Treatments for a rare retinal disease may be on the horizon after a new study has identified gene variants that cause a metabolic deficiency in the eye.
Author: The Medical News
Researcher uses alternative approach to find genetic drivers of rare eye disease
An analysis of thousands of genomes from people with and without the rare eye disease known as MacTel has turned up more than a dozen gene variants that are likely causing the condition to develop and worsen for a significant share of patients.
Study reveals biomarkers for the prognosis of gastric adenocarcinoma
Low plasma levels of protein TGFB1 and polymorphisms in gene TGFB1 act as biomarkers for the prognosis of gastric adenocarcinoma, according to a study led by the University Complutense of Madrid.
New study aims to develop alternative treatment for posterior eye diseases
Getting poked in the eye with a sharp object is a cringeworthy thought. However, many patients with posterior eye diseases — back of the eye diseases such as macular degeneration or diabetic retinopathy — undergo eye injections through the wall of th…
HPSE protein found to be a key regulator of cells’ innate defense mechanisms
Researchers at the University of Illinois Chicago have discovered that heparanase, HPSE, a poorly understood protein, is a key regulator of cells’ innate defense mechanisms.
Dry eye disease negatively affects patients’ health and vision related quality of life
Patients suffering from dry eye disease symptoms have a lower quality of life compared to those without symptoms, a new study reports.
Study investigates the prevalence of eye disease in adults with Down syndrome
Drs. Dimitrios Karamichos and Melissa Petersen at The University of North Texas Health Science Center at Fort Worth, are teaming with DownSyndrome Achieves (DSA) Biobank in Ohio to find clues about Keratoconus Dystrophy.
Research reveals link between proteins causing Alzheimer’s disease and age-related sight loss
Newly published research has revealed a close link between proteins associated with Alzheimer’s disease and age-related sight loss.
Phase 2 clinical trial is now open at Columbia to test gene therapy for dry macular degeneration
A phase 2 clinical trial is underway at Columbia University and NewYork-Presbyterian to test an investigational gene therapy for dry age-related macular degeneration, a progressive, chronic eye disease with no cure and a leading cause of blindness in t…
Central retinal artery occlusion can be a warning sign of other vascular issues
While most people think of strokes affecting the brain, they can also affect the eye. Central retinal artery occlusion (CRAO) is a rare form of acute ischemic stroke that occurs when blood flow is blocked to the main artery of the eye.
Study suggests a new way to detect heart disease through non-invasive tool
In a new study from Shiley Eye Institute at UC San Diego Health, researchers have identified a potential new marker that shows cardiovascular disease may be present in a patient using an optical coherence tomography (OCT) scan — a non-invasive diagnos…
Researchers identify a neural pathway critical to correcting behavioral errors
Mount Sinai researchers have identified a neural pathway through which the brain detects errors and guides subsequent behavioral improvement. This process, called cognitive control, is frequently dysregulated in a wide range of psychiatric disorders.
Scientists find new therapeutic approach to effectively treat age-related macular degeneration
Runt-related transcription factor 1 (RUNX1) has been linked to retinal neovascularization and the development of abnormal blood vessels, which result in vision loss in diabetic retinopathy.
Novel vectors reduce the risks associated with ocular gene therapies
Strategies based on the use of gene therapy to mitigate the effects of mutations that cause blindness are undergoing rapid development.
Addressing vision loss caused by diabetes
Diabetes and the Eye familiarize the readers with the relationship between diabetes mellitus and the visual system.
UIC researchers receive $10.15 million grant to develop treatment for dry eye conditions
Researchers at University of Illinois Chicago have been awarded a five-year, $10.15 million grant to develop a broad-spectrum immunomodulatory eye drop to treat patients with severe dry eye and ocular surface disease due to inflammatory and immune syst…
ASDS releases new recommendations for physicians performing injectable filler procedures
The American Society for Dermatologic Surgery (ASDS) multispecialty Soft-tissue Fillers Guideline Task Force has released its evidence-based recommendations for physicians performing injectable filler procedures.
Research shows how mutation linked with CLN3-Batten disease could lead to vision loss
Progressive vision loss, and eventually blindness, are the hallmarks of juvenile neuronal ceroid lipofuscinosis (JNCL) or CLN3-Batten disease.
New method can help evaluate potential sight-preserving properties
Scientists like the John A. Moran Eye Center’s Paul S. Bernstein, MD, PhD, know a special class of lipids, or fatty acids, found in the retina of the eye and in just a few other parts of the body play an important role in maintaining vision.
CU researchers awarded NEI’s 3D ROC prize to accelerate development of new therapies
Natalia Vergara, PhD, assistant professor of ophthalmology at the University of Colorado School of Medicine, has been awarded a 3D ROC prize by the National Eye Institute for her research team’s work to create better models to accelerate the developmen…