Tag: Pathology

Chip to Evaluate Health of Immune System from Blood Sample

Knowing how well a patient’s immune system is functioning may be very useful in diagnosing a disease and guiding the course of therapy. Researchers from Nanyang Technological University in Singapore are making this a reality, having developed a hybrid chip that assesses the health of white blood cells in a whole blood sample. The microfluidic (Read more...)

3D Liquid-Cell Electron Microscopy Imaging Now Possible

Electron microscopy revealed a world that exists at scales smaller than the wavelength of light. Advancements in this field have allowed scientists to visualize ever more objects and processes, but actually seeing living cells in 3D and within a liquid environment has been impossible. Now, a team of researchers from Penn State University, Virginia (Read more...)

Microfluidic Device for Rapid Lyme Disease Diagnosis

Researchers at Columbia University have developed a microfluidic device that can diagnose Lyme disease in as little as 15 minutes. The device is particularly accurate in identifying antibody biomarkers that are present during early stage Lyme disease, raising hopes that it could be useful in detecting cases of early infection in a doctor’s of (Read more...)

New Chip for Microwave Imaging of Body

Today’s clinicians are limited to a few imaging modalities, primarily X-ray, CT, MRI, and ultrasound. Microwaves, in principle, can also be used as a useful way to look inside the body. Microwave radiation is non-ionizing, so should be safer than X-rays, but in practice microwave imagers, because of the electronics inside, have remained bulky (Read more...)

Hydrogel Mimics of Heart Tissue to Study Cardiac Reshaping Following Aortic Valve Implantation

Transcatheter aortic valve replacement (TAVR) procedures have become a popular way of treating aortic valve stenosis, a condition in which the valve stiffens and worsens cardiac function. Following implantation of a prosthetic valve, the hearts of patients tend to undergo significant reconstruction around the treatment site, but the mechanics of th (Read more...)

Minimally Invasive Biopsies Provide Maximum Pathology Data

Current pathology techniques for analyzing biopsy tissues are lacking in their ability to detect cancer in small samples. Being able to rapidly study the distribution of protein expression within cells, gathered from minuscule samples, could be an important tool for early diagnosis and monitoring of cancer. Now, researchers at National University o (Read more...)

Diagnostic Pill Samples Bacteria While Traveling Inside Gut

The microbiome inside our gut contains a wide variety of bacterial species, some of which are a source of disease. Currently, only the lower intestine can be sampled non-invasively to learn about the bacterial flora within, so there’s actually little knowledge about what goes on higher up the GI tract. Researchers at Tufts University have [&h (Read more...)

New Infrared Chemical Imaging Method to Diagnose Cancers

Prostate cancer can be very difficult to diagnose, with way too many patients undergoing surgeries that turn out to be unnecessary. Now, researchers at Purdue University, Boston University, and the Chinese Academy of Sciences have developed an infrared chemical imaging technique that may improve diagnostic studies and in the process cut down on exc (Read more...)

CompCyst Tool Developed to Identify Precancerous Cysts

Researchers from Johns Hopkins Kimmel Cancer Center have developed a new computational and biomolecular tool, dubbed CompCyst, that can identify precancerous pancreatic cysts. The technology provides a new method for reliably identifying cancer-causing cysts from those that are not cancer-causing. The teams work demonstrates that in over half of pa (Read more...)

New High-Res Holographic Microscope to Study Live Cells

Nanolive, a spinoff company of École polytechnique fédérale de Lausanne (EPFL) in Switzerland, has just introduced a holographic microscope that can image live cells at high resolution over extended time periods. Nanolive’s CX-A device relies on a low energy light beam to penetrate the sample, which does not interfere wit (Read more...)