Topical Cyclosporine in the Treatment of Allergic Conjunctivitis: A Meta-analysis – Corrected Proof
Purpose: To assess the efficacy and safety of topical cyclosporine versus placebo in the treatment of allergic conjunctivitis.Design: Systematic review and meta-analysis.Participants: Seven qualified studies incorporating 306 eyes of 153 patients were analyzed.Methods: Searches of randomized controlled trials were conducted in MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, ClinicalTrials.gov, and the World Health Organization International Clinical Trials Registry Platform.Main Outcome Measures: We assessed the methodologic quality of individual included trials and performed meta-analyses using the random effects model if P<0.1 in the test for heterogeneity, or otherwise used the fixed effect model. We assessed scores of composite signs (Read more...)