Tag: Nanomedicine

Magnetically Controlled Microbots for Drug Delivery and Hyperthermia Therapy in Cancer

Researchers in Daegu Gyeongbuk Institute of Science and Technology in South Korea have developed biodegradable microrobots that can be magnetically controlled to deliver drugs and provide hyperthermia treatment at the site of a tumor. This latest research effort attempts to provide a delivery option for two different therapy pypes by creating biode (Read more...)

Nanoscale Light Manipulation for Detection of Tiny Pathogens

Viruses are so small that to be able to detect them using light you need instruments that work on the nanoscale. Sensors so perfect are very hard to make, as most manufacturing processes disrupt nanoscale structures. Now, a team at Purdue University has developed a way to combine 3D plasmonic nanoarrays, special light manipulation devices, [&hellip (Read more...)

Plugging Holes in Blood Vessels Caused by Nanoparticle Therapy

While targeting nanoparticles to attack cancer cells can be effective at reducing primary tumors, they tend to create tiny holes within blood vessel walls that let some cancer cells escape and metastasize elsewhere. This is a serious side effect that may limit the usefulness of many nanoparticle-based cancer therapies in the long run, so researcher (Read more...)

Gold Nanostars Help Design New Nanomedicines

Researchers from Northwestern University have developed a novel way to track how nanoparticles interact with cancer cells and whether they reach their tagets. The team’s work shows that if a nanoparticle targets cancer cells, it undergoes more rotational and translational movement compared to nanoparticles that cannot target cancer cells effe (Read more...)

Neurons Grow on Crosslinks of Carbon Nanotubes

Carbon nanotubes have a host of interesting properties. They are biocompatible and electrically conductive, so have been investigated as a possible material for growing nerve tissues. To make carbon nanotubes cooperate as desired, novel forms are required and researchers at SISSA (International School for Advanced Studies) and University of Trieste (Read more...)

LipoGlo Makes Bad Cholesterol Glow Inside Zebrafish

So-called “bad cholesterol” is a molecular complex of fat and protein. Specifically, the protein is Apolipoprotein-B, or ApoB, and the fat is cholesterol. While ApoB helps fat molecules to move around the blood vasculature, it is also what makes cholesterol stick to vessel walls, forming dangerous plaques that are one of the main causes (Read more...)

Artificial Protein Switch for Smart Cell Therapies

Researchers from University of California, San Francisco and the University of Washington have developed a new artificial protein switch, dubbed LOCKR. Their work demonstrates that the new switch can be used to control many intracellular processes, including mediating molecular traffic inside a cell, degrading specific proteins, and causing a cell (Read more...)

Using Microparticles to Measure Oxygen in Tissues

The field of tissue engineering is rapidly progressing, in large part thanks to hydrogel scaffolds that provide a comfortable home for new cells. A major issue that researchers bump against is tracking how well oxygen reaches freshly grown cells within such scaffolds, which can indicate how well the new cells are generally functioning. Now, researc (Read more...)

Self-Powered Microrobots Deliver Drugs to Tumors in the Gut

Treating tumors within the GI system is often a difficult challenge, frequently requiring invasive surgery. Scientists at Caltech have now developed self-propelled microrobots that can deliver drugs to precise spots within the intestines, and that can let clinicians monitor and control their activity. Besides drug delivery, the microrobots have the (Read more...)

Thin Microgels Encapsulate and Protect Therapeutic Cells

Cell-based therapies, such as those involving the delivery of stem cells, require a way to encapsulate cells inside a protective package in order for them to not be destroyed and washed out by the body. There have been successful attempts to contain therapeutic cells within hydrogels, but the resulting materials were bulky and could not […]

New Nanoparticles Help Spinal Cords to Heal Following Injury

When people damage their spinal cords, a lot of the long-term consequences often stem from the body’s overreaction to the injury. That’s because the blood-brain barrier protecting the spinal cord becomes compromised and overly aggressive immune cells flood in. Now, a team from the University of Michigan has developed a way of using intr (Read more...)

Tiny Nanowire Probes Measure Intracellular Electrical Activity

Researchers at the University of Surrey and Harvard University have developed tiny nanoprobes that can measure electrical signals inside cells, such as neurons and cardiac cells. Unlike previous technology for intracellular electrophysiology, the nanoprobes cause minimal destruction to the cells, and could pave the way for human-machine interfaces (Read more...)

Superhydrophic “Nanoflowers” for Biomedical Applications

Researchers from Texas A&M University have developed new nanomaterial with superhydrophobic properties. Their recent publication demonstrates that by controlling atomic-scale defects in their nanomaterial, they could use it to repel water and blood on glass, paper, and other common materials. This exciting development can lead to self-cleaning (Read more...)

Crystallized Drugs to Protect Implants from Immune Attack

Implantable medical devices that intimately interact with the human body are often subject to the immune system’s foreign body response (FBR). This creates scarring around the implants, reducing their functionality over time. Now, scientists at MIT have developed a way to embed crystallized immunosuppressant drugs into implantable devices so (Read more...)

Nano-emulsions for Drug Delivery Through Skin

Researchers from MIT have developed a new chemical nanoemulsion that can help deliver drugs through the skin. Their work demonstrates that, only by using a handful of FDA-approved materials, they can create nano-sized emulsions which turn to gels when they come in contact with the body. These nano-emulsions may have interesting properties for drug (Read more...)