The ACP reviewed relevant studies but came to conclusions ‘not germane to the way we treat patients with type 2 diabetes today,’ says Dr Anne Peters.
Medscape Diabetes & Endocrinology
Tag: Diabetes & Endocrinology
Severe Thyroid Eye Disease Trials Show Hit-and-Miss Results
Adding mycophenolate mofetil to standard therapy for severe Graves’ orbitopathy shows some benefits in a post hoc analysis, but added radiotherapy has no effect and azathioprine benefits appear inconclusive. Medscape Medical News
Cataract Risk Highest in Younger Diabetes Patients
Diabetes patients face a twofold increased risk of developing cataracts compared with other patients. The risk rises to more than fivefold among those aged 45 to 54 years, new UK registry data suggest. Medscape Medical News
Anti-VEGFs Before Vitrectomy Helpful in Diabetic Retinopathy
Pretreatment with agents blocking vascular endothelial growth factor (anti-VEGF) offers several advantages in patients with complicated proliferative diabetic retinopathy (PDR) undergoing vitrectomy, according to pooled data. Reuters Health Information
Early-Onset Type 2 Diabetes ‘Not a Benign Condition’
Patients who were diagnosed with type 2 diabetes at age 18 to 45 (early-onset) had the highest prevalence of cardiovascular risk factors and worst glycemic control in a Danish national cohort. Medscape Medical News
CHMP Backs Once-Weekly GLP-1 Analog Semaglutide
The nod from the European Medicines Agency’s advisory panel follows approval by the US Food and Drug Administration. International Approvals
Artificial Intelligence Eyed as Diabetic Retinopathy Screen
A “deep learning system” can be taught to determine whether or not diabetic retinopathy is present across different ethnicities in a variety of settings.
Medscape Medical News
Mycophenolate Add-On Improves Graves’ Orbitopathy
Improvements seen in overall responses, various clinical measures compared with methylprednisolone alone. Medscape Medical News
Eyedrops for Diabetic Retinopathy Possible in the Future?
Contrary to hypothesis, neurodysfunction preceded microvascular impairment in only a minority of diabetic-retinopathy patients, but in that subgroup, neuroprotective eyedrops arrested disease progression. Medscape Medical News
Bariatric Surgery May Reduce Retinopathy Risk, Progression
Roux-en-Y gastric bypass reduced diabetic retinopathy risk regardless of postsurgery diabetes status in a two-phase trial; a second study confirms obesity-related microvascular changes are reversible. Medscape Medical News
J-DOIT3: ‘Aim for Near-Normal Metabolic Parameters’ in Diabetes
UPDATED // The large Japanese DOIT3 trial tells clinicians that optimal lipid, blood pressure, and, glycemic control are important to reduce microvascular and macrovascular complications in type 2 diabetes. Medscape Medical News
OCT Screening Cost-effective for Diabetic Retinopathy
It might make sense to screen everyone with diabetes for retinopathy using optical coherence tomography (OCT), new research suggests. Medscape Medical News
New SUSTAIN-6 Data Could Explain Retinopathy Worsening
Patients who developed retinopathy complications with semaglutide were more likely to have had preexisting retinopathy, poorer baseline glycemic control, and more robust glucose lowering in the trial. Medscape Medical News
Anti-VEGF Therapy May Reduce Diabetic Retinopathy Severity for Up to Two Years
Treating diabetic macular edema with anti-vascular endothelial growth factor (anti-VEGF) may lead to improvements in diabetic retinopathy severity for up to two years, particularly in patients with nonproliferative disease, researchers say. Reuters H…
Former Cancer Drug Very Promising for Graves’ Ophthalmopathy
Originally developed as a cancer drug, teprotumumab shows “unheralded” efficacy at relieving symptoms of thyroid eye disease, one investigator said.
Medscape Medical News
Targeted Retinopathy Screening Proposed in Type 1 Diabetes
Long-term data from the Diabetes Control and Complications Trial and its follow-up suggest retina exam frequency can be individualized based on initial degree of retinopathy and HbA1c. Medscape Medical News
Cardiovascular Safety of Ranibizumab for Diabetic Macular Edema Still Unclear
Uncertainty lingers about the cardiovascular safety of intravitreal ranibizumab injections for diabetic macular edema, a pooled analysis of clinical trials shows. Reuters Health Information
Intensive Glucose Control Lowers Microvascular Risks
Patients with type 2 diabetes who undergo intensive glucose lowering have a reduced risk of developing microvascular kidney and eye complications, a pooled analysis of four trials suggested. Medscape Medical News
Telemedicine Cuts Wait Time for Diabetic Retinopathy Screening
A primary-care-based telemedicine program has cut waiting time and improved screening rates for diabetic retinopathy in a large public-safety-net health system in LA County. Medscape Medical News
Many Youths Not Adequately Screened for Diabetic Retinopathy
Many youths with diabetes did not receive timely eye examinations to screen for diabetic retinopathy, a new study has found. Medscape Medical News