Dr Denis Poddubnyy discusses data from the AXIS study that inform his approach to diagnosing axial psoriatic arthritis. Medscape Rheumatology
Tag: Rheumatology
Uveitis May Flag Possibility of Axial Spondyloarthritis
Many patients with nongranulomatous acute anterior uveitis may be diagnosed with previously unrecognized axial spondyloarthritis after rheumatologic evaluation. Medscape Medical News
Fast Five Quiz: Difficult-to-Treat PsA
What do you know about difficult-to-treat and treatment-resistant psoriatic arthritis? Test yourself with this quick quiz. Medscape Reference
Zanubrutinib May Benefit Patients With IgG4-Related Disease
Zanubrutinib monotherapy may help shrink inflamed glands, ease symptoms, and is generally well tolerated in patients with immunoglobulin G4-related head and neck disease, a phase 2 study shows. Medscape Medical News
Elevated Interferon Alfa May Reveal Sjögren Disease Subtype
Elevated interferon alfa levels mark a subgroup of Sjögren disease, revealing immune changes years before diagnosis, and mice studies mirror these findings. Medscape Medical News
Uveitis Patterns Vary in Relation to Spondyloarthritis Type
Patients with peripheral forms of spondyloarthritis show a higher prevalence of different uveitis patterns than those with axial forms. Medscape Medical News
CCL19 as a Biomarker May Track IgG4-Related Disease Activity
CCL19 emerges as a promising biomarker that distinguishes active disease from treatment-induced remission and may help to identify relapsing disease in patients with IgG4-related disease. Medscape Medical News
Smoking May Lower Sjögren Disease Risk and Mask Pathology
Cigarette smokers have a significantly lower likelihood of being diagnosed with Sjögren’s disease, with histologic data showing less tissue damage and lower disease activity in smokers who have it. Medscape Medical News
Anifrolumab Improves Multiple Sjögren Disease Measures
Early data from the ANISE-II study show that the lupus-approved treatment may also work well in managing Sjögren disease. Medscape Medical News
Hydroxychloroquine Level Monitoring Can Boost Lupus Control
Weight-based dosing misses accounting for factors such as chronic kidney disease or chronic transaminitis, which could potentially accelerate toxicity risk or increase the risk for SLE flares. Medscape Medical News
Low-Dose Aspirin May Reduce Cardiovascular Risk in GCA
Low-dose aspirin initiated at diagnosis of giant cell arteritis is linked to a reduced probability of major adverse cardiovascular events at 1 year but also to an increased risk for major hemorrhage. Medscape Medical News
Treating IgG4-RD: How Far Will B-Cell Drugs Take the Field?
Post hoc analyses of pivotal MITIGATE trial show broad efficacy across patient subgroups with differing organ involvement and clinical characteristics. Medscape Medical News
Pediatric Rheumatologist Explains Updated ACR JIA Guidelines
The new draft guidelines favor earlier DMARD therapy with ‘much decreased reliance on glucocorticoids that have several side effects in growing children,’ said rheumatologist Susan Shenoi, MS. Medscape Medical News
PET/CT Can Catch Cranial GCA Missed by Doppler Ultrasound
Digital FDG PET/CT can pick up cranial giant cell arteritis that may be missed on ultrasound because of a lack of trunk large-vessel involvement. Medscape Medical News
Dry Eye Disease May Occur Years Before Autoimmune Disease
Dry eye disease affects many people across different autoimmune diseases, ranging in prevalence from about 23% to 81%, and appears about 3 years before diagnosis, a study finds. Medscape Medical News
FDA Makes Ianalumab Breakthrough for Sjögren Disease
Results from two clinical trials on ianalumab for Sjögren disease show favorable safety and adverse event outcomes, contributing to this designation. Medscape Medical News
FDA Makes Ianalumab a Breakthrough Therapy for Sjögren’s
Results from two clinical trials on ianalumab for Sjögren disease show favorable safety and adverse event outcomes, contributing to this designation. Medscape Medical News
Advice on Recognizing and Managing Sjӧgren Disease
Dr Nancy Carteron urges clinicians to learn to recognize how Sjӧgren disease could be hiding in plain sight and why early care is more essential than ever. Medscape
Advice on the Challenges in Managing Sjögren Disease
Dr Teja Kapoor urges early-career clinicians not to underestimate Sjögren’s disease, which requires thorough testing and multidisciplinary collaboration. Medscape
Overcoming Barriers in Sjögren Disease Care
Dr Teja Kapoor explores how cultural sensitivity and awareness can overcome barriers to timely Sjögren disease management in diverse communities. Medscape