An antibody targeting the interleukin-6 receptor may help reduce bulging of the eyes and inflammation in patients with thyroid eye disease, early phase 3 data show. Medscape Medical News
Tag: Clinical Summary
Once-Nightly Eye Drop Aids Dim-Light Vision
In patients who face difficulty seeing in low light, a once-nightly eye drop significantly improves night vision and reduces glare, halos, and starbursts, a phase 3 trial shows. Medscape Medical News
Modified Vitamin A May Slow Rare Vision Disease
A deuterium-enriched vitamin A pill slows the growth of retina-damaging lesions in Stargardt disease by more than 20%, according to a recent clinical trial. Medscape Medical News
Letter-Matching Test Favored for Vision Screening in Kids
A vision test that requires young children to match letters may screen better for reduced vision than a test requiring them to indicate the orientation of a letter. Medscape Medical News
CKM Syndrome Tied to Major Blinding Eye Diseases
Cardiovascular-kidney-metabolic syndrome is associated with an increased risk of developing major blinding eye diseases in a large UK cohort, with stage 3 showing the highest rates. Medscape Medical News
Common Lipid-Lowering Drug May Slow Diabetic Eye Damage
A common lipid-lowering drug is tied to markedly lower odds of vision-threatening retinopathy, cataracts, and macular edema in patients with mild or moderate nonproliferative diabetic retinopathy. Medscape Medical News
Aspherical Lenslets Slow Myopia Progression in Kids
A novel spectacle lens design featuring aspherical lenslets reduced myopia progression in children by more than 70% compared with standard single-vision lenses over 24 months. Medscape Medical News
Retinal Thinning Predicts Cognitive Decline in MS
Thinning of specific retinal layers predicts cognitive worsening in patients with multiple sclerosis, even without disease relapses — suggesting the eye may reveal hidden neurodegeneration. Medscape Medical News
Pachychoroid Disease Progression Remains Low
Most eyes with pachychoroid features maintained their subtype over 2 years, with progression to pachychoroid neovasculopathy developing in only a small fraction of eyes. Medscape Medical News
Can Dexamethasone Drops Prevent Retinal Disease in Preemies?
Dexamethasone eye drops administered in premature infants with early-stage retinal disease appear to reduce the odds of progression to treatment-requiring disease. Medscape Medical News
Massage Matches Clinic Probing for Infant Tear Duct Blockage
Gently massaging the tear sacs of infants with blocked tear ducts may be as effective as clinic-based probing for clearing tearing and discharge, a noninferiority trial finds. Medscape Medical News
Duration and Age Tied to Different Complication Risks in T1D
In patients with childhood onset T1D, a longer diabetes duration is mainly linked to a higher risk for retinopathy, and older age more strongly predicts albuminuria after over 30 years of follow up. Medscape News UK
Urinary Drug Tadalafil Linked to Glaucoma Risk
Men taking tadalafil for lower urinary tract symptoms face a 22% higher risk of developing glaucoma than those who do not take the drug, a new study finds. Medscape Medical News
Uveitis May Flag Possibility of Axial Spondyloarthritis
Many patients with nongranulomatous acute anterior uveitis may be diagnosed with previously unrecognized axial spondyloarthritis after rheumatologic evaluation. Medscape Medical News
1 in 8 Hockey Eye Injury Diagnoses Vision-Threatening
US emergency rooms saw an estimated 6466 hockey-related ocular injury cases over a 20-year span, with a notable share being vision-threatening, a recent study shows. Medscape Medical News
AI Detects AMD in Primary Care With High Accuracy
A new AI tool may screen for age-related macular degeneration using simple eye photos, with no need for dilation. Medscape Medical News
Chronic Pain Conditions Linked to Risk for Dry Eye Disease
Chronic pain is associated with a significantly increased risk for developing dry eye disease over 3 years, a study finds. Medscape Medical News
Study Links Uveitis to Higher Risk for Psychiatric Illness
Noninfectious uveitis is linked to higher rates of psychiatric comorbidities, with Black patients most affected, a new study finds. Medscape Medical News
Zanubrutinib May Benefit Patients With IgG4-Related Disease
Zanubrutinib monotherapy may help shrink inflamed glands, ease symptoms, and is generally well tolerated in patients with immunoglobulin G4-related head and neck disease, a phase 2 study shows. Medscape Medical News
Faricimab May Aid Hard-to-Treat Macular Degeneration Cases
Faricimab may stabilize vision, reduce retinal fluid and thickness, and cut treatment burden in difficult-to-treat cases of wet age-related macular degeneration. Medscape Medical News