Researchers at the University of Massachusetts Amherst have developed a new method of detecting very small amounts of DNA. The breakthrough could allow clinicians to spot genetic markers of disease at the point-of-care, as the approach does not require conventional laboratory analysis, which is usually time-consuming and costly. In fact, the approa (Read more...)
Tag: Diagnostics
Lateral Flow Test for Gingivitis
Researchers at the University of Cincinnati have developed a lateral flow assay that can detect bacterial toxins from Porphyromonas gingivalis, the causative bacteria for gingivitis. The technology could make it easier and faster to identify early-stage gingivitis, which can lead to periodontitis and eventual tooth loss, as well as contributing to (Read more...)
Lollipop Puts the Fun in Saliva Collection
Researchers at the University of Washington have developed a technique to make saliva collection for diagnostic purposes a little less disgusting and a little more fun and pleasant. Saliva collection often acts as a less invasive alternative than throat swabs in the detection of a variety of pathogens, such as that causing streptococcal soar throat (Read more...)
Virtual Reality Headset Takes EEG Measurements
Researchers at the University of Texas at Austin have developed an electroencephalogram (EEG) sensor that is incorporated into a virtual reality headset. The technology can measure brain activity while someone is undergoing an immersive virtual reality experience. The device may assist in enhancing medical virtual reality interventions, such as tho (Read more...)
EEG Headset Could Spot Early Alzheimer’s Disease
Researchers at the University of Colorado Anschutz Medical Campus have developed a technique that may spot the very early signs of Alzheimer’s disease, years before symptoms arise. The method may alert patients and clinicians to an increased risk of the disease, potentially allowing them to take steps to slow the disease progression. The method inv (Read more...)
Microneedle Skin Patch Measures Cancer Biomarkers
Researchers at the Harvard Wyss Institute have developed a technique that lets clinicians to characterize and monitor melanoma. The system involves using a microneedle patch that can draw deep interstitial fluid into itself through a series of penetrating hyaluronic acid needles. The needles can later be dissolved to release the biomarkers into a t (Read more...)
CRISPR-Equipped Bacteria Detect Tumors
Researchers at the University of California San Diego have created a bacterial sentinel system that can alert clinicians to the presence of tumors. The technology takes advantage of the specificity of the CRISPR system and the tendency of bacteria to uptake fragments of DNA from their environment. Termed “Cellular Assay for Targeted CRISPR-discrimi (Read more...)
Device for Rapid COVID-19 Breath Testing
Researchers at Washington University School of Medicine have developed a COVID-19 breathalyzer test. The technology requires someone to breathe into it just once or twice, and it can then provide an indication if the person is infected with SARS-CoV-2 in as little as one minute. The device could be very useful fo screening large numbers […]
Ultrasound-Equipped Bra Monitors for Breast Cancer
Researchers at MIT have developed a wearable ultrasound system that is intended to allow women at high risk of breast cancer to perform an ultrasound scan on themselves at home, and may also let patients with early-stage malignancy or suspicious lesions to monitor how they are progressing. The technology can help patients to avoid having […]
Gravity-Driven Microfluidics for Low-Cost Diagnostics
Researchers at Duke University have developed a gravity-powered microfluidic device that is intended for use as a diagnostic technology in low-resource areas. Microfluidics have enormous potential for point-of-care diagnostics, but the inclusion of tiny pumps and other sophisticated electronic components dramatically increases the complexity and co (Read more...)
Photonic Radar Monitors Breathing from a Distance
Engineers at the University of Sydney have developed a photonic radar that allows them to monitor breathing rates without the need to attach equipment to a patient’s skin. Wired or more invasive systems may not be suitable for everyone – for instance, burn patients with damaged skin or infants with a tiny body surface area […]
Wound Sensor Patch Indicates Healing Status
Researchers at the National University of Singapore have created a wound sensor patch that measures various wound biomarkers that can indicate would healing. Chronic wounds are an ongoing problem for many patients, and developing new ways to monitor and treat these painful lesions would be very useful. This battery-free wound patch contains five co (Read more...)
CRISPR-Cas13 Test Inexpensively and Rapidly Reveals HIV Viral Load
Scientists at Penn State have developed an assay that lets them to directly measure HIV viral load in a drop of blood. The technology is also faster and less expensive than current approaches. At present, RT-PCR is typically used to assess HIV levels in a patient’s blood, requiring genetic material to be amplified before it […]
App Converts Smartphone to Clinical Thermometer
Researchers at the University of Washington have developed an app that converts common smartphones into clinical thermometers. Spotting the signs of fever early could make a difference in providing early treatment or beginning a period of isolation to reduce the chance of disease transmission. This is particularly important for viral diseases, such (Read more...)
Wearable Takes Blood-Free Stress Hormone Samples
Researchers at the University of Birmingham in the UK have developed a wearable that can assist in keeping track of stress hormone levels in the body over time. Disregulated stress hormones can play a role in various disease states, from heart disease to depression. However, until now, researchers had to perform blood draws to measure […]
Microfluidic Chip Aids Tuberculosis Diagnosis
Researchers at the University of London have collaborated with QuantuMDx, a medtech company based in the UK, to develop a microfluidic diagnostic device for tuberculosis. The CAPTURE-XT chip is designed to concentrate and purify Mycobacterium tuberculosis from suspected tuberculosis patients, particularly in areas that lack access to routine diagno (Read more...)
CRISPR Combined with Glowing Proteins for Viral Detection
Researchers at Eindhoven University of Technology in the Netherlands have developed a sensitive diagnostic test for viral pathogens that is suitable for use in low-resource regions. The test is based on CRISPR proteins that can detect viral genetic material but also incorporates luciferase proteins, which are bioluminescent proteins that are natura (Read more...)
Imagene Profiles Cancer Biomarkers in Real Time
Cancer therapies have proliferated over the past few decades, improving outcomes for many patients. But this variety requires accurate diagnostics and appropriate decision making to choose the optimal course of therapy. The current gold standard of identifying which cancer mutation is present is new generation sequencing (NGS), which provides a com (Read more...)
Smartphone Photos to Detect Anemia
Researchers at University College London and at the University of Ghana have developed a smartphone-based system that can detect anemia through simple photos taken using the phone’s camera. The technology is intended for use in low- and middle-income countries where access to routine medical diagnostics may be unreliable. The process involves (Read more...)
Bacteria Create Protein Nanowires for Biosensing
Scientists at the University of Massachusetts Amherst have developed a biosensor that is based on protein nanowires that are created by bacteria. The protein nanowires are highly sensitive to ammonia, in this case, which is present in the breath of patients with kidney disease, but it is likely possible to create nanowires for a huge […]