Advanced Cell Technology, Inc. announced today that it has filed an Investigational New Drug (IND) Application with the US Food and Drug Administration (FDA) to initiate a Phase I/II multicenter study using human embryonic stem cell (hESC) derived reti…
Category: Retina
Stem Cells in Ophthalmology Update 3: ACT Files IND to Treat Dry AMD
Furthering its lead in stem cell research in ophthalmology, Advanced Cell Technology Inc., announced today that it had filed an Investigational New Drug (IND) application with the U.S. Food and Drug Administration, to initiate a Phase I/II multicenter study for…
International clinical trial tests targeted drug for melanoma
Rush University Medical Center has just enrolled the first US patient in an international clinical trial testing a novel drug to treat certain kinds of melanoma, a deadly skin cancer that in its advanced stages currently has few effective treatments.
Photos of tiny blood vessels in the eye link air pollution to heart disease
By digitally photographing the tiny, hair-like blood vessels in the back of our eyes, researchers can now look directly at how small blood vessels like those that bring blood to the heart respond to air pollution.
How Effective Are AMD Drugs in Treating Diabetic Macular Edema?
At the AAO meeting in October, researchers reported that anti-VEGF drugs such as ranibizumab (Lucentis) and pegaptanib (Macugen) also appeared to be effective in improving visual acuity in patients with diabetic macular edema in a series of randomized, controlled trials. Full…
New Compact Digital Retinal Camera From Canon Receives Clearance from FDA
Canon announced last week that its CR-2 Digital Non-Mydriatic Retinal Camera had received 510(k) clearance from the FDA. Full Story →
Stargardt Disease To Be Treated With Embryonic Stem Cells in Trial Initiated by Advanced Cell Technology
Earlier this week, Advanced Cell Technology’s request to begin treating patients with Stargardt disease (also known as fundus flavimaculatus) with embryonic stem cells in a clinical trial was approved by the FDA. This will be the second trial using human…
Stem Cells in Ophthalmology Update 2: ACT Gets Go-ahead to Treat Stargardt’s
As I noted in my September report on the Use of Stem Cells in Ophthalmology, it was anticipated that either the program at The London Project to Cure Blindness or Advanced Cell Technology’s program to treat Stargardt’s disease would be…
VEGF Trap-Eye Treats Macular Degeneration
VEGF Trap-Eye is a new injectable medication that blocks VEGF for the treatment of wet macular degeneration. It may be as good as Lucentis, but not given as often.
Cochrane Review Anti-vascular endothelial growth factor for macular edema secondary to central retinal vein occlusion
Central retinal vein occlusion (CRVO) is a common retinal vascular disorder in which macular edema (ME) may develop, with a consequent reduction in visual acuity. The visual prognosis in CRVO-ME is poor in a substantial proportion of patients, especial…
Update on Combination Therapy in Wet Age-related Macular Degeneration
Which combination of drugs are considered to be most effective in treating wet ARMD? This new study looks at the therapeutic options. Expert Review of Ophthalmology Full Story →
Update on Implantable CentraSight Telescope
The CentraSight telescope for advanced macular degeneration has been FDA approved. Medicare still needs to decide if insurance will cover the costs and doctors still need training.
Popular Science names VisionCare’s Implantable Miniature Telescope for AMD ‘Best of What’s New’ 2010
VisionCare Ophthalmic Technologies, Inc., a developer of advanced visual prosthetic devices, today announced the Implantable Miniature Telescope (by Dr. Isaac Lipshitz), designed to improve vision in patients with end-stage age-related macular degeneration (AMD) is named “Best of What’s New” 2010…
Improved Options For Prosthetics And Treatments After Injury Offered By Brain-Machine Interfaces
Two experimental brain-machine technologies – deep brain stimulation coupled with physical therapy and a thought-controlled computer system – may offer new therapies for people with stroke and brain injuries, new human research shows. In addition, an animal study shows a…
Novel genetic mutation that causes the most common form of eye cancer discovered
A new study has revealed the discovery of a novel oncogene that is associated with uveal melanoma, the most common form of eye cancer.
pSivida Corp. to Present at the Maxim Group Growth Conference
WATERTOWN, Mass.–(BUSINESS WIRE)–pSivida to present at Maxim Group Growth Conference
Artificial retina more capable of restoring normal vision; animal study shows including retina’s neural ‘code’ improved prosthetic
Researchers have developed an artificial retina that has the capacity to reproduce normal vision in mice. While other prosthetic strategies mainly increase the number of electrodes in an eye to capture more information, this study concentrated on incor…
Safety and Efficacy of Ranibizumab in Diabetic Macular Edema (RESOLVE Study): A 12-Month, Randomized, Controlled, Double-masked, Multicenter Phase II Study
Ranibizumab is investigated as a possible new treatment for diabetic macular edema (DME). Diabetes Care
RXi Pharmaceuticals Reports Financial Results for the Third Quarter of 2010
WORCESTER, Mass.–(BUSINESS WIRE)–RXi Pharmaceuticals Corporation (Nasdaq: RXII) today reported its financial results for the third quarter ended September 30, 2010. RXi Pharmaceuticals is a recognized leader in RNAi-based therapeutic discovery and development with a comprehensive therapeutic platform that includes both…
‘Know About the Glow’ Campaign Aims to Stop Deadly Eye Disease in Children by Educating Parents
LOS ANGELES–(BUSINESS WIRE)–A glow in six-year old Benjamin Webber’s eye that appeared periodically in family photographs and was mistaken as a freckle, could have led to a lifetime of blindness. Fortunately for Megan Webber, she discovered that this glow could…