Physico-chemical stability of high-concentration ready-to-use ophthalmic solutions: literature review

Source: Annales Pharmaceutiques Francaises
Area: Evidence > Medicines Management > References
Introduction: Ophtalmic infections and inflammations are often encountered during hospitalisation.  They require the preparation of 'fortified' ophthalmic solutions, i.e. pharmaceutical ophthalmic solutions which have a higher concentration of the active substance.  Data on physicochemical stabilities are modified and it is therefore essential to collect the results of the various publications on this subject. Method: In 2006, an initial literature review was undertaken to identify the molecules mostly used in the preparation of 'fortified' ophthalmic solutions in hospital.  A second review of the (Read more...)