Publication date: January 2013
Source:Progress in Retinal and Eye Research, Volume 32
Author(s): Thomas F. Freddo
This review traces the evolution of the concept of the blood–aqueous barrier (BAB) during the past 20 years. The Classical model simply stipulated that the tight junctions of the iris vasculature and ciliary epithelium (Read more...)
Month: April 2013
Herpes keratitis
Publication date: January 2013Source:Progress in Retinal and Eye Research, Volume 32 Author(s): A.M. Rowe , A.J. St. Leger , S. Jeon , D.K. Dhaliwal , J.E. Knickelbein , R.L. Hendricks Herpes simplex virus-1 (HSV-1) infects the m…
New insights into retinoid metabolism and cycling within the retina
Publication date: January 2013Source:Progress in Retinal and Eye Research, Volume 32 Author(s): Peter H. Tang , Masahiro Kono , Yiannis Koutalos , Zsolt Ablonczy , Rosalie K. Crouch The retinoid cycle is a series of biochemical re…
Role of the retinal vascular endothelial cell in ocular disease
Publication date: January 2013Source:Progress in Retinal and Eye Research, Volume 32 Author(s): Arpita S. Bharadwaj , Binoy Appukuttan , Phillip A. Wilmarth , Yuzhen Pan , Andrew J. Stempel , Timothy J. Chipps , Eric E. Benedett…
Novel anti(lymph)angiogenic treatment strategies for corneal and ocular surface diseases
Publication date: May 2013Source:Progress in Retinal and Eye Research, Volume 34 Author(s): Felix Bock , Kazuichi Maruyama , Birgit Regenfuss , Deniz Hos , Philipp Steven , Ludwig M. Heindl , Claus Cursiefen The cornea is one of…
Optical plasticity in fish lenses
Publication date: May 2013
Source:Progress in Retinal and Eye Research, Volume 34
Author(s): Ronald H.H. Kröger
In a typical fish eye, the crystalline lens is the only refractive element. It is spherical in shape and has high refractive power. Most fish species have elaborate color vision and spectral sensitivity (Read more...)
Macular telangiectasia type 2
Publication date: May 2013
Source:Progress in Retinal and Eye Research, Volume 34
Author(s): Peter Charbel Issa , Mark C. Gillies , Emily Y. Chew , Alan C. Bird , Tjebo F.C. Heeren , Tunde Peto , Frank G. Holz , Hendrik P.N. Scholl
Macular telangiectasia type 2 is a (Read more...)
Neuromodulatory role of melatonin in retinal information processing
Publication date: January 2013Source:Progress in Retinal and Eye Research, Volume 32 Author(s): Hai Huang , Zhongfeng Wang , Shi-Jun Weng , Xing-Huai Sun , Xiong-Li Yang The neurohormone melatonin is implicated in a variety of phy…
Gap junctional coupling in the vertebrate retina: Variations on one theme?
Publication date: May 2013
Source:Progress in Retinal and Eye Research, Volume 34
Author(s): Béla Völgyi , Tamás Kovács-Öller , Tamás Atlasz , Márta Wilhelm , Róbert Gábriel
Gap junctions connect cells in the bodies of all multicellular organisms, forming either homologous or heterologous (i.e. established between identical or different (Read more...)
Editorial board/title page
Publication date: November 2012Source:Progress in Retinal and Eye Research, Volume 31, Issue 6
Outlook For Minority, Uninsured Pediatric Retinoblastoma Patients Worsened By Delays In Diagnosis
When the eye cancer retinoblastoma is diagnosed in racial and ethnic minority children whose families don’t have private health insurance, it often takes a more invasive, potentially life-threatening course than in other children, probably because of d…
Two-Part Treatment Improves Outlook for Keratoconus
Surgeons in Mexico think they might have found a way to stabilize the corneas of patients with keratoconus, enabling them to see normally, without refractive correction. Medscape Medical News
Treatment for Concomitant Cataract and Glaucoma
Do phacotrabeculectomy and phacocanaloplasty both help to lower IOP in patients with concomitant cataract and glaucoma? This new study compares the 2 surgical procedures. BMC Ophthalmology
American Society of Cataract and Refractive Surgery (ASCRS) 2013 Symposium
Read clinically focused news coverage of key developments from ASCRS 2013. Medscape Ophthalmology
Fixed-dose combination of drugs effectively lowers IOP
A fixed-dose combination of brinzolamide and brimonidine is more effective than either drug given alone for lowering intraocular pressure in patients with open-angle glaucoma or ocular hypertension, results of a phase III trial indicate.
Outcomes of Corneal Transplantation for Irreversible Corneal Decompensation Secondary to Corneal Endotheliitis in Asian Eyes – Corrected Proof
Purpose: To describe outcomes of corneal transplantation for irreversible corneal decompensation from corneal endotheliitis in Asian eyes.Design: Retrospective, observational case series.Methods: We reviewed consecutive patients with corneal endothelii…
Pediatric Ptosis as a Sign of Treatable Autonomic Dysfunction – Corrected Proof
Purpose: To report the ophthalmic findings in young patients with dopamine β-hydroxylase deficiency and to assess them in the context of other reports in an attempt to discern if ophthalmic criteria may assist in early detection of this debilitating, …
Efficacy of Inverted Internal Limiting Membrane Flap Technique for the Treatment of Macular Hole in High Myopia – Corrected Proof
Purpose: To determine the effect of pars plana vitrectomy (PPV) with inverted internal limiting membrane (ILM) flap technique for macular hole with or without retinal detachment in highly myopic eyes.Design: Retrospective, interventional case series.Me…
Role of Oral Corticosteroids in Orbital Cellulitis – Corrected Proof
Purpose: To evaluate the role of oral corticosteroids as an anti-inflammatory adjunct in the treatment of orbital cellulitis.Design: Prospective, comparative, single-masked, interventional clinical study.Methods: setting: Tertiary eye care center (All India Institute of Medical Sciences). study population: Patients with acute onset (within 14 days) of orbital cellulitis with or without abscess. intervention: Patients were randomized into 2 groups in the ratio of 1:2. Both groups received initial intravenous antibiotics. In Group 2, oral steroids were added after an initial response to intravenous antibiotics. main outcome measures: Resolution of signs and symptoms, duration of intravenous antibiotics, length of hospital stay, and sequelae (Read more...)
Deep Anterior Lamellar Keratoplasty versus Penetrating Keratoplasty for Macular Corneal Dystrophy: A Randomized Trial – Corrected Proof
Purpose: To compare outcomes of big-bubble deep anterior lamellar keratoplasty (DALK) and penetrating keratoplasty (PK) for macular corneal dystrophy.Design: Prospective, randomized, interventional case series.Methods: setting: Single hospital. patients: Eighty-two eyes of 54 patients requiring keratoplasty for the treatment of macular corneal dystrophy without endothelial involvement were included. main outcome measures: Operative complications, uncorrected visual acuity, best-corrected visual acuity, contrast sensitivity function, higher-order aberrations, and endothelial cell density were evaluated.Results: The DALK and PK group consisted of 35 and 41 eyes, respectively. Best-corrected visual acuity after surgery was 20/40 or better 68.5% and 70.7% of the eyes in the DALK and (Read more...)