Columbia University scientists and collaborators at Rover Diagnostics have created a rapid PCR test that can be used at the point of care. Weighing in at two pounds, the portable device can rival the sensitivity and accuracy of traditional lab-based PCR testing equipment, but providing results in as little as 23 minutes. The new device […]
Tag: Diagnostics
Typhoid Detection Technique Improves Diagnostic Sensitivity
A team at the University of California Davis Health working with international collaborators have developed a new technique to detect typhoid and estimate its incidence in populations over time. The approach requires only a drop of blood from a finger prick and involves measuring levels of antibodies against two antigens: Hemolysin E (Hlye) and Sal (Read more...)
Photonic Technique for Deeper Fluorescent Sensors
Researchers at MIT have developed a method that lets them read the signal from fluorescent sensors that are as deep as 5.5 centimeters in tissue. Previously, it was very difficult to get a good signal from a fluorescent sensor placed that deep, as fluorescence emitted by the tissue itself would muddy the signal. The new […]
Wearable Uses Microneedles to Track Metabolism
A team of researchers at the University of California San Diego created a wearable device that uses a disposable microneedle patch to continuously sample and analyze interstitial fluid. The wearable can measure glucose, alcohol, and lactate levels, all of which could be useful information for patients with diabetes. The disposable patch is attached (Read more...)
Wearable Sweat Sensor Warns of Impending Cytokine Storm
Researchers at the University of Texas at Dallas, in collaboration with a company called EnLiSense, developed a wearable electrochemical sweat sensor that can detect chemokines in sweat, alerting the wearer and clinicians to a viral or bacterial infection. The device also warns of an impending cytokine storm, where high levels of inflammatory molec (Read more...)
Smartphone App to Diagnose Neurological Disorders
A team at the University of California San Diego has developed a smartphone app that can precisely measure changes in pupil size as a potential method to assess a variety of neurological conditions and disorders, including Alzheimer’s disease and ADHD. The technique relies on the near-infrared cameras that newer smartphones use for facial rec (Read more...)
Wireless Data Transfer for Implanted Devices Using Ionic Communication
Researchers at the Columbia University School of Engineering and Applied Science have developed a new method for implanted devices to communicate with the outside world that exploits the ions that are naturally present in our tissues. Ion-rich tissues store potential energy, and in this paradigm an implanted device would alter this stored energy wi (Read more...)
Multiplex Immunoassay for Dengue Diagnosis
Researchers at the University of Reading in the UK created a rapid multiplex immunoassay for the detection of Dengue fever. The technology, which the researchers call the Cygnus system, aims to provide improved sensitivity compared with lateral flow tests and improved convenience and speed compared with conventional lab tests. As a point-of-care de (Read more...)
Multi-Purpose Sensor for Rapid, Accurate COVID-19 Testing
Researchers at Johns Hopkins University developed a COVID-19 testing technology that is based on surface enhanced Raman spectroscopy (SERS) coupled with machine learning. The technique does not require sample preparation or special training and can deliver results in as little as 25 minutes, with an accuracy that is comparable to that of PCR, the c (Read more...)
Magnetic Tentacle Robot Travels Deep into Lungs
Researchers at the University of Leeds in the UK have created a magnetic “tentacle robot” that is just 2 mm in diameter, which they hope will be able to navigate through some of the smallest airways in our lungs. At present, a bronchoscope is used to investigate the lungs, but this cannot pass into very […]
Smartphone App Calculates Genetic Risk of Coronary Artery Disease
Researchers at the Scripps Research Institute in California have developed a smartphone app that can calculate a user’s genetic risk of coronary artery disease. The app can import genetic information from a commonly used genetic testing service, 23andMe, and provide a personalized risk assessment of coronary artery disease. In tests so far, u (Read more...)
Acoustic Fabric Listens to Heart and Breathing, Works as Hearing Aid
Researchers at MIT have created an “acoustic fabric” that can listen to its surroundings and convert the vibrations made by sound into electrical signals, much like the human ear or a microphone. The technology consists of piezoelectric fibers that are woven into the fabric, and the resulting machine-washable material could prove useful (Read more...)
Optical Probe Measures Dental Plaque Acidity
A team at the University of Washington have developed an optical probe that can detect the acidity of dental plaque. The acidity created by bacteria within plaque causes cavities, and knowing which areas of the teeth are particularly acidic could help dentists to predict where cavities are likely to arise. The knowledge could help someone [… (Read more...)
Microfluidic Device for Quick and Accurate SARS-CoV-2 Testing
Researchers at the Institute of Photonic Sciences in Barcelona, Spain, have created a microfluidic chip that can detect the SARS-CoV-2 virus in less than 30 minutes, and with a similar level of accuracy as the current gold-standard test, PCR. The technology combines the speed of antigen tests with the accuracy of PCR and may be […]
Blood Clotting Test on a Smartphone
Researchers at the University of Washington have developed smartphone-based technology that can allow someone to perform a blood clotting test at home. The technology is low-cost and easy to use. The test involves placing a drop of blood into a plastic attachment that can be viewed by a smartphone camera. The smartphone then vibrates the […]
(Read more...)Quick and Accurate COVID Test Uses LAMP Assay
Researchers at the University of Washington developed a new COVID testing technology that can provide accurate results in as little as 30 minutes. The technology intends to be a bridge between PCR tests, which are accurate but slow, and antigen tests, which are rapid but suffer from reduced accuracy. The system provides results straight to [&hellip (Read more...)
Cheap and Portable COVID-19 Test Lab
Researchers at Queen Mary University of London have created a low-cost, portable COVID testing kit intended for use in remote, low-resource regions of the world. They describe the approach as a lab-in-a-backpack, and it makes use of a recycled computer hard-drive as a centrifuge. The test assay relies on loop mediated isothermal amplification (LAMP (Read more...)
Automatic Blood Smear Preparation for Reliable Malaria Diagnosis
Researchers at Cambridge and Bath universities in the UK, along with colleagues at the Ifakara Health Institute in Tanzania, have created two devices, called autohaem, that assist in creating blood smears, a common technique for diagnosing malaria. A blood smear involves manually smudging a drop of blood across a microscope slide to allow observati (Read more...)
Quantum Sensor to Detect SARS-CoV-2 More Accurately
Researchers at MIT have designed a quantum sensor to detect SARS-CoV-2. While the device is still theoretical, the researchers have used mathematical simulations to show its potential, and the data and design indicate that it may be faster, more accurate, and less expensive than the current gold-standard technique, PCR. The system is based on nanod (Read more...)
O2Ring Keeps an Eye on Your Blood Oxygen Level: A Medgadget Review
We have all been living through a life-altering pandemic. As a result, words such as “oxygenation” and “pulse oximetry” have become mainstream and the general public has increased the use of pulse oximeters. This should come as no surprise since hypoxia (i.e., low blood oxygen level) is one of the hallmarks of COVID-19 pneum (Read more...)