Author: Healio ophthalmology

Povidone-iodine protocol reduces risk of post-injection endophthalmitis

BOSTON — Additional povidone-iodine given after placement of a lid speculum can significantly decrease the incidence of post-injection endophthalmitis, according to a speaker at the American Society of Retina Specialists meeting here.Joshua D. Levinson, MD, and colleagues at the Retina Group of Washington, D.C., concluded that such a measure was helpful after analyzing the effect of different aseptic protocols on the incidence of endophthalmitis following intravitreal injection.

Cytogenetic abnormalities correlated with clinical features of uveal melanoma

BOSTON — It takes teamwork to manage uveal melanoma, Carol L. Shields, MD, told colleagues at the American Society of Retina Specialists meeting,Citing 8-year experience with personalized prognosis of uveal melanoma based on genetic profile in 1,059 patients, recently published in Ophthalmology, Shields said she and coworkers found the strongest predictor of patient prognosis depends on chromosomal status, particularly chromosomes 3, 6 and 8.

Central retinal thickness improves with Iluvien implant in previously treated eyes

BOSTON — Central retinal thickness values improved after exposure to fluocinolone acetonide implant in eyes previously treated for diabetic macular edema, according to a study. However, steroid-induced ocular hypertension can occur despite a negative steroid challenge at baseline, with the baseline use of topical glaucoma therapy potentially confounding assessment of the steroid response, Sumit P. Shah, MD, FACS, said in a paper presentation at the American Society of Retina Specialists meeting.

Vitreoretinal surgery improves outcomes in juvenile retinoschisis

BOSTON — Vitreoretinal surgery helped improve visual outcomes in most patients with posterior segment complications of X-linked juvenile retinoschisis, according to a study.“Visual impairment in cases of congenital retinoschisis is usually very often seen because of the early macular involvement, but the surgical intervention is not required in more than 10% to 15% of these cases,” Parveen Sen, MBBS, MS, said at the American Society of Retina Specialists meeting. Sen and colleagues conducted a retrospective consecutive case series of 30 eyes of 25 patients with congenital retinoschisis who underwent surgery (Read more...)

Long-term anti-VEGF therapy maintains visual improvements

BOSTON — Long-term treat-and-extend anti-VEGF therapy maintains vision in some patients, even after 8 years and more than 50 injections, according to a study presented here“Consistent use of anti-VEGF therapy can provide long-term maintenance of vision in patients with neovascular AMD in a typical retina practice,” David Adrean, MD, said in a paper presentation at the American Society of Retina Specialists meeting.

PUBLICATION EXCLUSIVE: Addressing the ‘you’ve got to go, doctor’ elephant in the room

“The FBI Academy teaches new agents that the best predictor of future behavior is past behavior.”– Ronald KesslerIn boating circles, they say the best 2 days in a sailor’s life are when he buys a boat and when he gets rid of it. This might not be too far off the mark in ophthalmology. Adding a new doctor is always cause for celebration. But about half of the time so, too, is the removal of the same provider for one reason or another.

ASCRS to celebrate National Sight Week in October

National Sight Week will be observed from Oct. 15 to 21, the American Society of Cataract and Refractive Surgery Foundation announced. The weeklong celebration of volunteerism is meant to encourage members of the ASCRS Foundation’s Operation Sight network to contribute one or more cataract surgeries to assist uninsured or underinsured patients, according to an ASCRS Foundation press release.

Omeros reports $14.4 million loss in second quarter

Omeros reported a $14.4 million net loss, or $0.33 per share, in the second quarter of 2017 compared with a net loss of $12.6 million, or $0.32 per share, in 2016’s second quarter.Total revenues increased from $10 million a year ago to $17.2 million, all related to sales of Omidria, according to a company press release. Omidria revenue increased 40% on a sequential quarter-over-quarter basis.

AGTC files investigational NDA for X-linked retinitis pigmentosa gene therapy

Applied Genetic Technologies Corporation has filed an investigational new drug application with the FDA to begin a phase 1/2 clinical trial of its gene therapy candidate for X-linked retinitis pigmentosa, according to a company press release.X-linked retinitis pigmentosa, caused by mutations in the RPGR gene, is an inherited condition that causes progressive vision loss. In preclinical data, AGTC’s investigational gene therapy has slowed the loss of visual function in canines with X-linked retinitis pigmentosa, according to the release.

Staring at eclipse may cause solar retinopathy

Remember when you were a kid and you used a magnifying glass to concentrate the sun’s energy to burn paper? Solar retinopathy is like that except it is the fovea that is getting burned, according to one expert.“Solar retinopathy occurs when a person looks at the sun for a prolonged period of time, with the light rays focused on the macula,” Sunir J. Garg, MD, told Healio.com/OSN of the effects of sun gazing. “That causes light-related damage to the photoreceptors and retinal pigment epithelium.”

FDA clears Optovue’s epi-mapping software

Optovue’s epithelial thickness mapping software has become the first to be cleared by the FDA for quantitative measurements of the epithelial and stromal layers of the cornea, according to a company press release. Aiding in the diagnosis, documentation and management of ocular health and diseases, epi-mapping provides epithelial thickness information in a fast, non-contact exam, the release said. It is available through the iVue and iFusion OCT systems.