Researchers at the Wyss Institute at Harvard University have developed a microfluidic chip that can recreate some of the features of radiation-induced lung injury. The lungs are very sensitive to radiation, and this can limit the application of radiotherapy to treat cancer. Accurately modeling radiation-induced lung injury could assist in developin (Read more...)
Tag: harvard
Microneedle Skin Patch Measures Cancer Biomarkers
Researchers at the Harvard Wyss Institute have developed a technique that lets clinicians to characterize and monitor melanoma. The system involves using a microneedle patch that can draw deep interstitial fluid into itself through a series of penetrating hyaluronic acid needles. The needles can later be dissolved to release the biomarkers into a t (Read more...)
3D Printed Heart Muscle Beats
Researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences have developed a technique that allows them to 3D print a heart ventricle, that can then go on to beat rhythmically. The technology could allow researchers to create heart models to test new cardiac drugs and may even pave the way for […]
Biomaterial Injection Combines T Cell and Cancer Vaccine Treatments
Researchers at the Harvard Wyss Institute have developed an anti-cancer biomaterial treatment that combines adoptive T cell therapy and cancer vaccine technology to treat solid tumors. The researchers have called their technique SIVET, which is short for “synergistic in situ vaccination enhanced T cell”. The approach combines local delivery of cyto (Read more...)
Ovarian Organoids to Study Reproductive Health
Researchers at the Harvard Wyss Institute are collaborating with a biotechnology company called Gameto to develop human ovarian organoids that will allow the study of reproductive and other health issues using tissues that closely mimic those in human patients. Another application may lie in allowing people with fertility issues to conceive. To dat (Read more...)
Artificial Ventricle Mimics Helical Muscle Fibers
Researchers at Harvard developed a technique that lets them recreate the helical arrangement of cardiac muscle fibers within the heart ventricles in a bioengineered construct. The breakthrough could pave the way for artificial bioengineered hearts. The researchers used a technique called Focused Rotary Jet Spinning (FRJS) that allows them to deposi (Read more...)
Microfluidic Chip Models Inflammatory Intestinal Disease
Researchers at Harvard’s Wyss Institute have modeled Environmental Enteric Dysfunction (EED), a childhood inflammatory intestinal disease, on a microfluidic chip and gained new insights into the genetic changes underlying the condition. This is the first in vitro model of the disease, and highlights the power of organ on a chip systems to pro (Read more...)
Endoscopic Surgery Using Steerable Lasers
Applying an energy source, such as a laser, to cut through or cauterize tissue is already widely used in external surgeries, such as laser eye surgery, but using this technology safely and accurately during minimally invasive internal procedures is difficult. Current endoscopic technology does not permit lasers to be steered and manipulated with su (Read more...)