Tag: Genetics

Acoustofluidics Pulls Exosomes from Whole Blood

Exosomes are tiny vesicles that are released by the body’s myriad of cells and that are found in blood, urine, and other bodily fluids. Their role within our bodies is still largely a mystery, but there’s already considerable evidence that they may be biomarkers of disease and indicators that certain processes are happening within the [ (Read more...)

New Material With Live Cells for Organ, Tissue Printing

At the University of British Columbia (UBC) in Canada researchers have developed and tested a new bio-ink that may serve as a critical building block for manufacturing replacement tissues and organs. The technology will hopefully speed up the quest to heal a great deal of conditions and diseases by implanting perfectly healthy body parts in [&helli (Read more...)

Quantum Dots Light Up Tumors Brighter Than Ever Before

Scientists at the Sanford Burnham Prebys Medical Discovery Institute (SBP) in San Diego, California have devised a way to optically image tumors with unprecedented clarity using quantum dots. These nano structures are tiny particles, only a few nanometers wide, that generate light of a specific wavelength when they’re themselves stimulated by (Read more...)

Nanocages Made of DNA Strands Release Small Molecules to Improve Challenging Studies Inside Body

Many of the activities happening within our bodies are incredibly difficult to study, as some happen in hard to reach places and their timespan is very short. The action of neurosteroids, chemicals that perform an important role in the lives of neurons, is one such topic. Neurosteroids take less than a second to act, and getting anywhere (Read more...)

Nanoparticles to Deliver mRNA: Just Add Water

Scientists at the Fred Hutchinson Cancer Research Center in Seattle, Washington have developed a nanoparticle messenger RNA (mRNA) delivery system to temporarily change gene expression in treated cells. Growing specific cell types in a lab and then administering them to patients is the goal of cell therapies, and these types of treatments are comin (Read more...)

Technique to Produce Multi-Target Antibody Therapies

Researchers in The Netherlands and Switzerland have devised a new technique to reliably produce antibodies that can bind to two different target molecules at the same time, which could be very useful for cancer immunotherapy. Antibodies are Y-shaped protein structures that can recognize and bind to highly specific target molecules at the tip of eac (Read more...)

Scientists Use Light to Erase Unwanted Memories

Researchers at the University of California, Riverside have developed a technique to selectively erase fear memories by weakening connections between the nerve cells involved in forming such memories. Memories can be triggered by stimuli such as sights, sounds, and smells. Some memories are formed during traumatic events, and in this case stimuli a (Read more...)

Growing and Testing Drugs on Dozens of Tiny Guts at Once

In a demonstration of where the field of organ-on-a-chip technology is inevitably going, MIMETAS, a company developing organ-on-chip technology out of Leiden, The Netherlands, and Roche, the giant pharmaceutical company, teamed up to grow and test 350 perfused gut tubes within a matter of days. The gut tubes replicate the basic structure of an (Read more...)

Miniature Bioengineered Vessels to Study Progeria Therapies

Progeria is a rare but deadly disorder that is commonly known as an early aging disease, bringing forth conditions in children that are normally only reserved for older adults. To better study how to fight progeria, a disease that significantly affects the cardiovascular system, researchers at Duke University have developed a way to grow tiny [&hel (Read more...)

Injectable Tissue Patch to Fix Broken Hearts

Scientists at the University of Toronto have developed a bandage-like patch that can be delivered into the heart through a needle, in combination with stem cells allowing for minimally invasive cardiac tissue repair, currently an impossible task. After a massive heart attack, myocardial tissue damage can significantly reduce the cardiac output. One (Read more...)

New Probe to Safely Measure pH Inside Living Cells

An unusually acidic environment around living cells may be an indicator that processes associated with disease are taking place in the vicinity. Of course there’s a myriad of other biological variables related to the cellular pH. To measure the cellular pH levels, fluorescent dyes exist that glow when illuminated by a specific wavelength of l (Read more...)

Smartphone-Powered Diagnostic Spectrum Analyzer Shrinks a Hospital Lab Into Portable Device

Bioengineers at the University of Illinois at Urbana-Champaign have turned a smartphone into a portable diagnostic laboratory capable of performing a range of spectrum analyses that is currently done using large and expensive stationary machines. The investigators built a smartphone attachment that utilizes the smartphone’s camera to analyze (Read more...)