Should a patient with signs of retinal toxicity be taken off HCQ completely, or are a reduced dose and additional screening more appropriate?

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Hydroxychloroquine is a drug used by many rheumatologists and dermatologists as a first-line agent to treat conditions from arthritis to lupus to alopecia. HCQ is an effective agent, but there is always a small risk for irreversible retinal toxicity.
HCQ toxicity primarily affects the macula, and patients taking more than 5 mg/kg/day (based on real body weight) are at the highest risk for having damage. The most common symptoms of toxicity are color vision changes and paracentral scotomas. We have (Read more...)

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