Researchers at Rutgers University have developed a microchip that can perform real-time measurements of stress hormone levels in a drop of blood. The technology could provide a replacement for bulky and expensive lab tests for such hormones, and allow patients to monitor their stress levels more easily. The chip includes tiny wells that contain ant (Read more...)
Tag: Medicine
Blood-Brain Barrier on a Chip for Neuro Drug Testing
Researchers at the KTH Royal Institute of Technology in Stockholm, Sweden, engineered a blood-brain barrier on a chip using human-derived stem cells. The device closely mimics the blood-brain barrier and allows the researchers to study its function and the effect of drugs without having to use experimental animals. By incorporating sensors, the chi (Read more...)
Sweating E-Skin for Long-Term Health Monitoring
Researchers at MIT have developed an e-skin technology that contains artificial sweat ducts. The ducts prevent sweat accumulation underneath the e-skin, helping to prevent interference with built-in sensors. Incorporating a kirigami-style design, the material conforms to human skin but maintains a high porosity and reduced sweat accumulation. The d (Read more...)
Fluorescent mRNA to Track, Optimize Delivery
Researchers at Chalmers University of Technology in Sweden and collaborators created a technique to produce fluorescently labeled mRNA, allowing them to track its entry and distribution into cells. Using such molecules could help scientists develop better ways to deliver mRNA therapeutics into the body, potentially playing a vital role in the new w (Read more...)
Face Mask Detects SARS-CoV-2
Researchers at the Harvard Wyss Institute and MIT have developed a face mask that can detect SARS-CoV-2 in a wearer’s breath. The mask employs freeze dried molecular components including CRISPR-based technology, and a lateral flow assay strip to detect the virus and alert the wearer. To initiate the test, the wearer simply presses a button [& (Read more...)
Microarray Rapidly Identifies Antibodies Against SARS-CoV-2
Researchers at the Technical University of Munich in Germany have developed a sensitive and inexpensive microarray technology that can rapidly identify antibodies against the SARS-CoV-2 virus in blood or serum samples. The test can provide a result in as little as eight minutes, but the researchers believe that this can be further reduced to just [ (Read more...)
Rapid Diagnosis of Infectious Disease at Point of Care: Interview with Shawn Marcel, CEO of Torus Biosystems
Torus Biosystems, a medtech startup that spun out of Harvard’s Wyss Institute for Biologically Inspired Engineering, has developed the Synestia system, a point of care diagnostic tool for infectious disease. The system aims to provide rapid, point-of-care identification of pathogens, and incorporates microarray and qPCR technology. &nbs (Read more...)
AI-Powered App Interprets HIV Test Results
Researchers at University College London and the Africa Health Research Institute have developed an AI-powered app that can interpret lateral flow tests for HIV. The technique involves taking an image of the test with a smartphone camera, and the app can tell whether the result is positive or negative simply by analyzing the image. As […]
Nanodecoys Bind SARS-CoV-2 for Destruction by Immune System
Researchers at North Carolina State University have developed a nanodecoy system that provides binding sites for the SARS-CoV-2 virus. The vesicles help to prevent the virus from binding to lung cells and lead to its eventual destruction by the immune system. The nanodecoys are derived from lung spheroid cells, and contain the angiotensin-convertin (Read more...)
Graphene Sensor for Rapid COVID-19 Detection
Researchers at the University of Illinois Chicago have developed a graphene-based sensor that can rapidly detect the SARS-CoV-2 virus. The system includes graphene sheets that are coupled with an antibody against the viral spike protein. When viral particles bind to the antibodies, they change the vibrational properties of the graphene sheets, and (Read more...)
Kirigami Stent for Localized Drug Delivery
Researchers at MIT have developed a kirigami-style stent that can provide localized drug delivery through needle-like projections that pop out when the stent is extended. The ‘spines’ on the stent’s surface deliver drug-loaded microparticles into the surrounding tissue, allowing for sustained drug release for an extended period. T (Read more...)
High-throughput 3D Bioprinting for Drug Development
Researchers at the University of California San Diego have developed a high-throughput technique for 3D bioprinting. Using the new technology, the researchers can very quickly print large numbers of custom tissue samples that are suitable for drug screenings. Their printing method can yield a 96-well plate with tissue samples in each well in as lit (Read more...)
Electrochemical Device Detects SARS‑CoV‑2 Spike Protein in 1 Second
Researchers at the University of Florida and the National Chiao Tung University in Taiwan have developed a microfluidic device that can detect the SARS‑CoV‑2 spike protein in a saliva sample within one second. The electrochemical device employs antibodies against the spike protein to detect the virus, and could allow for ultra-rapid COV (Read more...)
GARNET Pathogen Filter to Treat Sepsis: Exclusive with Nisha Varma, COO of BOA Biomedical
Sepsis is caused by an uncontrolled spread of infectious pathogens and release of toxins that can lead to systemic inflammation, multi-organ failure, and even death. The pathogens responsible for causing sepsis are usually difficult to identify, and patients are routinely treated with broad spectrum antibiotics. However, dead pathogens remaining in (Read more...)
Gene-Silencing Nanoparticles to Treat COVID-19
Researchers at City of Hope, a research center based in California, and Griffith University in Australia have collaborated to create a new experimental anti-viral therapy that can treat COVID-19. The therapeutic consists of small interfering RNA (siRNA) molecules encapsulated within lipid nanoparticles. When delivered into the bloodstream, the nano (Read more...)
Trojan Horse Virus Makes Tumors Destroy Themselves
Researchers at the University of Zurich have developed a virus-based therapy that causes a tumor to destroy itself. They modified an adenovirus, which is a common virus that typically infects the respiratory tract and which is already widely used in medicine, to deliver genetic material that codes for an anti-cancer protein. In a sneaky move, [&hel (Read more...)
Tiny Implantable Ultrasound Chip for Physiological Monitoring
Researchers at Columbia University have developed a microscopic implantable chip for physiological monitoring. It has a total volume of less than 0.1 mm3. To put that in perspective, the chip is as small as a dust mite, and can only be viewed using a microscope. The goal of this research was to create devices that […]
Hydrogel Wound Treatment Kills Antibiotic Resistant Bacteria
Researchers at Chalmers University of Technology in Sweden have developed an antibacterial hydrogel that can kill antibiotic-resistant bacteria. The material is conceived as a wound dressing, and is composed of antimicrobial peptides which are naturally produced by the immune system. The gel binds the peptides together and protects them, yet allows (Read more...)
Sweat Sensor for Non-Invasive Glucose Measurement
Researchers at the University of California San Diego have developed a sweat sensor that measures glucose levels on the skin and converts those readings into accurate blood sugar estimates. As glucose levels in sweat can vary from person to person, the sensor incorporates algorithms that personalize the measurement for each user, requiring finger-p (Read more...)
Implantable Pump Delivers Chemotherapy to Brain Tumors
Researchers at Linköping University, Sweden, and the Medical University of Graz, Austria have developed an electrical pump that can precisely deliver chemotherapeutic drugs into the brain. The technology is conceived as being implantable into brain tumor resection sites to deliver localized chemotherapy over extended periods. It is hoped that (Read more...)