Patients taking glucagon-like peptide-1 agonists were more likely to progress from nonproliferative diabetic retinopathy to proliferative disease or diabetic macular edema than those who took sodium-glucose cotransporter-2 inhibitors. Medscape Medic…
Author: Medscape
Biosimilars Comparable to Aflibercept in Macular Disease
Phase 3 registration trials found the comparability of two biosimilars to reference aflibercept in terms of efficacy, safety, pharmacokinetics, and immunogenicity. Medscape Medical News
Higher Aflibercept Dose Safe as 2 mg
The PULSAR trial of a higher dosage formulation extended the treatment interval to 12 or 16 weeks. Medscape Medical News
Study Shows Vision, Anatomy Stable With Port System for AMD
Recalled in 2022, a port delivery system for ranibizumab to treat wet AMD demonstrated that vision and retinal anatomy remained stable in patients who had the device for 5 years. Medscape Medical News
Study: AMD Gene Therapy Demonstrates Vision Stabilization
An early gene therapy trial reported maintenance of vision, reduced retinal inflammation, and detectable therapeutic protein levels 9 months after treatment for age-related macular degeneration. Medscape Medical News
Are AI-Powered Skin-Check Tools on the Horizon?
Primary care might be the first setting where AI-driven tools allow for broader access to effective melanoma screening, amid continuing challenges in developing consumer apps for this purpose. Medscape Medical News
From Chronic Care to Zebras: Clinical Pearls in Uveitis
Nisha Acharya, MD, advocated long-term treatment for chronic or recurrent uveitis, exploring less-common causes, and multimodal imaging. Medscape Medical News
ASRS 2023
Read clinically focused news coverage of key developments from ASRS 2023 Medscape Ophthalmology
New Approaches for Diabetic Keratopathy in the Eye?
Findings also have implications for treating other diabetes-related wound healing conditions such as foot ulcers. Medscape Medical News
New Guide for Treating Vascular Birthmarks With Lasers
The first consensus guideline has been released for the laser treatment of vascular birthmarks. Medscape Medical News
Pediatric RIME: Report Describes Case Triggered by Norovirus
"I do feel like we’re seeing more cases and from a more diverse number of pathogens," says A. Yasmine Kirkorian, MD. MDedge News
Retina Group Warns on Complications From New GA Drug
The American Society of Retina Specialists has reported six cases of vasculitis not seen in clinical trials. Medscape Medical News
Humira Biosimilars: Five Things to Know
The launch of eight adalimumab biosimilars so far this year ended Humira’s 20-year monopoly, but it’s not clear yet if these discounted drugs will save patients money. Medscape Medical News
Dermatologic Therapies and the Eyes: Tips from a Specialist
Despite the potential for serious ophthalmic side effects from steroids and biologics in children, the actual risks are low to none when treatments are employed appropriately, says Sara Grace, MD. Medscape Medical News
Gene Therapy Promising for Hereditary Vision Loss
Patients with a progressive form of Leber hereditary optic neuropathy (LHON) that causes rapid vision loss experienced improvement in their eyesight with an experimental gene therapy. Medscape Medical News
Aging and Type 1 Diabetes: ‘Complete Picture’ 40 Years On
The Diabetes Control and Complications Trial (DCCT) and its follow-on observational study EDIC continue to provide new insights into type 1 diabetes as the study participants age. Medscape Medical News
New Medicare Rule Streamlines Prior Auth in MA Plans
CMS seeks to ensure people in Advantage plans have the same access to necessary care as those in traditional Medicare. The agency also cracked down on Medicare Advantage marketing for "sowing confusion." Medscape Medical News
Deadly Bacteria in Recalled Eyedrops Can Spread Person-to-Person
Scientists are concerned that the once rare treatment-resistant bacteria found in the eyedrops can spread person-to-person. The bacteria clings to sink drains, water faucets, and other moist places. WebMD Health News
Ocular Toxicity With New Drugs for Gynecologic Cancers
Antibody-drug conjugates are a promising new option for gynecologic cancers, but they have a variety of ocular or vision-related adverse events that need to be appropriately monitored and managed. Medscape Medical News
Medical Device Maker, Surgeon to Pay $46M in Kickback Scheme
The kickback settlement involves a surgeon and two leading ophthalmology device suppliers. Experts say physicians accepting vacations and other perks from manufacturers could face similar penalties. Medscape Medical News