Researchers at the University of Pennsylvania’s School of Medicine have developed a new method for sequencing chemical groups attached to the surface of DNA. These chemical groups are modifications of the DNA bases that convey important information relating to the patterns of gene expression. These modifications have been studied for the past (Read more...)
Tag: Pathology
Applied BioCode’s MDx-3000 Cleared for GI Pathogen Detection
Applied BioCode, a company based in Santa Fe Springs, California, landed FDA clearance for its BioCode MDx-3000 molecular system for testing for 17 common gastrointestinal pathogens, including bacteria, viruses, and parasites. Clearance was based in part on a multi-center clinical study involving over 1,500 samples. The device is intended (Read more...)
Glow-In-The-Dark Paper Test Rapidly Detects Infectious Diseases
Researchers at Eindhoven University of Technology in The Netherlands and Keio University in Japan have developed a paper-based diagnostic test, which can be used to rapidly and inexpensively test for a variety of infectious diseases. A clinician can apply a drop of blood to the paper strip and detect the color of the emitted light […]
Proscia Raises $8.3M Series A to Expand AI-Driven Digital Pathology Platform
This week, Proscia, a Philadelphia-based digital pathology company started by entrepreneurs from Johns Hopkins University and the University of Pittsburgh, announced the completion of an $8.3 million Series A financing led by Flybridge Capital Partners. Other participants in the round included Emerald Development Managers, Fusion Fund, Razor’ (Read more...)
Proscia Raises $8.3M Series A to Expand AI-Driven Digital Pathology Platform
This week, Proscia, a Philadelphia-based digital pathology company started by entrepreneurs from Johns Hopkins University and the University of Pittsburgh, announced the completion of an $8.3 million Series A financing led by Flybridge Capital Partners. Other participants in the round included Emerald Development Managers, Fusion Fund, Razor’ (Read more...)
Science Fiction Inspired Handheld Diagnostic Device
A team of researchers at Glasgow University, UK have developed a portable rapid diagnostic device that could be used to detect a number of conditions, including cancer and cardiovascular disease. Inspired by the famous Star Trek medical tricorder, the research team behind the innovation set out to create a “multicorder” device. The (Read more...)
Smartphone App and Portable Lab Kit Can Rapidly Detect Pathogenic Bacteria
Researchers at UC Santa Barbara have developed a point-of-care diagnostic kit that can detect pathogenic bacteria in patient samples in as little as one hour. The technology is inexpensive and portable. It consists of a small box of basic lab equipment and a smartphone, that can achieve sensitive and specific identification of a variety of [&hellip (Read more...)
Deep Convolutional Neural Network Identifies Lung Cancer Types from Biopsy Slices
Many of us think of artificial intelligence (AI) as computers mimicking humans in thinking and behavior. Thankfully, the reality is still very different and AI is more of an evolving tool that can tackle narrow tasks that humans are otherwise not good enough at. One of those tasks is looking at complex images of tissue […]
Precipio Announces ICEme Kit for Lung Cancer Mutation Detection
Earlier this year, Medgadget heard from Precipio CEO Illan Danieli on how his company uses advanced diagnostics and personalized medicine to reduce the prevalence of cancer misdiagnosis. Over 1 million patients globally and about 200,000 patients in the U.S. are annually diagnosed with non-small cell lung cancer (NSCLC). This week, t (Read more...)
New Faster, Cheaper, Better Test Platform for Nucleic Acid Identification of Diseases
At the National University of Singapore, scientists have developed a portable, point-of-care nucleic acid test platform that can be used to diagnose a variety of diseases. It comes in the form of a cartridge that does not need to be kept refrigerated or handled specially in any other way and once used it provides results faster […]
Paper Test for Monitoring Phenylalanine and Other Metabolites in Blood
People with congenital phenylketonuria, a condition in which the amino acid phenylalanine is overproduced, have to undergo regular blood testing. This is important in part because maintaining a proper diet can reduce phenylalanine levels, so gauging the effectiveness of one’s diet can help control the condition. Currently, though, blood (Read more...)
Looking Deep Into Living Brain Using Photon Counter on Laser Scanning Microscope
New technology has been developed at Tel Aviv University in Israel that significantly improves 2D and 3D imaging of neuronal activity in the brains of living animals. The technology should help make new findings possible about the workings of the brain and how neurological diseases operate. PySight, as the technology is called, uses open-source sof (Read more...)
Deton is Developing “Aerosol Biopsy” to Detect Lung Diseases
Biopsies and bronchoscopies are the gold standard for diagnosing lung diseases, including pneumonia and cancer. However, these procedures are difficult to provide, requiring general anesthesia and an operating room. Deton hopes to simplify the process. The Pasadena-based company takes advantage of the lung’s natural reaction to bacteria or pa (Read more...)
Immunexpress Saving Lives with Improved Sepsis Diagnosis: Interview with Rolland Carlson PhD, CEO
Sepsis is the overwhelming response of the body’s immune system to infection, leading to life-threatening tissue and organ damage. The condition is poorly understood, hard to diagnose, and currently kills 30-50% of those with a confirmed diagnosis in the developed world and 60-80% of those diagnosed in developing countries. Sepsis is estimate (Read more...)
HP’s BioPrinters Going to Work to Fight Antibiotic Resistance
The Centers for Disease Control and Prevention (CDC) has partnered with HP to use the company’s new BioPrinters to test bacterial pathogens for resistance to specific antibiotic samples. The HP D300e Digital Dispenser BioPrinters are being used as part of the Antibiotic Resistance Lab Network to create better tools to address develo (Read more...)
Legos, Smartphone, and Novel Chemicals Unite to Detect Nerve Agents
Though nerve attacks are, thankfully, very rare, when they do happen first responders need a way to quickly identify the agent that was used. Researchers at University of Texas at Austin have brought together both simple and advanced technologies to create a system for detecting nerve agents such as VX and sarin. Previously, members of […]
Paper Test Spots Fake Antibiotics
Antibiotics are some of the most commonly faked medications out there, plus many end up being diluted before reaching patients. Though this is unusual in richer countries, it is a serious problem in less well off places. To help address this issue, researchers at Colorado State University have created a paper-based test that can quickly […]
New Device for Studying Bacterial Biofilm Formation
Biofilms are large groups of bacterial cells that stick together and protect each other like a Roman legion. Drugs and other therapies can poke at the exterior of a biofilm, but killing the mass can be extremely challenging. Researchers at the Okinawa Institute of Science and Technology in Japan decided to look more closely at the […]
Custom 3D-Printed Microfluidics for Cell-Based Health Research
Researchers at NYU Abu Dhabi (yes, there is such a thing) have developed a method to 3D print functional and inexpensive microfluidic probes for cancer research. The technique could make microfluidics more accessible, allowing researchers to easily design and produce their own devices, and conduct cell-based healthcare research, such as studying ca (Read more...)
Twisters Inside a Lab-on-a-Chip Trap Viruses, DNA, Biomolecules
At Purdue University engineers have developed a new type of optical nanotweezers that can be used to grab onto and inspect viruses, DNA strings, and other important biomolecules. The innovative lab-on-a-chip device relies on a “nanostructured plasmonic metafilm” created out of a very thin gold sheet with nano-scale holes drilled into it (Read more...)