Tag: Cardiac Surgery

Shear-Thinning Biomaterial for Embolic Applications: Interview with Upma Sharma, President and CEO of Arsenal Medical

Arsenal Medical, a medtech company based in Massachusetts, has developed Neocast, an embolic biomaterial designed for catheter-mediated embolization procedures. Conventional materials for embolization can have several limitations, including a lack of radiopacity, catheter clogging, catheter entrapment at the delivery site, solvent-mediated pain at (Read more...)

3D Printed Heart Muscle Beats

Researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences have developed a technique that allows them to 3D print a heart ventricle, that can then go on to beat rhythmically. The technology could allow researchers to create heart models to test new cardiac drugs and may even pave the way for […]

Wireless Patch Monitors, Paces Heart and then Biodegrades

Researchers at Northwestern University have developed a cardiac monitoring device that is intended for use in patients who have suffered a cardiac event. The soft and flexible patch can be affixed to the outside of the heart during a routine procedure, but does not require a second procedure to remove the device later, as it […]

Heart Valves Made in Minutes

Researchers at Harvard University have developed a technique that lets them create biomaterial heart valves in a matter of minutes. The approach, called ‘Focused Rotary Jet Spinning’, has been described by the researchers as ‘a cotton-candy machine with a hair dryer behind it.’ Essentially, the technique involves using jets (Read more...)

Conductive Polymer Electrode is Metal-Free

Researchers at MIT have developed a metal-free electrode using conductive polymers. The electrode is flexible and strong enough for long-term implantation in the body. The device is intended as an advanced replacement for rigid metal electrodes that can cause tissue damage and scarring over the long term, leading to device failure. The new technolo (Read more...)

Scientists Grow Electrodes Inside The Body

Researchers at Linköping University in Sweden have developed a method whereby the body can ‘grow its own’ electrodes. The minimally invasive technique involves injecting a hydrogel that is laden with enzymes into target tissues. The enzymes interact with molecules that are present in the tissue to change the structure of the gel an (Read more...)

Electrospun Construct Mimics Elasticity of Blood Vessels

Researchers at the University of Sydney in Australia have developed an electrospun blood vessel replacement. The material contains tropoelastin, a natural precursor for elastin, a key component of blood vessel walls. Elastin is present in concentric circles in natural blood vessels and provides the elastic properties which allow them to distend sli (Read more...)

Battery-Free Light-Powered Pacemaker Now a Reality

Researchers at the University of Arizona have developed a battery-free light-powered pacemaker that uses optogenetic stimulation of cardiomyocytes to achieve heart pacing. With conventional pacemakers, the leads of the device are anchored into the wall of the heart, using invasive hooks or screws. Small electrical shocks are then sent through the e (Read more...)

Soft Robot Grows Like a Plant to Travel Through Tight Spaces

At the University of Minnesota, researchers have developed a soft robotic system that can ‘grow’ like a plant. The mechanism allows it to travel through difficult-to-access areas, such as the tortuous gastrointestinal tract or vasculature. The system works by extruding a liquid through an opening in the device, and at the same time a ph (Read more...)

Silicone Heart Models Heart Failure

Scientists at the Royal College of Surgeons in Ireland and partners at the National College of Art and Design in Dublin have developed a silicone heart model that is intended to model heart failure with preserved ejection fraction. The device, which represents a ‘mock circulatory loop’, includes a simulated version of the left atrium an (Read more...)

Biosynthetic Trilayered Ventricle Pumps Blood

Biomedical engineers at the University of Toronto have developed a method to create a small-scale biosynthetic left ventricle that can pump blood within a bioreactor. While the construct is too small to act as replacement for a human heart, it could lead to full-sized biosynthetic organ transplants. In fact, the man-made ventricle already showed a (Read more...)

Artificial Ventricle Mimics Helical Muscle Fibers

Researchers at Harvard developed a technique that lets them recreate the helical arrangement of cardiac muscle fibers within the heart ventricles in a bioengineered construct. The breakthrough could pave the way for artificial bioengineered hearts. The researchers used a technique called Focused Rotary Jet Spinning (FRJS) that allows them to deposi (Read more...)

TORdx LUNG Test for Donor Lung Assessment: Interview with Eric Brouwer, Chief Scientific Officer at SQI Diagnostics

SQI Diagnostics, a medtech company based in Canada, is developing the TORdx LUNG Test. The technology is intended to assist clinicians in assessing donor lungs in their suitability for transplantation. At present, clinicians typically assess donor lungs using qualitative variables, such as donor health and lung size. One of the most important facto (Read more...)

Improving Transplant Survival with Organ Preservation Tech: Interview with Dr. Anderson, CEO of Paragonix

Paragonix Technologies, a medtech company based in Massachusetts, created the SherpaPak, an FDA organ transportation device that is intended to keep donor organs safe and viable on their journey to a transplant recipient. As the viability of a donor organ can mean life or death for the receiving patient, it makes sense to take exceptional [… (Read more...)

Magnetic Steering System for Guidewires

Percutaneous coronary intervention is an incredibly useful technique to minimally invasively investigate and treat cardiac issues, such as blockages in the coronary arteries, but it requires a significant amount of skill to perform safely and effectively. Manipulating a guidewire through the tortuous vasculature is not for the faint hearted, with t (Read more...)

Lipid Nanodiscs Unlock the Potential of Cytokine Treatment

Researchers at the University of Texas at Austin created a nanocarrier for stem cell factor, a regenerative cytokine. The nanotechnological approach renders the treatment much safer, as previous attempts to use stem cell factor as a pro-angiogenic treatment have been hampered by severe allergic reactions in some recipients. This latest technology h (Read more...)

Melt Electrowriting to Make Fibrous Heart Valve Scaffolds

Researchers at the Technical University of Munich in Germany have developed a technique to create heart valve scaffolds that can mimic the variable mechanical properties of the real thing. The researchers used a method called melt electrowriting to create complex and variable patterns in the fibrous scaffolds, allowing them to mimic the structure a (Read more...)