Purpose: To compare the effect of photodynamic therapy (PDT) and intravitreal ranibizumab in patients with polypoidal choroidal vasculopathy (PCV).Design: Randomized clinical trial.Methods: setting: Multicenter. study population: Total of 93 patients with treatment-naïve PCV. intervention: Patients were randomized to 2 arms. Patients in the PDT arm underwent a single session of PDT with verteporfin, and patients in the ranibizumab arm received 3 monthly ranibizumab injections at baseline. Additional treatment was performed as needed in each arm. main outcome measures: Primary outcome measurement was the proportion of patients gaining or losing more than 0.2 logarithm of minimal angle of resolution (logMAR) units from (Read more...)
Potential Causes of Incomplete Visual Rehabilitation at 6 Months Postoperative After Descemet Membrane Endothelial Keratoplasty – Corrected Proof
Purpose: To determine the various causes of unexpected incomplete visual rehabilitation at 6 months postoperative after Descemet membrane endothelial keratoplasty (DMEK).Design: Retrospective study of prospectively collected data at a tertiary referra…
Surgical Results of a Muscle Transposition Procedure for Abducens Palsy Without Tenotomy and Muscle Splitting – Corrected Proof
Purpose: To report a simple muscle transposition procedure without tenotomy or muscle splitting to treat abducens palsy.Design: Retrospective, interventional, consecutive case series.Methods: Nine patients with esotropia resulting from abducens palsy w…
Incidence of Pineal Gland Cyst and Pineoblastoma in Children With Retinoblastoma During the Chemoreduction Era – Corrected Proof
Purpose: To report on the frequency of cysts and tumors of the pineal gland in patients with retinoblastoma.Design: Observational retrospective case control study.Methods: setting: Institutional. study population: Four hundred eight patients treated fo…
Cost Comparison of Scleral Buckle versus Vitrectomy for Rhegmatogenous Retinal Detachment Repair – Corrected Proof
Purpose: To estimate and compare the costs of scleral buckle (SB) and pars plana vitrectomy (PPV) for treatment of rhegmatogenous retinal detachment (RRD).Design: Cost analysis based on published prospective data comparing SB and PPV for RRD repair.Met…
Age- and Hypertension-Dependent Changes in Retinal Vessel Diameter and Wall Thickness: An Optical Coherence Tomography Study – Corrected Proof
Purpose: To validate and evaluate the reliability of retinal vessel diameter measurements by optical coherence tomography (OCT). The effects of age and hypertension on vessel diameter were also examined.Design: Prospective, cross-sectional study.Methods: Two hundred thirty-eight eyes (238 subjects) with no ocular disease were included. Hypertension was present in 106 subjects and absent in 132 subjects. Spectralis HRA+OCT was used to scan a circular region around the optic disc. Outer and inner diameters of the 4 largest retinal arteries and veins were measured using OCT vascular wall reflections, and vessel wall thickness was calculated.Results: Intervisit, interexaminer, and interevaluator intraclass correlation coefficients (Read more...)