Corneal cross-linking ready for modified, scientifically based approaches

The concept of corneal collagen cross-linking (CXL), relies on the potential to induce morphological changes on the fibrils of the anterior stroma by a photochemical process. The interaction between UVA photons and the riboflavin molecules leads to the release of hyperactive free radicals, with the immediate effect of forming fiber-fiber and fiber-matrix bondings, David Touboul, MD, said in the Commentary column of the April 2014 issue of Ocular Surgery News Europe Edition. The sustained effect is a substantial cellular remodeling due to the cytotoxicity of these radicals, the intensity of (Read more...)