Paloma Pharmaceuticals Update On Ocular Clinical And Oncology Programs
Paloma Pharmaceuticals, Inc. announced today updates on its age-related macular degeneration Phase I trials and oncology program. Palomid 529 (P529), Paloma Pharmaceuticals first-in-class allosteric dual TORC1/TORC2 dissociative inhibitor targeting the PI3K/Akt/mTOR pathway, has successfully completed the Company's first three cohorts of its Phase I intravitreal administration trial in patients with age-related macular degeneration (AMD). In addition, the National Eye Institute has treated its first patient in the Institute's own Phase I AMD trial administering P529 subconjunctival, "A Phase I Unmasked Study to Investigate the Safety and Tolerability of Subconjunctival Injections (Read more...)