Source: Patient Preference and Adherence
Area: Evidence > Medicines Management > References
Purpose: This study summarises findings from objective assessments of compliance (or adherence) and persistence with ocular hypotensive agents in patients with glaucoma and ocular hypertension.
Design: Systematic literature review.
Methods: A PubMed and reference list search was conducted across publication years 1970-2010, using these terms and variants: 'compliance', the equivalent term 'adherence' and 'persistence' in patients with these conditions and therapies. Summaries of selected studies were stratified by measurement method (electronic monitor, prescription fills review, medical chart review). Measures of central tendency across studies were calculated for commonly-reported compliance or persistence measures.
Results: 58 articles met all inclusion/exclusion criteria: measurement of compliance - electronic monitoring (7 studies reported in 14 articles), measurement of compliance/persistence - prescription records (36 studies in 38 articles) and ...
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