Pfizer communication on risk of serious increase in intraocular pressure with intravitreal injection of excess volume of pegaptanib sodium (Macugen®)

Source: Pfizer
Area: News
Pfizer has issued a communication about a potential for injecting an excess volume of pegaptanib sodium (Macugen®) intravitreally. This risk has been identified in a clinical trial and in clinical practice. Two cases have been reported in which a volume of Macugen greater than the recommended volume (90 ?L) was injected into a patient's eye with a subsequent elevation of intraocular pressure (lOP). In both cases, the lOP became elevated to a level which required anterior chamber paracentesis.   The Company advises that to ensure the (Read more...)

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