Author Archive for Healio ophthalmology

PUBLICATION EXCLUSIVE: Descemet’s membrane endothelial keratoplasty slowly on the rise

Lamellar techniques have almost entirely replaced penetrating keratoplasty. They have undergone progressive refinements and have more recently evolved toward minimizing the presence of allogenic tissue in the eye to prevent rejection and graft failure.“Overall, if we can work toward smaller grafts or no graft at all, this is going to benefit the patient in many ways. On the other hand, if we can multiply the number of grafts we can obtain from the same donor, we can reduce the costs and the problem of tissue shortage in some areas of (Read more...)

Alimera allowed to reduce size of Iluvien study in UK

The United Kingdom’s Medicines and Healthcare Products Regulatory Agency has given final approval to reduce the size of Alimera Sciences’ post-marketing study of Iluvien, according to a company press release.The study, originally intended to follow 800 patients over 5 years, has shown consistent positive safety data, leading the company to seek a smaller sample size, the release said. There are currently 550 patients enrolled.

The state of dry eye care, part 2

As we head into the summer months, I thought it would be helpful to take the pulse of our dry eye world and report on the state of the state, if you will. In part 1 I reviewed how we are diagnosing dry eye in our clinics — and learned that the news cycle does not respect the editorial/creative process when RPS sold InflammaDry while my piece was in turnaround. Let us now examine the state of dry eye disease treatment.As a group, doctors who treat DED have become much (Read more...)

Sustained-release therapies remove patient factor from glaucoma treatment

Sustained delivery devices that take glaucoma therapy out of patients’ hands may be the answer to the many issues related to adherence, with significant benefits for patients and physicians.Not yet available on the U.S. market, these technologies fall under the broad category of guided administration of pharmaceuticals (GAP), ranging from injectable sustained-release formulations, to drug-eluting rings and contact lenses, to punctal plug reservoirs. Many are in the pipeline, undergoing phase 2 or nearing phase 3 trials.

Man presents with blurry vision, flashes, floaters and redness

A 53-year-old Caucasian man presented with a 3-week history of worsening blurry vision of the left eye associated with flashes, floaters and redness. He also complained of a recent fever that lasted 2 weeks and resolved on its own. He noted that he recently had a “sore” in his mouth that also resolved.The patient had a medical history of hypertension and hyperlipidemia. His ocular history was significant only for refractive error. He denied any tobacco use and reported social alcohol use. He had no pets at home. He worked as (Read more...)

Descemet’s membrane endothelial keratoplasty slowly on the rise

Lamellar techniques have almost entirely replaced penetrating keratoplasty. They have undergone progressive refinements and have more recently evolved toward minimizing the presence of allogenic tissue in the eye to prevent rejection and graft failure.“Overall, if we can work toward smaller grafts or no graft at all, this is going to benefit the patient in many ways. On the other hand, if we can multiply the number of grafts we can obtain from the same donor, we can reduce the costs and the problem of tissue shortage in some areas of (Read more...)