Systematic Review: Comparative effectiveness of treatments for open-angle glaucoma

Source: Ann Intern Med
Area: News
The Annals of Internal Medicine has featured a systematic review comparing the effectiveness of medical, laser, and surgical treatments in adults with open-angle glaucoma with regard to decreasing intraocular pressure and preventing optic nerve damage, vision loss, and visual impairment.   Data from a total of 23 randomised trials, observational studies and systematic reviews were included in this analysis.   The researchers reported that high-level evidence suggests that medical, laser, and surgical treatments decrease intraocular pressure and that medical treatment and trabeculectomy reduce the risk for optic nerve damage and visual field loss compared with no treatment. In terms of medical interventions, they conclude that topical glaucoma medications decrease intraocular pressure (IOP), with prostaglandins being superior to other monotherapies.   In conclusion, the researchers report that medical and surgical treatments for open-angle glaucoma ...