New pretreatment protocol may prevent foaming during drug impregnation of IOLs

Ljubljana, SLOVENIA — An innovative pretreatment process prevents the foaming phenomenon that affects the optical quality of IOLs during impregnation with drugs, according to one speaker. Using IOLs for sustained delivery of drugs over a period of 10 or more days could provide effective protection against postoperative infections, primarily endophthalmitis. Today’s technology allows not just superficial coating but impregnation of the lens polymer. However, if crucial steps of this complex process are not properly controlled, the CO₂ released during the depressurization stage may be trapped in the polymer, forming bubbles.