Researchers at the University of Sydney in Australia have developed an electrospun blood vessel replacement. The material contains tropoelastin, a natural precursor for elastin, a key component of blood vessel walls. Elastin is present in concentric circles in natural blood vessels and provides the elastic properties which allow them to distend sli (Read more...)
Tag: Cardiac Surgery
Battery-Free Light-Powered Pacemaker Now a Reality
Researchers at the University of Arizona have developed a battery-free light-powered pacemaker that uses optogenetic stimulation of cardiomyocytes to achieve heart pacing. With conventional pacemakers, the leads of the device are anchored into the wall of the heart, using invasive hooks or screws. Small electrical shocks are then sent through the e (Read more...)
FDA-Approved At-Home Spirometer: Interview with Charvi Shetty, Co-Founder and CEO at Aluna
The COVID-19 pandemic has put lung health firmly in our minds. For those with chronic lung diseases, such as asthma and COPD, an important way to keep track of lung health is to use a spirometer to measure how well air can move in and out of the lungs during forced breathing. However, patients would […]
Soft Robot Grows Like a Plant to Travel Through Tight Spaces
At the University of Minnesota, researchers have developed a soft robotic system that can ‘grow’ like a plant. The mechanism allows it to travel through difficult-to-access areas, such as the tortuous gastrointestinal tract or vasculature. The system works by extruding a liquid through an opening in the device, and at the same time a ph (Read more...)
Silicone Heart Models Heart Failure
Scientists at the Royal College of Surgeons in Ireland and partners at the National College of Art and Design in Dublin have developed a silicone heart model that is intended to model heart failure with preserved ejection fraction. The device, which represents a ‘mock circulatory loop’, includes a simulated version of the left atrium an (Read more...)
Biosynthetic Trilayered Ventricle Pumps Blood
Biomedical engineers at the University of Toronto have developed a method to create a small-scale biosynthetic left ventricle that can pump blood within a bioreactor. While the construct is too small to act as replacement for a human heart, it could lead to full-sized biosynthetic organ transplants. In fact, the man-made ventricle already showed a (Read more...)
Artificial Ventricle Mimics Helical Muscle Fibers
Researchers at Harvard developed a technique that lets them recreate the helical arrangement of cardiac muscle fibers within the heart ventricles in a bioengineered construct. The breakthrough could pave the way for artificial bioengineered hearts. The researchers used a technique called Focused Rotary Jet Spinning (FRJS) that allows them to deposi (Read more...)
TORdx LUNG Test for Donor Lung Assessment: Interview with Eric Brouwer, Chief Scientific Officer at SQI Diagnostics
SQI Diagnostics, a medtech company based in Canada, is developing the TORdx LUNG Test. The technology is intended to assist clinicians in assessing donor lungs in their suitability for transplantation. At present, clinicians typically assess donor lungs using qualitative variables, such as donor health and lung size. One of the most important facto (Read more...)
Improving Transplant Survival with Organ Preservation Tech: Interview with Dr. Anderson, CEO of Paragonix
Paragonix Technologies, a medtech company based in Massachusetts, created the SherpaPak, an FDA organ transportation device that is intended to keep donor organs safe and viable on their journey to a transplant recipient. As the viability of a donor organ can mean life or death for the receiving patient, it makes sense to take exceptional [… (Read more...)
Magnetic Steering System for Guidewires
Percutaneous coronary intervention is an incredibly useful technique to minimally invasively investigate and treat cardiac issues, such as blockages in the coronary arteries, but it requires a significant amount of skill to perform safely and effectively. Manipulating a guidewire through the tortuous vasculature is not for the faint hearted, with t (Read more...)
Lipid Nanodiscs Unlock the Potential of Cytokine Treatment
Researchers at the University of Texas at Austin created a nanocarrier for stem cell factor, a regenerative cytokine. The nanotechnological approach renders the treatment much safer, as previous attempts to use stem cell factor as a pro-angiogenic treatment have been hampered by severe allergic reactions in some recipients. This latest technology h (Read more...)
Melt Electrowriting to Make Fibrous Heart Valve Scaffolds
Researchers at the Technical University of Munich in Germany have developed a technique to create heart valve scaffolds that can mimic the variable mechanical properties of the real thing. The researchers used a method called melt electrowriting to create complex and variable patterns in the fibrous scaffolds, allowing them to mimic the structure a (Read more...)
Dissolving Pacemaker Communicates with Patient and Wearable Tech
Researchers at Northwestern University have created a cardiac pacemaker that dissolves away, negating the need for a procedure to remove it. The pacemaker was originally announced in 2021, but in this follow-up study, the researchers have enhanced its functionality. The device can now communicate with a network of wireless sensors that are worn on (Read more...)
Smart Stent Monitors Hemodynamics
Researchers at the Georgia Institute of Technology have developed a smart stent that can monitor hemodynamic parameters. The wireless and battery-free device can transmit the data to the outside of the body, and is powered through a wireless energy transfer system that uses magnetic fields, similar to wireless chargers that are available for many s (Read more...)
Heart Chamber on a Chip
Researchers at Boston University engineered a heart chamber on a chip that can beat by itself. The technology relies on cardiomyocytes generated from induced pluripotent stem cells and small acrylic valves that allow the fluid pumped by the chamber to come and go. The chamber is supported by a thin acrylic scaffold that aims to […]
Wireless Data Transfer for Implanted Devices Using Ionic Communication
Researchers at the Columbia University School of Engineering and Applied Science have developed a new method for implanted devices to communicate with the outside world that exploits the ions that are naturally present in our tissues. Ion-rich tissues store potential energy, and in this paradigm an implanted device would alter this stored energy wi (Read more...)
vMap Mapping Technology for Cardiac Arrhythmias: Interview with Mike Monko, CEO of Vektor Medical
Vektor Medical, a medtech company based in San Diego, created the vMap system, a mapping solution for cardiac arrhythmias. The system is the first to identify arrhythmia sources anywhere in the heart, including the septal wall, outflow tracts, and all four chambers. The company reports that the technology takes less than three minutes to provide [& (Read more...)
vMap Mapping Technology for Cardiac Arrhythmias: Interview with Mike Monko, CEO of Vektor Medical
Vektor Medical, a medtech company based in San Diego, created the vMap system, a mapping solution for cardiac arrhythmias. The system is the first to identify arrhythmia sources anywhere in the heart, including the septal wall, outflow tracts, and all four chambers. The company reports that the technology takes less than three minutes to provide [& (Read more...)
Blood Clotting Test on a Smartphone
Researchers at the University of Washington have developed smartphone-based technology that can allow someone to perform a blood clotting test at home. The technology is low-cost and easy to use. The test involves placing a drop of blood into a plastic attachment that can be viewed by a smartphone camera. The smartphone then vibrates the […]
(Read more...)Lab-Designed “Fish” Could Pave the Way for Artificial Hearts
Researchers at Harvard University have created a fish-like construct from human stem cell-derived cardiac muscle. The structure can beat and swim autonomously, and is inspired by zebrafish. So far, the researchers have shown that the fish can survive and swim for over 100 days, and they hope these new structures could provide insights into cardiac (Read more...)