Tag: Oncology

Spinning Disc Separates Circulating Tumor Cells from Blood

A team of researchers at Daegu Gyeongbuk Institute of Science & Technology in Korea created a centrifugal system to separate circulating tumor cells from blood samples. Resembling a DVD, the device separates the cells using the centrifugal force created when it is spun. A layer of white blood cells and circulating tumor cells is formed [&hellip (Read more...)

Automated Wearable Breast Ultrasound System: Interview with Maryam Ziaei, CEO of iSono Health

iSono Health, a medtech company based in San Francisco, has created the ATUSA System, a wearable 3D ultrasound breast scanning system. The device is worn on the breast, and does not rely on operator experience or skill to obtain consistent, high quality breast scans. As the scanning takes place automatically, it can be used by […]

Photonic Technique for Deeper Fluorescent Sensors

Researchers at MIT have developed a method that lets them read the signal from fluorescent sensors that are as deep as 5.5 centimeters in tissue. Previously, it was very difficult to get a good signal from a fluorescent sensor placed that deep, as fluorescence emitted by the tissue itself would muddy the signal. The new […]

Advanced Multi-Organ Chip for Personalized Medicine

Researchers at Columbia University School of Engineering and Applied Science developed an advanced organ-on-a-chip system that incorporates heart, bone, liver, and skin tissue in independent niches that are linked with simulated vascular flows. The system even includes immune cells that circulate within the simulated vasculature. The technology rep (Read more...)

Soft Robotic Sleeve for Lymphedema Treatment

Researchers at the University of Waterloo in Canada created a soft robotic sleeve to treat lymphedema. Lymphedema involves fluid accumulation in tissues because of damage to the lymph system. This wearable sleeve combines a microfluidic controller and soft robotic components that apply compression to the arm to reduce and control fluid accumulation (Read more...)

Wireless Implant for Anti-Cancer Photodynamic Therapy

Researchers at Texas A&M University created a wireless device that aims to illuminate and destroy residual tumor cells left after cancer resection. The device can be used by surgeons to illuminate the tumor bed after resection. It works in combination with a photosensitizer drug that is administered before the procedure and accumulates in tumor (Read more...)

Molecular Robots Swarm to Deliver Cargo

Researchers at Hokkaido University in Japan created molecular robots that can employ swarm behaviors to move and release small cargoes. The robots can be controlled using light, and they consist of biological components, including DNA, microtubules, which are a cytoskeletal component, and kinesin, which is a motor protein that interacts with microt (Read more...)

Optical Therapy Leads to Cancer Apoptosis

Researchers at Okayama University in Japan developed a novel technique to induce cancer cell apoptosis using light. The technology involves modifying the cells to express a light-sensitive protein that rapidly pumps hydrogen ions out of the cell when it is stimulated with light. This increase in cell alkalinity causes it to undergo apoptosis, a for (Read more...)

Acoustic Tweezers Help Characterize Cell Interactions

Researchers at Duke University created an acoustic tweezer system that can precisely manipulate cells and particles. The device can be used to study the interactions between cells, for instance by precisely selecting two cells in a sample and bringing them together gently to study the adhesion force between them. This could be useful in discovering (Read more...)

Cell-Loaded Beads Release Cytokines to Eradicate Tumors

Researchers at Rice University have created a cytokine delivery system that can produce localized immunotherapy at a tumor site for 15-30 days. The technology consists of cytokine-producing ARPE-19 cells that the researchers have encapsulated in small polymer beads. The beads can be delivered into the body using minimally invasive techniques and th (Read more...)

MRI-Guided Magnetic Seeds Heat and Destroy Tumors

Scientists at University College London have developed a highly targeted anti-tumor treatment. The approach involves guiding ferromagnetic thermoseeds to the site of a tumor using the magnetic fields generated by an MRI scanner. The magnetic seeds can then destroy the tumor through localized heating that is induced by an MR-compatible thermoablativ (Read more...)

Optical Biopsy to Spot Tumors Among Healthy Tissue

Researchers at Orel State University in Russia have developed a biopsy system that can distinguish between healthy and cancerous tissue in many clinical cases. The device is designed to address the difficulties that clinicians may experience when trying to obtain a biopsy of a liver tumor, where it can be difficult to know if the […]

Hairy Nanocrystals Capture Chemo Drugs

Researchers at Penn State working with collaborators have developed a nanomaterial that can ‘mop up’ chemotherapeutics in the bloodstream, helping to reduce off-target effects. The technology is intended for use in situations where a chemotherapeutic can be delivered precisely to the site of a tumor, and not in situations where it is de (Read more...)

New Hydrogel Material for Vocal Cord Repair

Researchers at McGill University developed a tough hydrogel that can resist mechanical forces found in the body. However, the material still provides a friendly environment for encapsulated cells to grow and enables the deep perfusion of blood and other tissue fluids. The injectable biomaterial may be useful in repairing tissues that experience con (Read more...)

Fish-Shaped Microrobots to Deliver Chemotherapy to Tumors

Researchers from the University of Science and Technology of China, working with outside collaborators, have developed shape-shifting microrobots that are designed to be guided to a target area in the body using magnets, and then release a drug cargo in response to the local environment. The application that the researchers have pursued involves gu (Read more...)

Cold Cap Therapy for Chemo Patients: Interview with Kate Dilligan, CEO of Cooler Heads Care

Cooler Heads Care, a medtech company based in San Diego, created Amma, a cold cap therapy device that aims to help chemotherapy patients to preserve their hair. Hair loss is a very common side-effect of chemo, and poses a significant psychological challenge for patients who are already struggling with their diagnosis and treatment. Simply cooling [ (Read more...)

Weighing Cancer Cells for Chemotherapy Susceptibility Testing

A collaboration between groups at MIT and Dana-Farber Cancer Institute led to the creation of a system that allows for quick determination of the susceptibility of cancer cells to specific drugs, without the need to rely on genomic markers. The technique consists of flowing the cells through vibrating microchannels, which lets the researchers obtai (Read more...)

Handheld Photoacoustic Device for Lymph Node Assessment

Researchers at Pohang University of Science & Technology in South Korea have developed a handheld photoacoustic device that can locate sentinel lymph nodes near the armpit. The technology could help clinicians to locate the correct lymph node from which to take a biopsy when checking for breast cancer metastases. At present, this process involv (Read more...)

Pancreatic Organoids Grown Inside Synthetic Gel

A team at MIT has developed a technique to grow organoids, both from healthy and cancerous pancreatic tissue, using a synthetic gel that predictably mimics the pancreatic extracellular environment. Compared with naturally derived materials, the synthetic gel is consistent from batch to batch, meaning that it leads to more reproducible and predictab (Read more...)