Tag: Genetics

Complex Brain Organoids to Help Study Neuro Diseases and Cures

At the Salk Institute in La Jolla, California, researchers have been building 3D models of bits of living brain. In a new study appearing in Nature Biotechnology, the investigators have now come up with a technique for delivering oxygen to these organoids, growing them into more complex units, and transplanting them into living rodents. The [&helli (Read more...)

Rendering Brain Tissue Transparent with OPTIclear to Unlock Secrets of Alzheimer’s and Parkinson’s

Researchers from Imperial College London and The University of Hong Kong have published results in Nature Communications of a revolutionary process that renders human brain tissue transparent and allows the complex network of neurons to be mapped. This technique of clearing alters brain tissue’s optical properties without impacting the cell s (Read more...)

Cardiomyocyte Molds to Improve Cardiac Cell Therapy

Researchers at Michigan Tech and Harvard Medical School have developed a new way to create cardiomyocytes from induced pluripotent stem cells (iPSCs), for improved cardiac cell therapy. The team developed a culture mold that mimics the physiological conditions under which cardiomyocytes grow. When the team tested the molds, they found that the cell (Read more...)

Interview with Devyn Smith PhD, COO of Sigilon Therapeutics

Sigilon Therapeutics is a Cambridge, MA-based biotech company developing innovative therapeutics by encapsulating cells in a novel coating that renders them invisible to the immune system. The engineered cells contained in the company’s particles can provide long-term continuous therapy for a range of chronic disorders, including hemophilia a (Read more...)

Peptide Hydrogel Promotes Tissue Growth to Heal Without Drugs

Rice University researchers studying how different drugs, proteins, and cells embedded in peptide hydrogel can boost healing and promote tissue formation, discovered that the hydrogel itself exhibits powerful therapeutic properties. Their self-assembling multidomain peptide (MDP) with the amino acid sequence K2(SL)6K2 can be injected into tiss (Read more...)

Liquid-Powered Bioprinting of Tissues at Any Scale

Researchers at Queen Mary University of London, University of Oxford, and Nanyang Technological University in Singapore, have developed an unusual way to print complex biological structures with multiple ingredients that can harness further tissue growth. The 3D structures that are created are made of modular components that can be brough (Read more...)