In October 2025, the FDA issued a complete response letter to Sydnexis regarding SYD-101, an investigational formulation of low-dose atropine 0.01%. Despite achieving its primary phase 3 efficacy endpoint, the eye drop was not approved.More recently, t…
Author: Healio ophthalmology
Panel examines myopia control spectacle lenses, pediatric imaging
The myopia epidemic continues to pose a significant international challenge, but the eye care community has made strides in reducing its progression in pediatric patients.In September 2025, the FDA granted market authorization to Essilor Stellest spect…
Governance key to balancing AI augmentation, risk for deskilling
An aircraft’s autopilot can guide every aspect of a flight, from takeoff to landing. But it is expected, and reassuring to know, that a pilot has the skills to intervene and assume manual control at any time, especially during an emergency.There is a s…
Q&A: How women physicians can find joy in personal finance
Brittne Halford, MD, MPH, paid off $138,000 in medical school debt in 2 years and 9 months without feeling (terribly) deprived of the good things in life.“I am from a family that’s rich in culture and community and support, but not as far as passing do…
Case study: Claw-like part of insect found in lid abscess
The orbital septum is a thin fibrous membrane that separates the preseptal soft tissue from the postseptal orbital contents.The septum begins at the orbital rim, where it attaches directly to the periosteum at a thickened ridge called the arcus margina…
Study shows long-term efficacy, safety of aflibercept 0.4 mg in ROP
VIENNA — Aflibercept 0.4 mg intravitreal injection in preterm and low birthweight infants with acute-phase retinopathy of prematurity was effective and well tolerated over 5 years of follow-up in a study presented at the Euretina congress.Based on the …
FDA clears investigational NDA for SZN-8141
Editor’s note: This is a developing story. Please check back soon for updates.The FDA cleared an investigational new drug application for SZN-8141, a Wnt agonist and VEGF antagonist antibody designed to treat diabetic macular edema, according to a pres…
Recruit for excellence ‘first, foremost’ but community care matters
Diversity, equity and inclusion efforts in medical practice are not just about reaching underserved communities but should also influence who is recruited to care for them.According to Andy Tau, MD, FACG, FASGE, chair of recruiting at Austin Gastroente…
Neurotrophic keratitis: Management strategies across the spectrum
Welcome to another edition of CEDARS/ASPENS Debates. CEDARS/ASPENS is a society of cornea, cataract and refractive surgery specialists, here to discuss some of the latest hot topics in ophthalmology.This month we are discussing the management of severe…
New classification may standardize surgical site management
Researchers developed and validated a new classification system that may standardize reporting of all relevant grades of clinical presentation and management of surgical site outcomes, according to published results.To develop a classification system f…
SpyGlass Pharma acquires Advanced Vision Science
Editor’s note: This is a developing story. Please check back soon for updates.SpyGlass Pharma announced the acquisition of Advanced Vision Science in an effort to boost its IOL manufacturing capacity, according to a press release.SpyGlass acquired all …
Q&A: How to build a nontraditional career as a physician
Growing up, Naomi Lawrence-Reid, MD, always knew she wanted to be a doctor.Her career as a physician looks different from what she pictured as a medical student, but she said she wouldn’t have it any other way.After medical school, Lawrence-Reid comple…
ECO-CAIRS represents evolution in use of allogenic ring segments
The management of keratoconus has evolved substantially over 3 decades.While corneal transplantation was historically the only surgical option for advanced disease, intracorneal ring segments (ICRS), first implanted by Walton Nosé in 1993 and later pop…
HHS launches initiatives to make clinical trials faster
HHS launched a multi-component effort intended to improve the speed and efficiency with which clinical trials are conducted.The series of initiatives is designed to eliminate duplication, ensure more efficient enrollment and provide patients with earli…
4D-150 shows safety, vision gains in diabetic macular edema
In part one of the SPECTRA clinical trial, 4D-150, an intravitreal gene therapy, demonstrated positive safety outcomes as well as vision gains and central subfield thickness reduction in patients with diabetic macular edema.“For DME patients, the curre…
FDA to remove references to animal testing in safety regulations
The FDA has issued a final rule that would remove references to animal studies in its drug safety regulations, as part of a larger effort across HHS to reduce what it calls “unnecessary animal testing” in biomedical research.In addition to the new FDA …
How women can step into leadership roles in medicine
CHICAGO — According to WHO, women represent 67% of the global health and social care workforce, providing essential health services to approximately 5 billion people worldwide.However, research has shown that fewer than 30% of women hold senior leaders…
Ophthalmology Foundation focuses on blindness worldwide
Preventing blindness worldwide requires teamwork between industry veterans and ophthalmologists who are willing to offer their time to strengthen education across the globe. The Ophthalmology Foundation aims to make this a reality.“Everybody gives thei…
Q&A: A 5-step approach to setting achievable goals
CHICAGO — SMART goals — an approach centered on making objectives specific, measurable, achievable, relevant and time-bound — provide a useful framework for personal growth, a speaker at the Women in Medicine Summit said.However, before setting a SMART…
Q&A: A 5-step approach to setting achievable goals
CHICAGO — SMART goals — an approach centered on making objectives specific, measurable, achievable, relevant and time-bound — provide a useful framework for personal growth, a speaker at the Women in Medicine Summit said.However, before setting a SMART…