WAIKOLOA, Hawaii — Genetic testing is available to identify mutations in genes known to cause dominant and recessive forms of inherited glaucoma, a speaker said here.According to Janey L. Wiggs, MD, PhD, genetic testing for early-onset forms of glaucoma can provide valuable diagnostic and prognostic information.
Category: Glaucoma
OCT may detect pre-perimetric changes in glaucomatous eyes
WAIKOLOA, Hawaii — Optic nerve head microcirculation is reduced in glaucoma patients, a speaker said here.“Conventionally, OCT is used to measure structure with micron precision, and that has been very useful in terms of characterizing the structure of the optic nerve head, the nerve fiber layer and the ganglion cell complex,” David Huang, MD, PhD, said at Hawaiian Eye 2013. “We developed a technique where we decomposed the OCT image into several spectral bands and analyzed them separately and recombined them to enhance a signal of flow.”
Individualized glaucoma surgery offers effective results
WAIKOLOA, Hawaii — Glaucoma surgery should be individualized to each patient’s specific needs and form of glaucoma, a speaker said here.According to Thomas W. Samuelson, MD, OSN Glaucoma Section Editor, reducing glaucoma surgical complications is now easier for physicians due to the availability of the correct surgical tools.
Goniotomy, trabeculotomy produce most successful results in pediatric glaucoma
WAIKOLOA, Hawaii — Goniotomy and trabeculotomy are the most effective surgical methods for infantile glaucoma, a speaker said here.“The first thing that’s most important in these surgeries is visualization,” Ken K. Nischal, MD, FRCOphth, said at Hawaiian Eye 2013. “It’s really important to understand that the goniolens you use will affect how easy or how difficult the procedure becomes.”
Daily IOP changes undermine measurement, medication
Day-to-day variability significantly undermines the precision of intraocular pressure measurement and the estimation of medication effectiveness in glaucoma patients, report researchers.Licensed from Medwire news with permission from Springer Healthcar…
EyeTechCare Announces Preliminary Clinical Trial Results of EyeMUST
EyeTechCare SA, a company developing non-invasive therapeutic medical devices using ultrasound technology for ophthalmology market, has announced the preliminary results of EyeMUST, a multicenter study of the use of its EyeOP1 device in glaucoma. The…
“Preservative Toxicity a Disease,” Reports Working Group on Glaucoma Medication Preservatives Toxicity
Valeant Ophthalmics, a division of Valeant Pharmaceuticals North America LLC, announced that the Working Group on Preservatives Toxicity in Glaucoma Medications, an advisory panel of glaucoma treatment experts, was recently convened as an ongoing group…
Bevacizumab Prevents Posttrabeculectomy Complications
The antiangiogenesis agent bevacizumab had an 80% success rate in the maintenance of postoperative improvement in intraocular pressure (IOP) after trabeculectomy. In addition, the drug reduced the incidence of subconjunctival scarring, according to fin…
Intake of Calcium, Iron Supplement Associated With Glaucoma
Supplementary consumption of the oxidants calcium and iron may be a risk factor for the development of glaucomatous disease, according to a study in Investigative Ophthalmology and Visual Science. The investigators reviewed the 2007 to 2008 National He…
Outside temperatures, sun exposure and gender may trigger glaucoma
When it comes to whether or not you will develop exfoliation syndrome — an eye condition that is a leading cause of secondary open-angle glaucoma and increased risk of cataract as well as cataract surgery complications — age, gender and where you liv…
Two-At-Once Visual Field Testing: More Efficient, Equally Accurate
Ophthalmology practices could save time and money by performing visual field (VF) testing on more than one patient at a time, say researchers at the University of Michigan. Their study, published online November 23 in Ophthalmology, found no decrease i…
Ivantis Announces Results of Hydrus Implant Study
Last week, Ivantis announced the 6-month results from its multi-center, international Hydrus I study at the European Society of Cataract and Refractive Surgery Meeting (ESCRS). The Hydrus(TM) Intracanalicular Implant, roughly the size of an eyelash, is placed through a minimally invasive, microsurgical procedure and is designed to reduce eye pressure by reestablishing the patient’s conventional […]
Canaloplasty an Option in Open-Angle Glaucoma
Canaloplasty works just as well as trabeculectomy in reducing intraocular pressure (IOP) in patients with open-angle glaucoma, according to a comparative case series in Ophthalmology.
Acucela and Otsuka Pharmaceutical Announce the Initiation of a Phase 1/2 Clinical Trial for OPA-6566 in Patients with Open-angle Glaucoma or Ocular Hypertension
SEATTLE & TOKYO–(BUSINESS WIRE)–Acucela Inc., a clinical-stage biotechnology company focused on developing new treatments for blinding eye diseases, and Otsuka Pharmaceutical Co., Ltd., today announced the initiation of a Phase 1/2 clinical trial for…
Transcend Medical Closes $51M Series B Financing
Transcend Medical, Inc., an ophthalmic device company dedicated to developing minimally invasive glaucoma therapies, announced the closure of its second tranche, bringing the total of Series B to $51M. Investor Growth Capital (IGC) joined this tranche,…
Oxidative Metabolism in the Eye Differs According to Race
Greater oxygen levels among people of African descent may help explain their higher risk for glaucoma. Medscape Medical News
Improving Patients’ Adherence to Glaucoma Therapy
Patients’ adherence to drug therapy to control
chronic diseases is notoriously poor, particularly
when the disease is asymptomatic. Moreover,
self-reporting of adherence correlates very
poorly with reality. How can you improve this situation…
Reconsidering the Gold Standard of Tonometry
IOP is one of the key metrics used to monitor the
health of an eye, especially an eye with glaucoma.
Tonometry is the act of estimating the IOP. It is not a
measurement of eye pressure, only an estimate. An
exact measurement of IOP requires li…
The Role of Surgical Intervention in Reducing Costs
Several years ago, when a senior
official at the FDA was asked why
there was such a difference in getting
licensing for glaucoma medicines
compared to glaucoma devices, the
answer, slightly in jest, was, “The device
has only got to show it…
An Industry Perspective
Anyone reading Glaucoma Today knows that
some 3 million Americans suffer from this neurodegenerative
disease. Thanks to its size, this
market continues to attract extensive investment
in drug development, which has provided physicians
and the…