Reply
We thank Abramson and associates for their comments regarding our report and welcome the opportunity to clarify our conclusions. In our study, only 1 of 252 patients that had received systemic chemotherapy developed pineoblastoma, while 3 of 156 patients, who did not receive chemotherapy, developed pineoblastoma. Abramson and associates correctly point out that only patients with the genetic form of retinoblastoma are at risk for pineoblastoma and hence only they should be included in the analysis, a fact that we well recognize. However, we wish to point out that their interpretation of our study data is not accurate. In our study, (Read more...)