Tag: Genetics

Scientists Develop Accurate Model of Blood-Brain Barrier

The blood-brain barrier (BBB) is the primary reason that so few medicines exist to treat brain conditions. Drugs that can attack tumors elsewhere usually can’t penetrate the defenses of the BBB, so figuring out how to get through it is important for the development of future drugs and other therapies. There have been attempts to […]

Liquid Biopsy for Monitoring Transplanted Stem Cells

Researchers from the University of Maryland, University of Pennsylvania, and Emory University have demonstrated that a blood test can be used to track the efficacy of transplanted stem cells. They analyzed tiny cellular components called exosomes that were secreted from transplanted stem cells. “Exosomes contain the signals of the cells they& (Read more...)

3D Printed ELISA Pipette Tips for Low Cost Medical Testing

Researchers at the University of Connecticut have developed a 3D printed enzyme-linked immunosorbent assay (ELISA) device, which fits onto a normal pipette and substantially reduces the time and cost of this common medical test. The device could allow for medical testing in remote or low-resource regions, where such tests would otherwise be unavail (Read more...)

Synthetic Proteins Designed to Halt Growth of Cancers

Stanford University scientists have developed a novel approach to halting the growth of cancer cells while preserving normal function in healthy cells. The research was published in journal Science, and though it was so far conducted only on groups of cancer cells outside a body, the findings are incredibly promising. The new approach focuses on [& (Read more...)

Intestine Chip to Study Human-Microbiome Interactions

Researchers at the Harvard Wyss Institute have developed a microfluidic chip that allows bacteria and human epithelial cells to be co-cultured. The device will allow researchers to study how the gut and bacteria interact, helping them to identify the role of the microbiome in health and disease. With reported involvement in a huge array of [&hellip (Read more...)

Material Made from DNA Undergoes Metabolism, Powers Itself

Scientist at Cornell University have developed a remarkable new material, which is made out of DNA and which undergoes metabolism. One of the crucial aspects of life is metabolic activity, which essentially means that large molecules are broken down and small molecules are used to build larger ones. The dynamic material that the Cornell team [&hell (Read more...)

Engineered Matrix to Improve T Cell Immunotherapy

Researchers from Johns Hopkins University have developed an “artificial lymph node” to help multiply antigen-specific T cells to fight cancer. They used a hydrogel that contains immunostimulatory antigen-presenting nanoparticles to encourage T cells to proliferate, and have increased activity against specific antigens. Current T-cell ba (Read more...)

3D-Printed Heart From Patient’s Own Tissues

Researchers from Tel Aviv University in Israel have developed a 3D printing approach to create a heart with a patient’s own cells. The investigators used patient-derived cellular and acellular material obtained from fatty tissue, along with a unique bioprinter, to 3D-print a heart. The team isolated cells from a patient tissue sample and used (Read more...)

CRISPR-Chip Can Detect Genetic Mutations Within Minutes

Researchers at the University of California, Berkeley and the Keck Graduate Institute of The Claremont Colleges have developed a hand-held device that can detect genetic mutations, such as those causing genetic diseases or affecting how people respond to certain drugs, in just minutes. The device employs a combination of CRISPR and graphene transis (Read more...)