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Endothelial graft interface analysis shows disorganized collagen patterns induced by femtosecond laser
PARIS — Structural modifications induced in the posterior stromal collagen by the laser may explain the poorer visual results of femtosecond laser-assisted endothelial keratoplasty compared with mechanical methods, according to a study. During the SFO-EVER symposium at the meeting of the French Society of Ophthalmology, Jean-Louis Bourges, MD, PhD, presented the results of in vivo confocal microscopy performed on femtosecond laser-assisted endothelial keratoplasty grafts in 26 patients. Electron microscopy was used for further observation on histological specimens of explanted grafts in four patients who needed conversion.