Researchers from the Radboud University Medical Center in The Netherlands have trialed cooling vests, originally designed for elite athletes, in nursing staff who have to put in long shifts in COVID-19 wards wearing full personal protective equipment (PPE). While essential, the protective equipment can lead to significant discomfort in the form of (Read more...)
Tag: Materials
10 Second COVID Antibody Test on a Chip
Researchers at Carnegie Mellon University have developed a microfluidic chip that can provide rapid COVID-19 antibody tests. The electrochemical test can detect very low concentrations of antibodies in blood samples, and transmits the results to a smartphone. The test could help to measure patient responses to vaccines and determine if they have be (Read more...)
3D Imaging Illuminates Internal Structure of Brain Spheroids
Researchers at the Wyss Center in Geneva and collaborators have developed novel imaging and labeling techniques to view the internal structure of brain spheroids, and observe the morphology of single neurons in 3D. Brain spheroids, which the researchers term “mini brains,” are a cluster of different types of brain cells, and are culture (Read more...)
Magnetic Nanoparticles Deliver Chem and Heat Cancer Cells for Synergistic Effects
Researchers at University College London have shown that tiny magnetic nanoparticles could enhance cancer treatment. The particles can deliver chemotherapy drugs to cancer cells and also produce a mild heating effect when stimulated with an external alternating magnetic field. Combining particle-mediated heat treatment and chemotherapy resulted in (Read more...)
Sensor Converts Forearm Signals to Control Prosthetic Hands
Researchers at the University of California, Berkeley have developed a wearable sensor that can measure electrical signals in the forearm and use AI to correlate them with hand gestures, such as the movements of individual fingers. The team demonstrated that the system can control a robotic prosthetic hand and that it may provide a way […]
Artificial Attachments for Immune Cells Help Kill Tumors
Though immune cells have the capabilities to kill cancer cells, they’re often thwarted by cancer’s ability to evade detection. Researchers at Pennsylvania State University have now developed engineered natural killer cells that have a much better ability to find and kill cancerous cells. “We explored a novel method to engineer nat (Read more...)
Radiotherapy to Prevent Recurrence Post Brain Tumor Excision: Interview with Matthew Likens, President and CEO of GT Medical
GT Medical Technologies, a company based in Arizona, has developed the FDA-approved GammaTile system, which can provide localized radiation therapy for brain tumor excision sites. Its goal is to reduce tumor recurrence and enhance patient survival. The treatment consists of radiation seeds encased in a collagen substrate. These are easy to place at (Read more...)
Microbubbles Deliver Drugs Directly to Tumors
When fighting cancerous tumors, all too often the very drugs that can destroy a lesion tend to have significant negative effects on the rest of the body. Doses have to be maintained at moderate levels to avoid side-effects that are even worse than the disease. In light of this, researchers have been trying to develop […]
Interlocking Metals and Polymers for Magnetically Controllable Therapeutic Microrobots
Researchers at ETH Zurich have developed a technique to create tiny microrobots with interlocking polymer and metal parts that can be controlled using magnetic fields. The magnetic metal components can move within the polymer frame, providing locomotion, and the tiny bots are small enough to traverse blood vessels, potentially functioning as vehicl (Read more...)
Hydrogel Contact Lens Measures Biomarkers in Tears
Researchers at the Terasaki Institute in Los Angeles have developed a prototype of a contact lens that can assist with tear sampling for diagnostic purposes, and to also improve tear flow to potentially prevent dry eye disease. The hydrogel lens contains microchannels through which tears can travel and testing chambers where electrochemical and col (Read more...)
Highly Realistic 3D Printed Human Hearts
Physical models of organs and tissues have many uses in clinical medicine, particularly when preparing for challenging surgeries. Naturally, the heart is commonly modeled using 3D printing to most closely mimic the nuances of unique patient anatomies. This is useful when preparing for procedures such as mitral valve repairs, but typically this is a (Read more...)
Red Blood Cells Deliver Nanoparticles to Provoke Immune Response to Lung Metastases
Researchers at Harvard’s Wyss Institute have developed a way to deliver immune-stimulating agents to lung metastases. Their system involves nanoparticles loaded with an immune-stimulating agent that are attached to red blood cells. When injected into the blood stream, the red blood cells shed the nanoparticles as they squeeze through the narr (Read more...)
Stretchable Fiber-Optic Sensors for Skin-Like Sensation
Researchers at Cornell University have developed stretchable sensors that can detect sensations such as strain, pressure, and bending, much like human skin. Deformation is measured through changes in optical paths within the flexible fiber optic sensors. By providing a sense of ‘touch’, the sensors could provide additional functionality (Read more...)
Elastomeric Respirator Mask Senses Fit and Filter Saturation
Researchers at Brigham and Women’s Hospital and Massachusetts Institute of Technology have designed a new respirator, conceived as an improvement on standard N95 masks. The transparent respirator contains sensors that allow users to know if the mask is fitting snugly and alerts them when the filters need to be replaced. The mask, called the t (Read more...)
Implantable Biodegradable Sensor Measures Gases Inside The Body
Researchers at Penn State have developed an implantable sensor that can measure levels of NO and NO2 gases in the body, both of which are medically relevant. Consisting of silicon and magnesium, the sensor is flexible and completely biodegradable, and so does not need to be removed after implantation. Measuring levels of NO and NO2 […]
Flexible Patch Monitors and Treats the Beating Heart
Researchers at the University of Houston and colleagues have developed a flexible epicardial patch which can monitor heart function and even administer treatments, such as thermal ablation and heart pacing. The device can harvest power directly from the movement of the beating heart and its flexibility means that it conforms well with the epicardia (Read more...)
Microfluidic Device to Test Pancreatic Cancer Drugs
Certain varieties of pancreatic cancer exhibit multiple tumor cell subtypes that work, somewhat mysteriously, to quickly become resistant to chemotherapy agents. Researchers at Purdue University have now built a unique microfluidic device that can be used to test a cancer drug on multiple tumor cells subtypes. Using this technology the researchers (Read more...)
Octopus-Inspired Sucker for Tranplanting Cell Sheets
Researchers at the University of Illinois have developed a ‘sucker’ to pick up and transfer thin cell or tissue sheets that are intended for therapeutic purposes, such as wound healing or tissue grafting. Inspired by octopus suckers, the device can gently manipulate the delicate sheets without causing damage, and uses heating and a temp (Read more...)
Supportive Gel Allows for Bioprinting of Complex Shapes
Researchers at Penn State have developed a supportive gel that allows for printing of complex shapes using cell aggregates. The gel provides a supportive matrix during the printing process, and permits the researchers to place the aggregates wherever they want. This technique could pave the way for printed replacements for tissues and organs. Biopr (Read more...)
Tiny Robots Walk Through Colon to Deliver Drugs, Sample Tissue
Delivering drugs to internal organs and tissues is usually achieved through ingested medications, but these are often diluted and intercepted before enough can reach the intended destination. Targeted delivery is preferred but usually very difficult to accomplish, particularly when there’s a lot of fluids and movement. This is the case with t (Read more...)