Tag: Genetics

Nanopropellers to Deliver Gene Therapy Into Cells

Researchers at the Max Planck Institute for Intelligent Systems in Germany have developed powerful nanopropellers that can be steered into the interior of cells to deliver gene therapy. The magnets that these devices, each about the size of a bacteria, are made of were created for the first time for this very task. Most powerful […]

CRISPR-Based Test to Diagnose COVID-19 in Less than One Hour

With the COVID-19 pandemic growing globally, new ways of detecting the infection is the need of the hour. University of California, San Francisco researchers have recently published a paper in Nature Biotechnology outlining their approach to diagnose COVID-19 infections from respiratory swabs using CRISPR. The test, called the SARS-CoV2 DETECTR ass (Read more...)

Artificial Self-Assembled Blood Vessels

A team of researchers headed by groups at University of Nottingham and Queen Mary University London have come up with a smart material that forms into new blood vessels. Made out of graphene oxide and a protein, the material is 3D printed and naturally forms into tubular shapes that are very similar to blood vessels. […]

New Customizable Bio-Ink for Printing Organs, Tissues

3D printing of tissues and organs requires a bio-ink that can host the living cells that are required for every unique application. A viable construct requires an extracellular matrix that will have the right mechanical and biochemical properties for the intended cells. Researchers at Rutgers University believe they’re on track to being able (Read more...)

Genomic Profiling for Precision Medicine: Interview with David Spetzler, Caris Life Sciences

Caris Life Sciences, a Dallas-based innovator in molecular science focused on fulfilling the promise of precision medicine, has developed the MI Genomic Profiling Similarity (GPS) score to compare the molecular characteristics of specific tumors against those in the Caris database. This allows clinicians to identify the molecular subtype of their p (Read more...)

Device Links Up to 10 Organ Chips to Form Body-on-a-Chip

Researchers at the Harvard Wyss Institute have developed a “body-on-a-chip” consisting of up to 10 organ-on-a-chip devices that are linked together to mimic blood flow between different organ systems. The new system allows for more comprehensive drug testing, enabling researchers to see the effects of a drug on multiple organ systems si (Read more...)

Eyevensys Non-Viral Gene Therapy for Ocular Diseases: Interview with Patricia Zilliox, CEO of Eyevensys

Eyevensys, a clinical-stage biotechnology company based in France, has developed a method to perform non-viral gene therapy in the eye, with the aim of treating ocular diseases. The system uses ocular electrotransfection to deliver therapeutic genes into the eye. Consisting of an ocular device and an electrical pulse generator, the system can deliv (Read more...)

Artificial Protein Switch for Smart Cell Therapies

Researchers from University of California, San Francisco and the University of Washington have developed a new artificial protein switch, dubbed LOCKR. Their work demonstrates that the new switch can be used to control many intracellular processes, including mediating molecular traffic inside a cell, degrading specific proteins, and causing a cell (Read more...)

Using Microparticles to Measure Oxygen in Tissues

The field of tissue engineering is rapidly progressing, in large part thanks to hydrogel scaffolds that provide a comfortable home for new cells. A major issue that researchers bump against is tracking how well oxygen reaches freshly grown cells within such scaffolds, which can indicate how well the new cells are generally functioning. Now, researc (Read more...)

Generating Hallucinations Using Optogenetics

About a decade ago, Karl Deisseroth of Stanford University developed a technology called optogenetics. It allows scientists to stimulate individual nerve cells using light beams within the brains of live and moving animals. Now, this technology has been used to generate visual hallucinations within lab mice, causing them to act as though the things (Read more...)

New High-Res Holographic Microscope to Study Live Cells

Nanolive, a spinoff company of École polytechnique fédérale de Lausanne (EPFL) in Switzerland, has just introduced a holographic microscope that can image live cells at high resolution over extended time periods. Nanolive’s CX-A device relies on a low energy light beam to penetrate the sample, which does not interfere wit (Read more...)