Source: N Engl J Med
Area: News
Lichen planus is a mucocutaneous inflammatory disease of unknown origin. The skin and oral mucosa are the most frequently involved areas. Other mucous membranes (including the genitalia, oesophagus, and conjunctiva) and skin appendages (e.g. scalp hair and nails) can also be affected. Therapy depends on the location and severity of the lesions. Since data from RCTs are limited, treatment choices are guided largely by clinical experience. Commonly used therapies include topical glucocorticoids, systemic glucocorticoids, topical retinoids, and phototherapy.
This review in the New England Journal of Medicine begins with a case vignette, a discussion of the evidence supporting various strategies, a review of formal guidelines, when they exist, and ends with the authors' clinical recommendations of the management of the case presented.
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