes (Read more...)