The study’s primary endpoint was not met, but some benefits were seen. Medscape Medical News
Month: December 2012
Scientists Construct First Map Of How The Brain Organizes Everything We See
Our eyes may be our window to the world, but how do we make sense of the thousands of images that flood our retinas each day? Scientists at the University of California, Berkeley, have found that the brain is wired to put in order all the categories o…
Does transportation mode modify associations between distance to food store, fruit and vegetable consumption, and BMI in low-income neighborhoods?
By: fuller.daniel
Fluoroquinolones First for Bacterial Keratitis
Fluoroquinolones are a good first empiric treatment for patients with bacterial keratitis, according to a recent systematic review and meta-analysis. Medscape Medical News
Organizing The Eye’s Neurons
Johns Hopkins researchers A. R. Tomas and M. R. Deans have identified a protein needed for neuron organization in the developing retina. The team says that the study helps reveal how the healthy retina – the part of the eye that detects light – is bui…
Higher Visual Function
This fascinating review provides a neurobiological perspective on visual agnosias — disorders that impair the perception and recognition of color, words, objects, and faces. Practical Neurology
Decide by Dec. 31 Whether to Stay in Medicare, Societies Say
If Congress fails to avert cuts in Medicare reimbursement totaling almost 29%, the average family physician will lose $27,000 in revenue, according to the AAFP. Medscape Medical News
Prevalence of Sjogren’s Syndrome in Patients With Dry Eye
Are patients with aqueous-deficient dry eye at an increased risk for developing Sjogren’s syndrome? How is it best diagnosed? The British Journal of Ophthalmology
Eyes Might Have It for MS Drug Trial Measures (CME/CE)
(MedPage Today) — Active multiple sclerosis is associated with rapid thinning of part of the retina, making eye measures helpful in evaluating new therapies, researchers suggested.
Eyes May Reveal Multiple Sclerosis Progression
Retina thinning may reveal how rapidly multiple sclerosis is progressing, researchers from Johns Hopkins MS Center reported in the journal Neurology. The scientists explained that they referred to the thinning of “a layer of the retina in the eyes”…
Investigation of the Human Anterior Segment in Normal Chinese Subjects Using a Dual Scheimpflug Analyzer
Purpose:
To investigate anterior segment parameters in normal Chinese subjects and study factors influencing these parameters, such as age, gender, and laterality.
Design:
A prospective observational case series.
Participants:
A total of 291 normal subjects (582 eyes) were included.
Methods:
The anterior segment data were determined with a dual Scheimpflug analyzer.
Main Outcome Measures:
The corneal thinnest-point thickness (CTPT), corneal thinnest-point distribution (CTPD), central corneal thickness (CCT), corneal thickness (CT) in the central 10 mm diameter, pupil diameter (PD), pupil center distribution (PCD), anterior chamber depth (ACD), and anterior chamber (Read more...)
Diagnostic Capability of Lamina Cribrosa Thickness by Enhanced Depth Imaging and Factors Affecting Thickness in Patients with Glaucoma
Objective:
To determine the diagnostic ability of laminar thickness obtained using enhanced depth imaging (EDI) of the Heidelberg Spectralis optical coherence tomography (OCT) system (Heidelberg Engineering, Heidelberg, Germany) and the factors relat…
Vascular Endothelial Growth Factor Promotes Progressive Retinal Nonperfusion in Patients with Retinal Vein Occlusion
Objective:
Central retinal vein occlusion (CRVO) or branch retinal vein occlusion (BRVO) causes hypoperfusion, high levels of vascular endothelial growth factor (VEGF), macular edema, and loss of vision. Many patients also show areas of complete clos…
Effect of Lateral Decubitus Position on Intraocular Pressure in Glaucoma Patients with Asymmetric Visual Field Loss
Purpose:
To investigate the effect of the lateral decubitus position (LDP) on intraocular pressure (IOP) in glaucoma patients with asymmetric visual field loss.
Design:
Prospective, cross-sectional study.
Participants:
Ninety-eight eyes of 49 consecutive bilateral glaucoma patients with asymmetric visual field loss, divided into better eye and worse eye groups for calculation of mean deviation.
Methods:
Intraocular pressure was measured using a Goldmann applanation tonometer and rebound tonometer (Icare PRO; Icare Finland Oy, Helsinki, Finland) in each of the following positions: sitting, supine, right LDP, and left LDP. Visual field was (Read more...)
Associations of the C2-CFB-RDBP-SKIV2L Locus with Age-related Macular Degeneration and Polypoidal Choroidal Vasculopathy
Purpose:
To investigate the associations of the C2-CFB-RDBP-SKIV2L region with neovascular age-related macular degeneration (AMD) and polypoidal choroidal vasculopathy (PCV).
Design:
Cross-sectional, case-control association study.
Participants:
…
Predictors of Matching in an Ophthalmology Residency Program
Purpose:
To examine the characteristics of US medical students applying for ophthalmology residency and to determine the predictors of matching.
Design:
A retrospective case series.
Participants:
A total of 3435 medical students from the United States who applied to an ophthalmology residency program from 2003 to 2008 were included.
Methods:
Matched and unmatched applicants were compared and stratified by predictor variables, including United States Medical Licensing Examination (USMLE) Step 1 score, Alpha Omega Alpha (AOA) status, medical school reputation, and medical school geographic region. Differences in proportions were analyzed using (Read more...)
Enhanced Detection of Open-angle Glaucoma with an Anatomically Accurate Optical Coherence Tomography–Derived Neuroretinal Rim Parameter
Objective:
Neuroretinal rim assessment based on the clinical optic disc margin (DM) lacks a sound anatomic basis for 2 reasons: (1) The DM is not reliable as the outer border of rim tissue because of clinically and photographically invisible extensio…
Antioxidant oral supplement might help in macular degeneration
NEW YORK (Reuters Health) – An antioxidant oral supplement (Ocuvite, Bausch and Lomb), in particular
its lutein component, may provide benefits in patients with early age-related macular degeneration (AMD), according
to new findings from a seco…
More Evidence Retinal Thinning May Track MS Progression
MS patients with new T2 lesions and disease duration of less than 5 years have the fastest thinning of ganglion cell and inner plexiform layers, a new study has found. Medscape Medical News
Clinical Notes: Circadian Drug Hits Trial Goal
(MedPage Today) — Individuals whose circadian rhythms are disrupted because of total blindness achieved relief from a new drug, results of a clinical trial indicated. Also this week: Stimuvax fails to help lung cancer patients.