Researchers at Eindhoven University of Technology in the Netherlands have developed a sensitive diagnostic test for viral pathogens that is suitable for use in low-resource regions. The test is based on CRISPR proteins that can detect viral genetic material but also incorporates luciferase proteins, which are bioluminescent proteins that are natura (Read more...)
Tag: Public Health
HIV Vaccine Candidate Stops Virus As it Enters Body
Researchers at the Texas Biomedical Research Institute are developing a vaccine candidate against HIV. The vaccine is intended to block HIV entry into the body and is administered to the mucosal lining of the rectum and vagina to achieve this. The formulation then stimulates antibodies against HIV in precisely the areas where the virus first [&hell (Read more...)
Electrostatic Face Mask Self-Charges with Breathing
Researchers at City University of Hong Kong have developed an electrostatically charged face mask that can replenish its charge through the wearer’s breathing action. The electrostatic charge helps the mask to adsorb tiny particles, such as SARS-CoV-2 viruses. However, such masks typically lose their charge and ability to bind particles over (Read more...)
NextGen COVID-19 Antibodies Destroy Spike Protein
Researchers at the Garvan Institute of Medical Research in Australia have developed a new generation of antibodies to treat COVID-19. So far, the antibodies have been shown to neutralize several of the viral variants behind COVID-19, and the researchers hope that they will form an effective treatment for at-risk patients. Previously developed antib (Read more...)
Automated Feeding Platform to Study Mosquito Disease Transmission
A team at Rice University has developed an automated feeding platform for mosquitoes that allows researchers to test different types of repellent and investigate mosquito-borne disease transmission. Traditionally, such mosquito research would require human volunteers or animal subjects for the mosquitos to feed on, but this is obviously inconvenien (Read more...)
Electrochemical Sensor for Detailed SARS-CoV-2 Immunity Data
Researchers at the Harvard Wyss Institute have developed an electrochemical device, called the eRapid sensor, that can assist clinicians in quickly characterizing someone’s COVID-19 infection, including identifying the infecting viral variant and the nature of someone’s immunity to the virus in terms of whether it is vaccine-mediated or (Read more...)
Voice-Activated Sample Prep for Safer Handling
Researchers at Kyung Hee University in South Korea have developed a voice-activated DNA sample pre-treatment device to assist clinicians dealing with outbreaks of infectious disease to stay safer. Dealing with highly infectious patient samples puts clinicians and lab technicians at risk. Minimizing sample handling and exposure is important in reduc (Read more...)
Toolbox to Study Ligand Binding for Enhanced Treatments
Researchers at Ecole Polytechnique Fédérale de Lausanne (EPFL) in Switzerland have developed a DNA toolbox that allows researchers to explore binding interactions between ligands and their respective receptors based on receptor density and arrangement. The basis for many pharmacological interactions between drugs and cells, and indeed (Read more...)
Ferrobot Swarms for Rapid Viral Testing
At the University of California Los Angeles, scientists have developed a handheld lab kit that can conduct automated pooled testing for viral diseases, including COVID-19. The technology consists of a microfluidic platform that relies on swarms of magnetic discs, which the researchers have termed “ferrobots”, to shuttle samples through (Read more...)
Micelle Technology Detects Airborne SARS-CoV-2
At the Pacific Northwest National Laboratory, researchers have developed micelle technology that can detect minute amounts of SARS-CoV-2 in the air. This new capability could provide invaluable monitoring systems to detect viral contamination in healthcare facilities and beyond. Micelles are somewhat similar to liposomes in that they are both like (Read more...)
Flexible Sensors Measure Fit of Face Masks
Researchers at MIT have developed a sensor system that can provide data on how well a face mask fits to a wearer’s face. The protection offered by a mask is largely dependent on how well it fits the face, but at present most face masks are one-size-fits-all and most wearers are largely unaware if their […]
Neck Sensor Helps Masked Clinicians Communicate
Researchers at Pohang University of Science & Technology in South Korea developed an auditory sensor that lets people wearing face masks, such as clinicians, to communicate more easily. The device is essentially a wearable microphone that picks up the vibrations of the skin in the neck that occur when someone talks. The researchers hope that [& (Read more...)
mRNA Therapy Prevents COVID Virus Entering Cells
Scientists at Oregon State University have developed a new treatment for COVID-19. The technology is based on mRNA, which has also been put to good use in COVID-19 vaccines. However, in this instance, the delivered mRNA encodes for human angiotensin-converting enzyme 2 (hACE2), which is the binding site for SARS-CoV-2 on airway cells. The lipid [&h (Read more...)
Screening App to Diagnose Parkinson’s, COVID-19 from Voice
Researchers at RMIT University in Melbourne, Australia, have developed an app that is intended to provide early diagnosis for Parkinson’s disease and severe COVID-19. The artificial intelligence-powered technology works by analyzing voice recordings, having previously been trained to recognize the vocal hallmarks of these diseases by listenin (Read more...)
CRISPR-Cas13 System for Quick and Sensitive SARS-CoV-2 Detection
Scientists at Rice University created a rapid COVID-19 test that is based on the gene editing CRISPR-Cas system. The researchers modified the Cas-13 protein to increase its activity and to light up with fluorescence when it encounters RNA from the virus. The system does not require the expensive lab equipment and technical expertise of PCR, [&helli (Read more...)
DNA Nets Capture Sars-CoV-2 for Detection and Inhibition
A team at the University of Illinois at Urbana-Champaign has developed a DNA net system that can ensnare Sars-CoV-2 and bind to the notorious spike protein. The nets contain aptamers that bind the spike protein and emit an intense fluorescent signal once they’re bound together to the protein. This signal can be easily measured using [… (Read more...)
Face Mask Detects Respiratory Viruses, Alerts User
Scientists at Shanghai Tongji University in China have created a face mask that can alert the wearer to the presence of respiratory viruses in the surrounding environment, including the viruses behind COVID-19 and influenza. The mask includes aptamers, which are short sequences of DNA or RNA that can bind to protein targets. When viral particles [& (Read more...)
Surface Coating Rapidly Kills Pathogens, Lasts Months
A team at the University of Michigan has developed a coating for frequently touched surfaces that can rapidly kill a wide array of pathogens, including MRSA and SARS-CoV-2. The technology incorporates polyurethane that contains crosslinked compounds from essential oils with wide-spectrum anti-microbial action. The researchers fine-tuned the crossli (Read more...)
Point of Care Rapid PCR Test
Columbia University scientists and collaborators at Rover Diagnostics have created a rapid PCR test that can be used at the point of care. Weighing in at two pounds, the portable device can rival the sensitivity and accuracy of traditional lab-based PCR testing equipment, but providing results in as little as 23 minutes. The new device […]
Spray Coating Fights Viruses and Bacteria
Researchers at the University of Sydney in Australia engineered a new spray coating for surfaces that provides long-term protection against bacterial and viral contamination. The material is intended as a long-term alternative to disinfectant sprays and combines hydrophobic properties with antimicrobial nanoparticles to reduce microbial contaminati (Read more...)