In honor of Medscape’s 20th anniversary, Dr Julia Haller discusses advances in ophthalmology with her colleagues from the cataract, glaucoma, retina, and cornea services at Wills Eye Hospital. Wills Eye Hospital
Tag: Ophthalmology
FDA Says No to Lifitegrast for Dry Eye, Requests More Data
In a complete response letter, the FDA asked for another study on the experimental ophthalmic solution for dry eye and further information related to product quality. Medscape Medical News
Cataract Surgery and Postoperative Endophthalmitis
How does the risk for postoperative endophthalmitis with injectable IOLs compare with that of manually folded IOLs? The British Journal of Ophthalmology
Carotenoid-Rich Diet May Protect Against Advanced Eye Disease
Dietary components lutein and zeaxanthin reduced the risk for advanced age-related macular degeneration in a large prospective cohort. Medscape Medical News
Refractory Dry Eye Linked With Neuropathic or Systemic Pain
Subjective responses to artificial tears for dry eye differ based on the presence of neuropathic ocular and systemic pain, according to researchers. Reuters Health Information
The Many Facets of Dacryoadenitis
What are the common causes of lacrimal gland inflammation and how is it best managed? A new review discusses the etiology and treatment options. Current Opinion in Ophthalmology
AMD: Continued Anti-VEGF Treatment May Induce Response
Patients who do not initially respond to anti-VEGF treatment for age-related macular degeneration may do so if they continue receiving the same treatment for a longer course of therapy. Medscape Medical News
Sulfur Hexafluoride Use in DMEK Safe to 3 Years
Use of 20% sulphur hexafluoride for tamponade instead of 100% air in Descemet’s membrane endothelial keratoplasty led to similar patient outcomes but fewer graft detachments. Medscape Medical News
Eye Surgeon Found Guilty of Bogus Diagnoses and Surgeries
David Ming Pon, MD, lied to patients that they had age-related wet macular degeneration and then faked laser photocoagulation, according to federal prosecutors. Medscape Medical News
Eylea vs Lucentis for Treatment-Naive Neovascular AMD
A new study compares outcomes between these two drugs in previously untreated patients with neovascular AMD. How do they stack up? BMC Ophthalmology
Amiodarone Confers a Small Risk for Optic Neuropathy
Physicians should monitor visual symptoms in amiodarone users. Medscape Medical News
Laser Speckle Flowgraphy Can Assist in CRVO Prognosis
Correlating blood flow velocity to aqueous vascular endothelial growth factor concentrations offers insight into outcomes from central retinal vein occlusion. Medscape Medical News
AMD: Antihypertensives Do Not Prevent Neovascularization
Use of systemic beta blockers, angiotensin-converting enzyme inhibitors, and angiotensin receptor blockers was not different between patients with wet and dry age-related macular degeneration. Medscape Medical News
Solar-Related Eye Tumor Diagnosis Difficult in Low-Resource Settings
Clinical features do not reliably distinguish ocular surface squamous neoplasia (OSSN) from benign conjunctival lesions when histology can’t be evaluated, and toluidine blue vital staining is good for screening but not for diagnosis, a study from Kenya…
Intravitreous Melphalan Can Have Anterior Segment Toxic Effects
Intravitreous injection of melphalan can have toxic effects in the anterior eye segment in addition to well established effects in the posterior segment, a new study shows. Reuters Health Information
A Chance Finding of Pigmented Retinal Spots
A 6-year-old boy presents with lesions of the retinal pigment epithelium in one eye. Is this a benign finding or does it suggest a more serious disease? Medscape Ophthalmology
Diet, Exercise, Smoking, and Genes Interact in AMD Risk
Unhealthy lifestyle habits plus genetic risk factors can act synergistically to increase risk for age-related macular degeneration. Medscape Medical News
Anti-VEGF Therapy Before Steroids for Retinal Vein Occlusion
Aflibercept and ranibizumab should be the first-line options in the treatment of central retinal vein occlusion, according to one small study. Medscape Medical News
Pegpleranib Promising as Macular Degeneration Pretreatment
Pretreatment with the anti-PDGF pegpleranib increases the effectiveness of anti-VEGF therapy, according to a small pilot study, Medscape Medical News
‘Encouraging’ Real-life Data on Ranibizumab in Wet AMD
Most patients with age-related macular degeneration (AMD) in a ‘real-life’ study maintained their vision or continued to improve after 5 years of treatment with ranibizumab. Medscape Medical News