Researchers at Cambridge and Bath universities in the UK, along with colleagues at the Ifakara Health Institute in Tanzania, have created two devices, called autohaem, that assist in creating blood smears, a common technique for diagnosing malaria. A blood smear involves manually smudging a drop of blood across a microscope slide to allow observati (Read more...)
Tag: Public Health
Wearable Air Sampler to Assess SARS-CoV-2 Exposure
Researchers at Yale University created a wearable air sampler clip that can be worn on clothing and which can bind aerosols present in the environment. The clip can later be analyzed to determine the level of SARS-CoV-2 exposure while it was worn. The low-cost, battery-free technology could allow people to identify unsafe indoor environments that [ (Read more...)
Quantum Sensor to Detect SARS-CoV-2 More Accurately
Researchers at MIT have designed a quantum sensor to detect SARS-CoV-2. While the device is still theoretical, the researchers have used mathematical simulations to show its potential, and the data and design indicate that it may be faster, more accurate, and less expensive than the current gold-standard technique, PCR. The system is based on nanod (Read more...)
Therapeutic Fusion Protein Inhibits SARS-CoV-2
Researchers at the Technical University of Munich in Germany have developed a new protein therapeutic against SARS-CoV-2. Unlike previously developed antibody therapies and vaccines, the virus is very unlikely to be able to circumvent this latest technology through mutation, as it is based on the viral target site in the body, the ACE2 receptor. Th (Read more...)
Test Detects SARS-CoV-2 in Breath, May Work as COVID Alarm in Enclosed Spaces
Researchers at Brown University have developed a breath test for COVID-19. The breathalyzer, which they have termed the Bubbler, consists of a tube that someone blows into for fifteen seconds. The tube contains a mix of enzymes that reverse transcribe the RNA in viral particles into DNA, which allows for a subsequent benchtop PCR test. […]
High Surface Area Copper for Enhanced Antibacterial Activity
At RMIT University in Australia a team of scientists developed a copper alloy that can kill bacteria on its surface 100 times faster than regular copper. The researchers created the material using copper and manganese atoms, and then removed the manganese after the material was formed, resulting in a comb-like copper structure with massively increa (Read more...)
Flu Virus-Inspired Nanoparticles for mRNA Delivery
Researchers at the University of California San Diego developed a new delivery technique for mRNA. The method involves flu virus-inspired nanoparticles that can escape endosomes, the acidic vesicles that engulf and destroy materials that attempt to enter cells. The nanoparticles contain a protein receptor that allows them to unlock the endosomes an (Read more...)
Quick Test for Antibody Efficacy Against SARS-CoV-2 Variants
At Duke University a team of scientists developed a test that rapidly provides data on how effective antibodies are at neutralizing different COVID-19 variants. The test could be very handy in determining the immunity of a specific patient against various variants, or in deciding on the best monoclonal antibody therapy to use. The researchers have (Read more...)
Chewing Gum Neutralizes SARS-CoV-2
Researchers at the University of Pennsylvania have developed a chewing gum that can bind to SARS-CoV-2 in the saliva, potentially helping to reduce viral transmission. The gum contains the protein ACE2 that can attach to the viral spike protein of SARS-CoV-2. By binding directly to the viral particles, it can prevent them from being transmitted [&h (Read more...)
Imaging Technique Generates 3D Images of Bacteria for Antibiotic Susceptibility Testing
Researchers at the University of Connecticut have developed a highly sensitive imaging sensor that can rapidly and accurately monitor bacterial growth. The technique involves shining laser light through a bacterial sample and taking images at multiple orientations, before reconstructing the diffracted light patterns, to produce a 3D image of the ba (Read more...)
Chip for Investigation of Coronavirus Intestinal Infection
At Harvard’s Wyss Institute researchers used an intestine-on-a-chip to study the way a coronavirus infects the intestines, and the influence of various drugs and immune cells on this process. The intestine chip revealed that remdesivir, a drug that received FDA emergency use authorization for COVID-19 treatment, actually damaged the intestina (Read more...)
Multistep Lateral Flow Devices Perform Advanced Assays
Researchers at Georgia Tech have developed a lateral flow test platform that can perform advanced assays that would otherwise require a laboratory. By controlling the flow of liquid through the lateral flow test, the research team designed it so that it can perform advanced multistep assays that do not require sophisticated lab equipment and signif (Read more...)
Electrochemical Test Measures Antibiotic Resistance
Researchers at Washington State University have developed an electrochemical test that can rapidly identify antibiotic-resistant bacteria in patient samples. The technology can provide a result in less than 90 minutes, and is based on measuring the electrochemical activity of the bacteria after they are exposed to antibiotics. The data reveal the m (Read more...)
Breath Test Developed for COVID-19
Researchers at Ohio State University managed to develop a breath test for COVID-19 that can spot the infection within seconds. The basis for the test is a unique ‘breath print’ of COVID-19 that the researchers have identified, and this includes a specific combination of oxygen, nitric oxide, and ammonia in the breath. At this stage [&he (Read more...)
COVID-19 Vaccine Patch Does Not Require Cold Chain Transport
Researchers at the University of Queensland and Vaxxas, a medtech company, announced the development of a high-density microarray patch (HD-MAP) that can deliver a COVID-19 vaccine through the skin without the need for needles. While such minimally invasive vaccine technology is to be welcomed, the major breakthrough is the temperature stability of (Read more...)
Carbon Nanotube Sensor Detects SARS-CoV-2 Within 5 Minutes
Scientists at MIT announced the development of a rapid COVID-19 test that can detect the virus in a saliva sample in as little as five minutes. The technology does not require antibodies or other expensive reagents typically associated with protein detection, and is instead based on carbon nanotubes. The nano-structures are encased in a web [&helli (Read more...)
DNA Aptamers for Rapid COVID-19 Testing: Interview with Steven Goh, CEO of Achiko and Dr. Michael Edel, Inventor of AptameX
Achiko, a company based in Switzerland, has developed AptameX, a saliva-based rapid COVID-19 test. The technology is based on DNA aptamers that are bound to gold nanoparticles. On binding with a viral protein the gold nanoparticles are released, causing a measurable color change. The test takes approximately 15 minutes in total, with the user spend (Read more...)
Antibiotic Combined with Neutrophil Attractant
Researchers at Monash University in Australia and Harvard University have developed a new treatment for infections caused by antibiotic-resistant bacteria. To achieve this, they attached a chemoattractant to an antibiotic drug molecule, meaning that it attracts neutrophils to the site of an infection and primes them to kill the bacteria. The two-pr (Read more...)
Vaccine Delivery Device Inspired by BBQ Lighter
A team at Georgia Tech tinkered together a battery-free electroporation device to deliver DNA vaccines, which is inspired by BBQ lighters. The details of the workings of the vaccine injector are described in Proceedings of the National Academy of Sciences. The electric ‘spark’ that ignites the gas flowing from a BBQ gas lighter has been (Read more...)
Telemedicine to Monitor At-Risk COVID-19 Patients at Home
Researchers at the Technical University of Munich in Germany have developed a telemedicine system for high-risk COVID-19 patients who are isolating at home. The system consists of an ear sensor that monitors a variety of physiological parameters, including heart rate, respiration, oxygen saturation, and body temperature. The project also involves c (Read more...)