Tag: Materials

Improved Membrane Coating for Anti-Cancer Nanoparticles

Scientists at the University of Eastern Finland have developed a technique that lets them improve the coating of nanoparticles when using cell membranes. Cell membranes offer a lot of benefits as a coating for synthetic nanoparticles, including shielding from the immune system, prolonged circulation times and improved tumor accumulation. However, c (Read more...)

Electrospun Construct Mimics Elasticity of Blood Vessels

Researchers at the University of Sydney in Australia have developed an electrospun blood vessel replacement. The material contains tropoelastin, a natural precursor for elastin, a key component of blood vessel walls. Elastin is present in concentric circles in natural blood vessels and provides the elastic properties which allow them to distend sli (Read more...)

Flexible Sensors Measure Fit of Face Masks

Researchers at MIT have developed a sensor system that can provide data on how well a face mask fits to a wearer’s face. The protection offered by a mask is largely dependent on how well it fits the face, but at present most face masks are one-size-fits-all and most wearers are largely unaware if their […]

3D Bioprinted Breast Tumors for Immunotherapy Testing

A team of scientists at Penn State has bioprinted breast tumor mimics with significant complexity, including a form of vascularization and the ability to precisely place cells in certain locations within the construct. The scientists used a technique called aspiration-assisted bioprinting to achieve this. With many anti-cancer therapies failing at (Read more...)

Low Temperature Graphene Coating for Enhanced Wearables

Researchers at Caltech came up with a technique to coat flexible electronic circuits with graphene to enhance their durability on folding, as well as to improve their resistance to sweat (in the case of graphene-coated gold) and their conductivity. The method could enhance the flexible electronics that are employed in many medical wearables. The ap (Read more...)

AI-Designed Custom Knee Implants

Scientists at the University of Birmingham in the UK have trialed Generative Design, a design approach that relies on machine learning and artificial intelligence, to create patient-specific knee implants. At present, knee implants are typically created in a limited range of sizes and shapes. While 3D printing has opened some scope for implants tha (Read more...)

DNA Nets Capture Sars-CoV-2 for Detection and Inhibition

A team at the University of Illinois at Urbana-Champaign has developed a DNA net system that can ensnare Sars-CoV-2 and bind to the notorious spike protein. The nets contain aptamers that bind the spike protein and emit an intense fluorescent signal once they’re bound together to the protein. This signal can be easily measured using [… (Read more...)

Soft Robot Grows Like a Plant to Travel Through Tight Spaces

At the University of Minnesota, researchers have developed a soft robotic system that can ‘grow’ like a plant. The mechanism allows it to travel through difficult-to-access areas, such as the tortuous gastrointestinal tract or vasculature. The system works by extruding a liquid through an opening in the device, and at the same time a ph (Read more...)

Algae-Based Microrobots Deliver Antibiotics within Lungs

Researchers at the University of California San Diego have developed a microrobot system to treat bacterial pneumonia. The microrobots consist of living algal cells that can swim very effectively in biological fluids, allowing them to navigate throughout the lungs and deliver drugs to difficult-to-reach areas. The algal cells are studded with antib (Read more...)

Soft Robot Biodegrades Inside Body

Researchers at the City University of Hong Kong have developed a magnetic soft millirobot that can grab and release objects, and move around by rolling. The device can be controlled using magnetic fields, and consists of a biodegradable gelatin and iron oxide microparticles. The technology has significant potential as a minimally invasive drug deli (Read more...)

Granular Hydrogels for Improved Bioinks

Researchers at Penn State have developed a granular hydrogel that contains both hydrogel microparticles and self-assembling nanoparticles, and which could be highly suited for bioprinting purposes. The concept involves the nanoparticles becoming adsorbed onto the hydrogel microparticles and reversibly adhering the microparticles together, providing (Read more...)

Surface Coating Rapidly Kills Pathogens, Lasts Months

A team at the University of Michigan has developed a coating for frequently touched surfaces that can rapidly kill a wide array of pathogens, including MRSA and SARS-CoV-2. The technology incorporates polyurethane that contains crosslinked compounds from essential oils with wide-spectrum anti-microbial action. The researchers fine-tuned the crossli (Read more...)

EEG Caps for Brain Organoids

Researchers at Johns Hopkins University have created tiny EEG caps for brain organoids. The team was inspired by full size EEG caps that are used to measure brain activity in human patients. Previously, the Hopkins researchers were forced to use flat electrode arrays that were originally designed to take recordings from cell monolayers, but applyin (Read more...)

Bioengineered Cornea Restores Sight

Scientists at Linköping University in Sweden have developed a collagen-based corneal implant that can restore sight to blind patients with corneal disease. The breakthrough could pave the way for such patients to receive effective treatment for corneal disease without requiring a corneal transplant from a human donor. There is a shortage of do (Read more...)

Tough Ultrasound-Controlled Bioadhesives

Scientists from McGill University in Canada created a technique of using ultrasound-mediated cavitation to make bioadhesives better stick to body’s tissues, including wet surfaces that are typically challenging for such materials. The new method involves ultrasound to create microbubbles within the adhesive. The bubbles burst, which then temp (Read more...)

Light-Activated Hydrogel Disrupts Oral Biofilms, Whitens Teeth

Researchers at Nanchang University in China developed a photodynamic hydrogel treatment for teeth that disrupts bacterial biofilms, helps to prevent cavities, and whitens teeth. The gel is applied to the teeth and is then activated using green light, which is less harsh on nearby skin than the high intensity blue light that is sometimes used [&hell (Read more...)