Tag: Pathology

Smart Microscope Learns to Diagnose Infectious Diseases

Experienced professionals tend to be better than rookies partly because they know how to use the tools of their trade more effectively. Cytologists who evaluate cells under a microscope become more consistent and accurate when they know how to prep their apparatus to produce clear images. Researchers at Duke University have now given a microscope [ (Read more...)

Low Cost Turbidity Measurements Using a Fitness Tracker

Continuous monitoring of bacterial growth is a critical step in the biotechnology industry and in biological labs. These measurements are typically taken using large and bulky spectrophotometers that do not fit into incubators for real-time monitoring. Moreover, continuous monitoring is labor-intensive as it requires multiple samplings. Recent deve (Read more...)

Controllable Microswimmers Move Around Individual Cells in 3D

Manipulating individual cells and microscopic particles may be extremely valuable for testing new therapies, targeting tumors, and for studying the underlying causes of disease, but it is very difficult to directly manipulate individual cells within an environment shared with other cells. A collaboration of researchers from University of California (Read more...)

Tiny Medical Imaging Sensor Sets Guinness World Record

OmniVision Technologies, a Santa Clara, California firm, just announced that it has won the Guinness World Record for “The Smallest Commercially Available Image Sensor”. The OV6948 sensor was designed for use in catheters and endoscopes, allowing these devices to be as small as possible while also providing high quality imaging from wit (Read more...)

Chip to Evaluate Health of Immune System from Blood Sample

Knowing how well a patient’s immune system is functioning may be very useful in diagnosing a disease and guiding the course of therapy. Researchers from Nanyang Technological University in Singapore are making this a reality, having developed a hybrid chip that assesses the health of white blood cells in a whole blood sample. The microfluidic (Read more...)

3D Liquid-Cell Electron Microscopy Imaging Now Possible

Electron microscopy revealed a world that exists at scales smaller than the wavelength of light. Advancements in this field have allowed scientists to visualize ever more objects and processes, but actually seeing living cells in 3D and within a liquid environment has been impossible. Now, a team of researchers from Penn State University, Virginia (Read more...)

Microfluidic Device for Rapid Lyme Disease Diagnosis

Researchers at Columbia University have developed a microfluidic device that can diagnose Lyme disease in as little as 15 minutes. The device is particularly accurate in identifying antibody biomarkers that are present during early stage Lyme disease, raising hopes that it could be useful in detecting cases of early infection in a doctor’s of (Read more...)

New Chip for Microwave Imaging of Body

Today’s clinicians are limited to a few imaging modalities, primarily X-ray, CT, MRI, and ultrasound. Microwaves, in principle, can also be used as a useful way to look inside the body. Microwave radiation is non-ionizing, so should be safer than X-rays, but in practice microwave imagers, because of the electronics inside, have remained bulky (Read more...)

Hydrogel Mimics of Heart Tissue to Study Cardiac Reshaping Following Aortic Valve Implantation

Transcatheter aortic valve replacement (TAVR) procedures have become a popular way of treating aortic valve stenosis, a condition in which the valve stiffens and worsens cardiac function. Following implantation of a prosthetic valve, the hearts of patients tend to undergo significant reconstruction around the treatment site, but the mechanics of th (Read more...)

Minimally Invasive Biopsies Provide Maximum Pathology Data

Current pathology techniques for analyzing biopsy tissues are lacking in their ability to detect cancer in small samples. Being able to rapidly study the distribution of protein expression within cells, gathered from minuscule samples, could be an important tool for early diagnosis and monitoring of cancer. Now, researchers at National University o (Read more...)