Tag: Pathology

3D Printed Microscope Costs as Little as $18

Researchers at the University of Bath in the UK have developed a 3D-printed microscope design, called OpenFlexure, which is open-source and can be assembled for as little as $18. More complex versions of the design are possible, and the microscope can incorporate full automation and a Raspberry Pi computer. The research team hopes that the [&hellip (Read more...)

Micro-OCT Lets Docs Spot Tumors Below Tissue Surface

A collaboration between researchers at Nanyang Technological University, Harvard Medical School, and University of Alabama has led to the development of a prototype device capable of imaging through tissues at resolutions down to 1 micrometer (μm). The micro-OCT imager takes advantage of optical coherence tomography (OCT) at wavelengths between (Read more...)

Magnetic Beads Trap E. Coli from Body Fluid Samples

While current concern is all about the COVID-19 virus that originated in China and spread around the world, this pathogen will eventually disappear. Escherichia coli (E. coli) bacteria, though, is with us for the long run and it can cause just as much suffering as COVID-19. Researchers at Rutgers University have just reported in journal […]

Table-Top Robot Uses AI to Make Blood Draws, Insert Catheters

Researchers at Rutgers University have developed a robot that utilizes artificial intelligence, along with near-infrared and ultrasound imaging, to automatically make blood draws and insert catheters in small blood vessels. The device could take the guesswork out of blood draws, which are frequently challenging when performed manually, and reduce t (Read more...)

Point-of-Care HIV Diagnostics for Low Resource Regions: Interview with Jesse Lehga, VP at Diagnostics for the Real World

DRW (Diagnostics for the Real World), a company with headquarters in San Jose, California, and Cambridge, United Kingdom, has developed the SAMBA II, a point-of-care diagnostic device for the detection of infectious diseases, including HIV and HCV, for use in low-resource and/or remote regions. The system employs nucleic acid amplification to detec (Read more...)

Hybrid Infrared-Optical Microscope for Pathology Studies

When imaging tissues microscopically, pathology labs have to stain the samples to see the cellular shapes and structures within. This is not trivial and requires expertise, time, and related costs. Infrared light has the capability to help visualize biomedical samples without staining, but the wavelengths of such light make it incompatible with opt (Read more...)

Pill-Sized Chemical Heater for Point-of-Care Diagnostic Tests

Researchers at the University of Toronto have developed a miniaturized chemical heater that can precisely heat biological samples during diagnostic tests, but does not require electricity or any specialized equipment to work. The low-cost technology is based on the exothermic reaction that occurs when lithium encounters water, and the precise shape (Read more...)

Lensless Microscopy Chip for Diagnostic Applications

Researchers at the University of Connecticut have developed a lensless microscope that allows an observer to enjoy an enormous field of view. Instead of a lens, the system relies on a diffuser that lies between the object being imaged and the camera sensor. This novel technology could greatly help clinicians to assess diagnostic tissue samples [&he (Read more...)

Lensless Microscopy Chip for Diagnostic Applications

Researchers at the University of Connecticut have developed a lensless microscope that allows an observer to enjoy an enormous field of view. Instead of a lens, the system relies on a diffuser that lies between the object being imaged and the camera sensor. This novel technology could greatly help clinicians to assess diagnostic tissue samples [&he (Read more...)

Credit Card Sized Diagnostic Lab Plugs into Smartphone

Researchers at the University of Cincinnati have developed a tiny portable diagnostic device that can detect the presence of specific pathogens in a saliva sample, and relay the results to a doctor when plugged into a smartphone. The device can potentially diagnose a wide array of diseases, including malaria, HIV and Lyme disease, and could [&helli (Read more...)

Genomic Profiling for Precision Medicine: Interview with David Spetzler, Caris Life Sciences

Caris Life Sciences, a Dallas-based innovator in molecular science focused on fulfilling the promise of precision medicine, has developed the MI Genomic Profiling Similarity (GPS) score to compare the molecular characteristics of specific tumors against those in the Caris database. This allows clinicians to identify the molecular subtype of their p (Read more...)

Device Links Up to 10 Organ Chips to Form Body-on-a-Chip

Researchers at the Harvard Wyss Institute have developed a “body-on-a-chip” consisting of up to 10 organ-on-a-chip devices that are linked together to mimic blood flow between different organ systems. The new system allows for more comprehensive drug testing, enabling researchers to see the effects of a drug on multiple organ systems si (Read more...)

Antimicrobial Layer for Plastic Food Wrap Developed

Bacteria can take a ride and proliferate on the plastic wrap that foods are commonly packaged in. Researchers at Penn State have developed a way to bond a non-toxic transparent antimicrobial material to the ubiquitous polyethylene wrap that meats, vegetables, and mushrooms are sold in. The antimicrobial layer is made of a pullulan-based biopolymer, (Read more...)